Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Alexandra M, Adams"'
1
Akademický článek
Tumor lysate particle only vaccine (TLPO) vs. Tumor lysate particle-loaded, dendritic cell vaccine (TLPLDC) to prevent recurrence in resected stage III/IV melanoma patients: Results of a phase I/IIa trial
Autor: Spencer G. Van Decar, Elizabeth L. Carpenter, Alexandra M. Adams, Robert C. Chick, Guy T. Clifton, Alex Stojadinovic, Timothy J. Vreeland, Franklin A. Valdera, Ankur Tiwari, Anne E. O'Shea, Patrick M. McCarthy, Diane F. Hale, Phillip M Kemp Bohan, Annelies T. Hickerson, Jessica L. Cindass, John Hyngstrom, Adam C. Berger, James W. Jakub, Jeffrey J. Sussman, Montaser Shaheen, Xianzhong Yu, Thomas Wagner, Mark B. Faries, George E. Peoples
Publikováno v: Cancer Treatment and Research Communications, Vol 41, Iss , Pp 100843- (2024)
Background: The autologous tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine is produced from dendritic cells (DC) loaded ex vivo with autologous tumor lysate (TL). TLPLDC has been shown to decrease recurrence in resected Stage III/IV me
Externí odkaz: https://doaj.org/article/26a0b32110ad4f309bb06e391026d393
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2
Akademický článek
Prospective, randomized, double-blind phase 2B trial of the TLPO and TLPLDC vaccines to prevent recurrence of resected stage III/IV melanoma: a prespecified 36-month analysis
Autor: Timothy Vreeland, Diane Hale, Mark Faries, George E Peoples, Xianzhong Yu, Patrick McCarthy, Jessica Cindass, John Hyngstrom, James Jakub, Montaser F Shaheen, Guy Travis Clifton, Elizabeth Lee Carpenter, Spencer Van Decar, Alexandra M Adams, Anne E O’Shea, Robert Connor Chick, Franklin A Valdera, Ankur Tiwari, Phillip Kemp Bohan, Annelies Hickerson, Todd Smolinsky, Katryna Thomas, Adam C Berger, Jeffrey J Sussman, Thomas E Wagner
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background The tumor lysate, particle-loaded, dendritic cell (TLPLDC) vaccine is made by ex vivo priming matured autologous dendritic cells (DCs) with yeast cell wall particles (YCWPs) loaded with autologous tumor lysate (TL). The tumor lysate, parti
Externí odkaz: https://doaj.org/article/77f16b8a4e484136af598ca7e78be392
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3
Akademický článek
Improved immunoassay sensitivity and specificity using single-molecule colocalization
Autor: Amani A. Hariri, Sharon S. Newman, Steven Tan, Dan Mamerow, Alexandra M. Adams, Nicolò Maganzini, Brian L. Zhong, Michael Eisenstein, Alexander R. Dunn, H. Tom Soh
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
A major challenge of enzyme-linked immunosorbent assays is discriminating true signal from non-specific binding. Here the authors present a Single-Molecule Colocalization Assay (SiMCA) which eliminates such effects, enabling reproducible detection of
Externí odkaz: https://doaj.org/article/18c976fb74b244c38652006166953114
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4
Akademický článek
Tumor infiltrating lymphocytes as an endpoint in cancer vaccine trials
Autor: Patrick M. McCarthy, Franklin A. Valdera, Todd R. Smolinsky, Alexandra M. Adams, Anne E. O’Shea, Katryna K. Thomas, Spencer Van Decar, Elizabeth L. Carpenter, Ankur Tiwari, John W. Myers, Diane F. Hale, Timothy J. Vreeland, George E. Peoples, Alex Stojadinovic, Guy T. Clifton
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
Checkpoint inhibitors have invigorated cancer immunotherapy research, including cancer vaccination. Classic early phase trial design and endpoints used in developing chemotherapy are not suited for evaluating all forms of cancer treatment. Peripheral
Externí odkaz: https://doaj.org/article/bc7c7eccb0dc43ea82221b1220d847ed
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5
Akademický článek
Development of an E. coli-based norbaeocystin production platform and evaluation of behavioral effects in rats
Autor: Alexandra M. Adams, Nicholas A. Anas, Abhishek K. Sen, Jordan D. Hinegardner-Hendricks, Philip J. O’Dell, William J. Gibbons, Jr., Jessica E. Flower, Matthew S. McMurray, J. Andrew Jones
Publikováno v: Metabolic Engineering Communications, Vol 14, Iss , Pp e00196- (2022)
Interest in the potential therapeutic efficacy of psilocybin and other psychedelic compounds has escalated significantly in recent years. To date, little is known regarding the biological activity of the psilocybin pathway intermediate, norbaeocystin
Externí odkaz: https://doaj.org/article/8618c3a378634ed5a5a5fbbbc8f123f5
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7
Morbidity and Mortality of Non-pancreatectomy operations for pancreatic cancer: An ACS-NSQIP analysis
Autor: Alexandra M. Adams, Bradley N. Reames, Robert W. Krell
Publikováno v: The American Journal of Surgery. 225:315-321
Patients with pancreas cancer may undergo palliative gastrointestinal or biliary bypass. Recent comparisons of post-operative outcomes following such procedures are lacking.We analyzed patients undergoing exploration, gastrojejunostomy, biliary bypas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5cca340a7a53f0621ba1ee58227595
https://doi.org/10.1016/j.amjsurg.2022.08.012
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