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of 6
pro vyhledávání: '"Alexandra Livingstone"'
Autor:
Andrew Coxon, Rupen Desai, Tanner M Johanns, Gavin P Dunn, Saad M Khan, Alexandra Livingstone, Allegra Petti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Glioblastoma is a fatal disease despite aggressive multimodal therapy. PD-1 blockade, a therapy that reinvigorates hypofunctional exhausted CD8 T cells (Tex) in many malignancies, has not shown efficacy in glioblastoma. Loss of CD4 T cells
Externí odkaz:
https://doaj.org/article/e57e0b22c39e49c4bbbdfaaa8929a27b
Publikováno v:
Neuro-Oncology. 24:vii137-vii138
Glioblastoma is a primary brain tumor with a dismal prognosis. CD4 T cell responses to neoantigen vaccines or checkpoint blockade immunotherapy impact the tumor microenvironment. However, the function of CD4 T cells in glioblastoma remains understudi
Autor:
Saad M Khan, Rupen Desai, Andrew Coxon, Alexandra Livingstone, Gavin P Dunn, Allegra Petti, Tanner M Johanns
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e005293
BackgroundGlioblastoma is a fatal disease despite aggressive multimodal therapy. PD-1 blockade, a therapy that reinvigorates hypofunctional exhausted CD8 T cells (Tex) in many malignancies, has not shown efficacy in glioblastoma. Loss of CD4 T cells
Autor:
Jay Bowman-Kirigin, Dale Kobayashi, Alexandra Livingstone, Brian Saunders, Max Schaettler, Connor Liu, Vivek Durai, Eric Leuthardt, Albert Kim, Gregory Zipfel, Joshua Osbun, Michael Chicoine, Kenneth Murphy, Bernd Zinselmeyer, Tanner Johanns, Gavin Dunn
Publikováno v:
Neuro Oncol
The antigen presenting cell that primes T cells in the central nervous system (CNS) remains unknown. Outside the CNS, the conventional dendritic cell 1 (cDC1) subset presents antigen to and primes CD8 T cells. However, the steady-state CNS parenchyma
Publikováno v:
Current Protocols in Immunology. 72
Cytotoxic T lymphocytes (CTL) kill target cells on the basis of cell-surface antigen recognition and are important in the host response to tumors, transplants, and viruses. This unit presents several protocols for generating and measuring CTL activit
Autor:
Alexandra Livingstone
Publikováno v:
Immunology Methods Manual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2753cb93925f0cf1fadced6168274b9e
https://doi.org/10.1016/b978-012442710-5.50158-1
https://doi.org/10.1016/b978-012442710-5.50158-1