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pro vyhledávání: '"Alexandra Lisovsky"'
Publikováno v:
Biomaterials. 98:203-214
Poly(methacrylic acid-co-methyl methacrylate) (MAA) beads promote a vascular regenerative response when used in diabetic wound healing. Previous studies reported that MAA beads modulated the expression of sonic hedgehog (Shh) and inflammation related
Autor:
Michael V. Sefton, Alexandra Lisovsky, Andrew Emili, Hongbo Guo, Ilana Talior-Volodarsky, Michael Dean Chamberlain, Redouan Mahou, Laura A. Wells, Ruth Isserlin
Publikováno v:
Proceedings of the National Academy of Sciences. 112:10673-10678
An unbiased phosphoproteomic method was used to identify biomaterial-associated changes in the phosphorylation patterns of macrophage-like cells. The phosphorylation differences between differentiated THP1 (dTHP1) cells treated for 10, 20, or 30 min
Autor:
Michael V. Sefton, Alexandra Lisovsky
Publikováno v:
Biomaterials. 102
Previously, poly(methacrylic acid-co-methyl methacrylate) (MAA) beads were shown to improve vessel formation with a concomitant increase in the expression of the sonic hedgehog (Shh) gene, a pleiotropic factor implicated in vascularization. The aim o
Publikováno v:
Advanced healthcare materials. 4(16)
In diabetic patients the development of chronic non-healing wounds is a common complication. A methacrylic acid-based biomaterial is a vascular regenerative material that enhances diabetic healing without the use of cells or growth factors. The bioac
Publikováno v:
Biomaterials. 33(21)
The expression of native sonic hedgehog (Shh) was significantly increased in poly(methacrylic acid-co-methyl methacrylate) bead (MAA) treated wounds at day 4 compared to both poly(methyl methacrylate) bead (PMMA) treated and untreated wounds in diabe