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pro vyhledávání: '"Alexandra Lemaçon"'
Autor:
Salvatore La Rosa, Fabien Leurquin, Colin L. Gibson, Alexandra Lemaçon, Colin J. Suckling, Peter H. Boyle, Kyuji Ohta
Publikováno v:
Tetrahedron. 60:943-959
Variously substituted 7-deazaguanines are of interest as inhibitors of GTP cyclohydrolase I, the first enzyme in the biosynthetic pathway leading to dihydrofolate and tetrahydrobiopterin. Methods are described for the synthesis of 7-deazaguanines sub