Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexandra L. Thomas"'
Autor:
Jessica Bauer, Md Abul Bashar Emon, Jonas J. Staudacher, Alexandra L. Thomas, Jasmin Zessner-Spitzenberg, Georgina Mancinelli, Nancy Krett, M. Taher Saif, Barbara Jung
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/cfbd7d1d1968415aae90d7b388524b05
Autor:
Tohru Fukai, Georgina Mancinelli, Alexandra L. Thomas, Arundhati Jana, Barbara Jung, Nancy Krett, Masuko Ushio-Fukai, Jessica Bauer, Grace Guzman, Archita Das
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227916 (2020)
PLoS ONE, Vol 15, Iss 1, p e0227916 (2020)
BackgroundColorectal cancer remains a deadly cancer due to metastatic disease. To understand the molecular mechanisms of metastasis in colon cancer, we investigated whether the copper chaperone antioxidant-1 (Atox1) protein plays a role in this proce
Autor:
Jasmin Zessner-Spitzenberg, Abdul Bashar Emon, Jonas J. Staudacher, M. Taher A. Saif, Barbara Jung, Georgina Mancinelli, Jessica Bauer, Nancy Krett, Alexandra L. Thomas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Colorectal cancer (CRC) is the second deadliest cancer in the US due to its propensity to metastasize. Stromal cells and especially cancer-associated fibroblasts (CAF) play a critical biophysical role in cancer progression, but the precise pro-metast
Autor:
Eric C. Hobson, Jacqueline S. Jeruss, Seungjin Shin, Kelly B. Arnold, Alexandra L. Thomas, Yining Zhang, Lonnie D. Shea, Joseph T. Decker
Publikováno v:
Biotechnology and Bioengineering. 114:2085-2095
The development of resistance to targeted therapeutics is a challenging issue for the treatment of cancer. Cancers that have mutations in BRCA, a DNA repair protein, have been treated with poly(ADP-ribose) polymerase (PARP) inhibitors, which target a
Autor:
Jessica Bauer, Barbara Jung, David C. Whitcomb, Giamila Fantuzzi, Karla J. Castellanos, Yinglin Xia, Georgina Mancinelli, Georgios I. Papachristou, Cemal Yazici, Rosa F. Hwang, Nancy Krett, Alexandra L. Thomas
Publikováno v:
Clinical and Translational Gastroenterology
INTRODUCTION: Acute pancreatitis (AP) is a healthcare challenge with considerable mortality. Treatment is limited to supportive care, highlighting the need to investigate disease drivers and prognostic markers. Activin A is an established mediator of
Autor:
Jasmin Zessner-Spitzenberg, Abul Bashar Emon, Alexandra L. Thomas, Jessica Bauer, M. Taher A. Saif, Barbara Jung, Jonas J. Staudacher, Georgina Mancinelli, Nancy Krett
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports
Scientific Reports
Colorectal cancer (CRC) is the second deadliest cancer in the US due to its propensity to metastasize. Stromal cells and especially cancer-associated fibroblasts (CAF) play a critical biophysical role in cancer progression, but the precise pro-metast
Publikováno v:
Gene Rep
Although overall survival in colorectal cancer (CRC) is increasing steadily due to progress in screening, therapeutic options and precise diagnostic tools remain scarce. As the understanding of CRC as a complex and multifactorial condition moves forw
Autor:
Alexandra L. Thomas
Publikováno v:
Merrill Series on The Research Mission of Public Universities. :7-10
Autor:
Hanne Lind, Randala Hamden, Kailey Oppat, Amina Guo, Danijela Dokic, Jacqueline S. Jeruss, Alexandra L. Thomas, Aaron Thomas, Angela Hong, Elana Rosenthal
Publikováno v:
Cell cycle (Georgetown, Tex.). 16(15)
Triple negative breast cancer (TNBC) is a highly aggressive breast cancer subtype that lacks effective targeted therapies. Although TNBC is not defined by specific therapeutic targets, a subset of patients have tumors that overexpress cyclins. High c
Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer
Autor:
Lei Wan, Alexandra L. Thomas, Jia Wu, Lonnie D. Shea, Jacqueline S. Jeruss, Danijela Dokic, Joseph T. Decker, Kristine E. Konopka, Jenna R. Stoehr, Shreyas S. Rao, Virginia G. Kaklamani
Publikováno v:
Oncotarget
// Shreyas S. Rao 1 , Jenna Stoehr 2 , Danijela Dokic 3 , Lei Wan 4 , Joseph T. Decker 5 , Kristine Konopka 6 , Alexandra L. Thomas 7 , Jia Wu 8 , Virginia G. Kaklamani 9 , Lonnie D. Shea 3, 5 and Jacqueline S. Jeruss 3, 4, 5, 6 1 Department of Chemi