CHICKN: extraction of peptide chromatographic elution profiles from large scale mass spectrometry data by means of Wasserstein compressive hierarchical cluster analysis

Autor: Olga Permiakova, Romain Guibert, Alexandra Kraut, Thomas Fortin, Anne-Marie Hesse, Thomas Burger

Publikováno v: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-30 (2021)

Abstract Background The clustering of data produced by liquid chromatography coupled to mass spectrometry analyses (LC-MS data) has recently gained interest to extract meaningful chemical or biological patterns. However, recent instrumental pipelines

Externí odkaz: https://doaj.org/article/09ef442cca6e4bf58b38e9b9338b97f7

Mass Spectrometry-Based Characterization of the Virion Proteome, Phosphoproteome, and Associated Kinase Activity of Human Cytomegalovirus

Autor: Yohann Couté, Alexandra Kraut, Christine Zimmermann, Nicole Büscher, Anne-Marie Hesse, Christophe Bruley, Marco De Andrea, Christina Wangen, Friedrich Hahn, Manfred Marschall, Bodo Plachter

Publikováno v: Microorganisms, Vol 8, Iss 6, p 820 (2020)

The assembly of human cytomegalovirus (HCMV) virions is an orchestrated process that requires, as an essential prerequisite, the complex crosstalk between viral structural proteins. Currently, however, the mechanisms governing the successive steps in

Externí odkaz: https://doaj.org/article/033374bdb6c744bdbbd9566fd3bbcb9b

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins

Autor: Mirjam Steingruber, Alexandra Kraut, Eileen Socher, Heinrich Sticht, Anna Reichel, Thomas Stamminger, Bushra Amin, Yohann Couté, Corina Hutterer, Manfred Marschall

Publikováno v: Viruses, Vol 8, Iss 8, p 219 (2016)

The human cytomegalovirus (HCMV)-encoded cyclin-dependent kinase (CDK) ortholog pUL97 associates with human cyclin B1 and other types of cyclins. Here, the question was addressed whether cyclin interaction of pUL97 and additional viral proteins is de

Externí odkaz: https://doaj.org/article/9a5bea6019d64ba38adfec8370f47895

Immune-Mediated Rippling Muscle Disease Associated With Thymoma and Anti-MURC/Cavin-4 Autoantibodies

Autor: Juliette Svahn, Laurent Coudert, Nathalie Streichenberger, Alexandra Kraut, Alice Gravier-Dumonceau-Mazelier, Ludivine Rotard, Laurence Calemard-Michel, Rita Menassa, Elisabeth Errazuriz-Cerda, Lara Chalabreysse, Alexis Osseni, Christophe Vial, Laurentiu Jomir, François Tronc, Do Le Duy, Emilien Bernard, Vincent Gache, Yohann Couté, Vincent Jacquemond, Laurent Schaeffer, Pascal Leblanc

Publikováno v: Neurology - Neuroimmunology Neuroinflammation. 10:e200068

ObjectivesRippling muscle disease (RMD) is characterized by muscle stiffness, muscle hypertrophy, and rippling muscle induced by stretching or percussion. Hereditary RMD is due to sequence variants in theCAV3andPTRF/CAVIN1genes encoding Caveolin-3 or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6418adda017655df21395c05c0111615
https://doi.org/10.1212/nxi.0000000000200068

Identification of the Arabidopsis Calmodulin-Dependent NAD+ Kinase That Sustains the Elicitor-Induced Oxidative Burst

Autor: Michel Matringe, Giovanni Finazzi, Guillaume Decros, Yohann Couté, Alexandra Kraut, Christian Mazars, Alex Costa, Gilles Curien, Cécile Giustini, Yves Gibon, Elisa Dell’Aglio

Publikováno v: Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2019, 181 (4), pp.1449-1458. ⟨10.1104/pp.19.00912⟩
Plant Physiology, 2019, 181 (4), pp.1449-1458. ⟨10.1104/pp.19.00912⟩

NADP(H) is an essential cofactor of multiple metabolic processes in all living organisms, and in plants, NADP(H) is required as the substrate of Ca2+-dependent NADPH oxidases, which catalyze a reactive oxygen species burst in response to various stim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc78a3bfcb644d3a8880da425faa1b11
https://doi.org/10.1104/pp.19.00912