Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexandra Koumoutsi"'
Autor:
Carlos Geert Pieter Voogdt, Surya Tripathi, Stefan Oliver Bassler, Saria A. McKeithen-Mead, Emma R. Guiberson, Alexandra Koumoutsi, Afonso Martins Bravo, Cullen Buie, Michael Zimmermann, Justin L. Sonnenburg, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113519- (2024)
Summary: The critical role of the intestinal microbiota in human health and disease is well recognized. Nevertheless, there are still large gaps in our understanding of the functions and mechanisms encoded in the genomes of most members of the gut mi
Externí odkaz:
https://doaj.org/article/f55492c84db847c78fb9dfafefb55708
Autor:
Surya Tripathi, Carlos Geert Pieter Voogdt, Stefan Oliver Bassler, Mary Anderson, Po-Hsun Huang, Nazgul Sakenova, Tümay Capraz, Sunit Jain, Alexandra Koumoutsi, Afonso Martins Bravo, Valentine Trotter, Michael Zimmerman, Justin L. Sonnenburg, Cullen Buie, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113517- (2024)
Summary: Randomly barcoded transposon mutant libraries are powerful tools for studying gene function and organization, assessing gene essentiality and pathways, discovering potential therapeutic targets, and understanding the physiology of gut bacter
Externí odkaz:
https://doaj.org/article/023823f8c8824e889806312e660b82aa
Autor:
Marco Galardini, Alexandra Koumoutsi, Lucia Herrera-Dominguez, Juan Antonio Cordero Varela, Anja Telzerow, Omar Wagih, Morgane Wartel, Olivier Clermont, Erick Denamur, Athanasios Typas, Pedro Beltrao
Publikováno v:
eLife, Vol 6 (2017)
Understanding how genetic variation contributes to phenotypic differences is a fundamental question in biology. Combining high-throughput gene function assays with mechanistic models of the impact of genetic variants is a promising alternative to gen
Externí odkaz:
https://doaj.org/article/e4938a19e76246759c429b2d981060eb
Autor:
Andrew N Gray, Alexander JF Egan, Inge L van't Veer, Jolanda Verheul, Alexandre Colavin, Alexandra Koumoutsi, Jacob Biboy, A F Maarten Altelaar, Mirjam J Damen, Kerwyn Casey Huang, Jean-Pierre Simorre, Eefjan Breukink, Tanneke den Blaauwen, Athanasios Typas, Carol A Gross, Waldemar Vollmer
Publikováno v:
eLife, Vol 4 (2015)
To maintain cellular structure and integrity during division, Gram-negative bacteria must carefully coordinate constriction of a tripartite cell envelope of inner membrane, peptidoglycan (PG), and outer membrane (OM). It has remained enigmatic how th
Externí odkaz:
https://doaj.org/article/04fecc86150049b7bfec873c33e51564
Autor:
Yi-Cheng Sun, Alexandra Koumoutsi, Clayton Jarrett, Kevin Lawrence, Frank C Gherardini, Creg Darby, B Joseph Hinnebusch
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19267 (2011)
Yersinia pestis forms a biofilm in the foregut of its flea vector that promotes transmission by flea bite. As in many bacteria, biofilm formation in Y. pestis is controlled by intracellular levels of the bacterial second messenger c-di-GMP. Two Y. pe
Externí odkaz:
https://doaj.org/article/c1ebd5439b11413e901d1ce9a6f7fee4
Autor:
Athanasios Typas, Morgane Wartel, Omar Wagih, Erick Denamur, Anja Telzerow, Juan Antonio Cordero Varela, Alexandra Koumoutsi, Olivier Clermont, Marco Galardini, Lucia Herrera-Dominguez, Pedro Beltrao
SummaryUnderstanding how genetic variation contributes to phenotypic differences is a fundamental question in biology. Here, we set to predict fitness defects of an individual using mechanistic models of the impact of genetic variants combined with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5a6c15164370370ee6ce2b6bf4a351
https://doi.org/10.1101/141879
https://doi.org/10.1101/141879
Autor:
Athanasios Typas, Erick Denamur, Pedro Beltrao, Morgane Wartel, Olivier Clermont, Lucia Herrera-Dominguez, Omar Wagih, Marco Galardini, Alexandra Koumoutsi, Juan Antonio Cordero Varela, Anja Telzerow
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, 6
eLife, Vol 6 (2017)
eLife, 6
Understanding how genetic variation contributes to phenotypic differences is a fundamental question in biology. Combining high-throughput gene function assays with mechanistic models of the impact of genetic variants is a promising alternative to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ada068fc594d6774ae46953fda9d9d
Publikováno v:
Microbial Physiology. 16:14-24
The genome of environmental Bacillus amyloliquefaciens FZB42 harbors numerous gene clusters involved in synthesis of antifungal and antibacterial acting secondary metabolites. Five gene clusters, srf, bmy, fen, nrs, dhb, covering altogether 137 kb, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e3e2d9362d97c24d644882e531a4055
https://doi.org/10.1159/000142891
https://doi.org/10.1159/000142891
Autor:
Alexandra Koumoutsi, Isabelle Heinemeyer, Gerhard Gottschalk, Wolfgang R. Hess, Xiao-Hua Chen, Roderich D. Süssmuth, Rainer Borriss, Björn Voss, Birgit Voigt, Kathrin Schneider, Andreas Eisenreich, Heiko Liesegang, Oleg N. Reva, Joachim Vater, Peter R. Jungblut, Burkhard Morgenstern, Romy Scholz, Helmut Junge, Axel Strittmatter
Publikováno v:
Molecular Microbial Ecology of the Rhizosphere
Bacillus amyloliquefaciens FZB42 is a Gram-positive, plant-associated bacterium, which stimulates plant growth and produces secondary metabolites that suppress soil-borne plant pathogens. Its 3,918-kb genome, containing an estimated 3,693 protein-cod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6658ff098ff7c809d76b90fc2bd467e
https://doi.org/10.1038/nbt1325
https://doi.org/10.1038/nbt1325
Autor:
Alexandre Colavin, Tanneke den Blaauwen, Eefjan Breukink, Jolanda Verheul, Kerwyn Casey Huang, Jacob Biboy, A. F. Maarten Altelaar, Alexander J. F. Egan, Mirjam J Damen, Alexandra Koumoutsi, Jean-Pierre Simorre, Andrew N. Gray, Inge L. van't Veer, Waldemar Vollmer, Athanasios Typas, Carol A. Gross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb0a44856f70bd34d07464f7b68cf87d
https://doi.org/10.7554/elife.07118.026
https://doi.org/10.7554/elife.07118.026