From niche to mainstream: The dilemmas of scaling up sustainable alternatives

Autor: Alexandra Palzkill, Verena Hermelingmeier, Markus Egermann, Paul Suski, Karoline Augenstein, David P. M. Lam, Melanie Jaeger-Erben, Boris Bachmann, Annaliesa Hilger, Alexandra Kessler, Timo von Wirth

Publikováno v: GAIA-Ecological Perspectives for Science and Society, 29(3), 143-147. Oekom Verlag
Augenstein, K, Bachmann, B, Egermann, M, Hermelingmeier, V, Hilger, A, Jäger-Erben, M, Kessler, A, Lam, D, Palzkill, A, Suski, P & von Wirth, T 2020, ' From niche to mainstream : the dilemmas of scaling up sustainable alternatives ', GAIA-Ecological Perspectives for Science and Societa, vol. 29, no. 3, pp. 143-147 . https://doi.org/10.14512/gaia.29.3.3

At the heart of transition research lies the question of how to “scale up” sustainable alternatives from a protected niche to the creation of mainstream practices.While upscaling processes are often seen as an essential element that contributes t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcca128342a8034939957e2b9bdcb395
https://pure.eur.nl/en/publications/574512c5-cd89-4af5-b2ef-c0e0a201f34b

Multiple variants of the archaeal DNA rudivirus SIRV1 in a single host and a novel mechanism of genomic variation

Autor: David Prangishvili, Xu Peng, Roger A. Garrett, Hien Phan, Alexandra Kessler

Publikováno v: Molecular Microbiology. 54:366-375

The DNA rudivirus SIRV1 of the hyperthermophilic archaeon Sulfolobus shows exceptional properties. Viral isolates invariably contain a population of variants with different but closely related genomes. Upon propagation in a given host strain, one or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e503be649f6c2314e1f72c8237abd52a
https://doi.org/10.1111/j.1365-2958.2004.04287.x

Phosphoinositolglycan-Peptides from Yeast Potently Induce Metabolic Insulin Actions in Isolated Rat Adipocytes, Cardiomyocytes, and Diaphragms

Autor: Alexandra Kessler, Günter Müller, Jürgen Eckel, Anna Crecelius, Susanne Wied

Publikováno v: Endocrinology. 138:3459-3475

Polar headgroups of free glycosyl-phosphatidylinositol (GPI) lipids or protein-bound GPI membrane anchors have been shown to exhibit insulin-mimetic activity in different cell types. However, elucidation of the molecular mode of action of these phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb5d86f1445889b3b34c7d6f7320f3e
https://doi.org/10.1210/endo.138.8.5308

A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters

Autor: J. Iñaki Guijarro, Stephen D. Bell, Alexandra Kessler, Muriel Delepierre, Thierry Rose, Nicole Desnoues, Guennadi Sezonov, David Prangishvili

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2006, 34 (17), pp.4837-45. ⟨10.1093/nar/gkl502⟩
Nucleic Acids Research, Oxford University Press, 2006, 34 (17), pp.4837-45. ⟨10.1093/nar/gkl502⟩

International audience; While studying gene expression of the rudivirus SIRV1 in cells of its host, the hyperthermophilic crenarchaeon Sulfolobus, a novel archaeal transcriptional regulator was isolated. The 14 kDa protein, termed Sulfolobus transcri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943fb0b9316da161a39cbe9dc6bdb645
https://hal-pasteur.archives-ouvertes.fr/pasteur-00364745

Rab11 is associated with GLUT4-containing vesicles and redistributes in response to insulin

Autor: H. E. Meyer, Alexandra Kessler, D. Immler, E. Tomas, Jürgen Eckel, Antonio Zorzano

Publikováno v: Diabetologia. 43(12)

Aims/hypothesis To identify a GTPase of 24,000 M(r) which we recently found to co-localize with GLUT4 in cardiac muscle. Methods A 24,000 M(r)-GTP-binding fraction was purified from pig heart by a three-step chromatographic procedure, followed by two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ffd4d4a3ec3b2653894f43729f70e9
https://pubmed.ncbi.nlm.nih.gov/11151761