Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexandra Kemmer-Brück"'
Autor:
John L. Perez, Isabel Vogler, Evelyna Derhovanessian, Gábor Boros, David A. Cooper, Camila R. Fontes-Garfias, Kristen E. Pascal, Armin Schultz, Alexander Muik, Martin Bexon, Pei Yong Shi, Peter Koch, Ann Kathrin Eller, Verena Lörks, Mark Cutler, Daniel Maurus, Ludwig Heesen, Philip R. Dormitzer, Ugur Sahin, Kathrin U. Jansen, Manuel Tonigold, Jan Grützner, Azita J. Mahiny, Corinna Rosenbaum, Stefanie Bolte, Mathias Vormehr, Marie Cristine Kühnle, Sybille Baumann, Asaf Poran, Alexander Ulges, Alexandra Kemmer-Brück, Christos A. Kyratsous, Dirk Becker, Özlem Türeci, Alina Baum, Sebastian Brachtendorf, Lena M. Kranz, Carsten Boesler, Rolf Hilker, Tania Palanche, Julian Sikorski, Nicole Bidmon, Ulrich Luxemburger, David J. Langer, Jesse Z. Dong, Gábor Szabó, Jasmin Quandt, Katalin Karikó, Jonas Reinholz
Publikováno v:
Nature. 595:572-577
BNT162b2, a lipid nanoparticle (LNP) formulated nucleoside-modified messenger RNA (mRNA) that encodes the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S) stabilized in the prefusion conformation, has demonstrated 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0154147b441b18af735efb00657c62f
https://doi.org/10.1038/s41586-021-03653-6
https://doi.org/10.1038/s41586-021-03653-6
Autor:
Rolf Hilker, Jasmin Quandt, Boris Fischer, Jan Grützner, Kena A. Swanson, Sebastian Brachtendorf, Julian Sikorski, Mark Cutler, Kristen E. Pascal, Alexandra Kemmer-Brück, Lena M. Kranz, Dirk Becker, Katalin Karikó, Philip R. Dormitzer, Corinna Rosenbaum, Ulrich Luxemburger, Tania Palanche, Ugur Sahin, Camila R. Fontes-Garfias, Özlem Türeci, David A. Cooper, Armin Schultz, Alexander Muik, Ingrid L. Scully, Marie Cristine Kühnle, Jakob Loschko, Pei Yong Shi, Warren Kalina, Daniel Maurus, Verena Lörks, David J. Langer, Stefanie Bolte, Isabel Vogler, Mathias Vormehr, Christos A. Kyratsous, Carsten Boesler, Ann Kathrin Eller, Martin Bexon, Alina Baum, John L. Perez, Kathrin U. Jansen, Evelyna Derhovanessian
Publikováno v:
Nature
An effective vaccine is needed to halt the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic. Recently, we reported safety, tolerability and antibody response data from an ongoing placebo-controlled, observer-blinded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e759c17cfd365c57e05fc7d355e9a4f
https://doi.org/10.1038/s41586-020-2814-7
https://doi.org/10.1038/s41586-020-2814-7
Autor:
Christoph Huber, Andreas Pinter, Heinrich Haas, Tana Omokoko, Verena Müller, Julian Sikorski, Alexandra Kemmer-Brück, Malte Stein, Inga Liebig, Claudia Tolliver, Melanie Leierer, Jessica C. Hassel, Petra Oehm, Sebastian Attig, Isabel Vogler, Evelyna Derhovanessian, Juliane Quinkhardt, Janina Caspar, Lisa Hebich, Jochen Utikal, Özlem Türeci, Carmen Loquai, Maike Gold, Roland Kaufmann, Sebastian Kreiter, Ugur Sahin, Richard Rae, Andreas Kuhn, Stephan Grabbe, Doreen Schwarck-Kokarakis, Lena M. Kranz, Matthias Miederer, Daniel Maurus, Mathias Vormehr, Mustafa Diken, Katarina Cuk, Stephanie Renken, Heidrun Mitzel-Rink, Andrea Breitkreuz, Robert A. Jabulowsky, Alexander Hohberger
Publikováno v:
Nature. 585:107-112
Treating patients who have cancer with vaccines that stimulate a targeted immune response is conceptually appealing, but cancer vaccine trials have not been successful in late-stage patients with treatment-refractory tumours1,2. We are testing melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303f452f94121b674c882c38aa381209
https://doi.org/10.1038/s41586-020-2537-9
https://doi.org/10.1038/s41586-020-2537-9
Autor:
Warren Kalina, Evelyna Derhovanessian, David J. Langer, Alexander Muik, Jakob Loschko, Kristen E. Pascal, Daniel Maurus, Corinna Rosenbaum, Katalin Karikó, Mark Cutler, Stefanie Bolte, Armin Schultz, Christos A. Kyratsous, Isabel Vogler, Ingrid L. Scully, Ann Kathrin Eller, Dirk Becker, David A. Cooper, Jan Grützner, Pei Yong Shi, Julian Sikorski, Tania Palanche, Martin Bexon, Alexandra Kemmer-Brück, Rolf Hilker, Ulrich Luxemburger, Kathrin U. Jansen, Mathias Vormehr, Philip R. Dormitzer, Verena Lörks, Sebastian Brachtendorf, Lena M. Kranz, John L. Perez, Marie Cristine Kühnle, Jasmin Quandt, Boris Fischer, Kena A. Swanson, Özlem Türeci, Ugur Sahin, Camila R. Fontes-Garfias, Carsten Boesler, Alina Baum
Publikováno v:
Nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a440c230522e2d8f68ee1727420d6386
Autor:
Jochen Utikal, Isabel Vogler, Özlem Türeci, Tana Omokoko, Christoph Höller, Matthias Miller, Björn-Philipp Kloke, Inga Ortseifer, Sebastian Attig, Goran Martic, Barbara Schrörs, Andrea Breitkreuz, Christoph Huber, Janina Buck, Valesca Bukur, Alexander Hohberger, Andreas Kuhn, Anna Paruzynski, Martina Zillgen, Meike Witt, Sandra Heesch, Jan Diekmann, Stefanie Bolte, Evelyna Derhovanessian, Christoffer Gebhardt, Ulrich Luxemburger, Alexandra-Kemmer Brück, Petra Simon, Arbel D. Tadmor, Patrick Sorn, Stephan Grabbe, Felicitas Müller, Sebastian Kreiter, Martin Suchan, David Langer, Mathias Vormehr, Christian Albrecht, Mustafa Diken, Eva Godehardt, Claudia Tolliver, Romina Nemecek, Martin Löwer, Katharina H Schreeb, Barbara Kasemann, Richard Rae, Carmen Loquai, Olga Waksmann, Andrée Rothermel, Ugur Sahin, Janko Ciesla
Publikováno v:
Nature. 547:222-226
T cells directed against mutant neo-epitopes drive cancer immunity. However, spontaneous immune recognition of mutations is inefficient. We recently introduced the concept of individualized mutanome vaccines and implemented an RNA-based poly-neo-epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb4ccb9b5ff2d67566919b8a33f73443
https://doi.org/10.1038/nature23003
https://doi.org/10.1038/nature23003
Autor:
Marij J. P. Welters, Dominik Maurer, Ulrik Lassen, Martin Löwer, Bernhard Rossler, Ugur Sahin, Andreas von Deimling, Toni Weinschenk, Christian H. Ottensmeier, Elisa Rusch, Colette Song, Valérie Dutoit, Jordi Rodon, Norbert Hilf, Hans Skovgaard Poulsen, Nina Pawlowski, Francisco Martínez-Ricarte, Judith R. Kroep, Juan Sahuquillo, Claudia Wagner, Edward W. Green, Sonja Dorner, Cedrik M. Britten, Franziska Hoffgaard, Jens Fritsche, Ghazaleh Tabatabai, Stefan Stevanovic, Harpreet Singh-Jasuja, Marco Skardelly, Sabrina Kuttruff-Coqui, Hans-Georg Rammensee, Katharina Kiesel, Alexander Ulges, Carsten Reinhardt, Michael Platten, Alexandra Kemmer-Brück, Bracha Shraibman, Denis Migliorini, Sebastian Kreiter, Jordi Piro, Oliver Schoor, Valesca Bukur, Katrin Frenzel, Berta Ponsati, David Capper, Jorg Ludwig, Monika Stieglbauer, Regina Mendrzyk, Miriam Meyer, Sjoerd H. van der Burg, Evelyna Derhovanessian, Pierre-Yves Dietrich, Arie Admon, Arbel D. Tadmor, Manja Idorn, Wolfgang Wick, Hideho Okada, Per thor Straten, Sandra Heesch, Lukas Bunse, Christoph Huber, Katy J. McCann, Cécile Gouttefangeas, John C. Castle
Publikováno v:
Nature, 565(7738), 240
Nature, Vol. 565, No 7738 (2019) pp. 240-245
Nature, Vol. 565, No 7738 (2019) pp. 240-245
Patients with glioblastoma currently do not sufficiently benefit from recent breakthroughs in cancer treatment that use checkpoint inhibitors1,2. For treatments using checkpoint inhibitors to be successful, a high mutational load and responses to neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b11cf9d2f3e8456103640b3a57a625
https://hdl.handle.net/1887/119498
https://hdl.handle.net/1887/119498
Autor:
Evelyna Derhovanessian, Christine Anft, Özlem Türeci, Roland Kaufmann, Sebastian Attig, Andreas Kuhn, Martin Meng, Stephan Grabbe, Richard Rae, Christoph Huber, Malte Stein, Felicitas Müller, Andreas Pinter, Fatih Sari, Robert A. Jabulowsky, Mustafa Diken, Alexandra Deubel, Peter Langguth, Doreen Schwarck-Kokarakis, Daniel Maurus, Claudia Guertler, Ludwig Heesen, Katharina H Schreeb, Dirk Jäger, Heidrun Mitzel-Rink, Alexandra Kemmer-Brück, Christoffer Gebhardt, Sebastian Kreiter, Klaus Kuehlcke, Ulrich Luxemburger, Jochen Utikal, Ugur Sahin, Maike Gold, Jessica C. Hassel, Heinrich Haas, Carmen Loquai, Lena M. Kranz
Publikováno v:
Cancer Research. 78:CT156-CT156
Therapeutic vaccination with tumor antigen-encoding RNAs is being investigated in various clinical trials. Typically, the RNA vaccine is administered intradermally, subcutaneously or intranodally with the intention to get expression of the encoded an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0907642e81438a71b5b48780e7c43b09
https://doi.org/10.1158/1538-7445.am2018-ct156
https://doi.org/10.1158/1538-7445.am2018-ct156