Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexandra K. O'Donohue"'
Autor:
Alexandra K. O’Donohue, Xiaoying C. Li, Lucinda R. Lee, Emily R. Vasiljevski, David G. Little, Craig F. Munns, Aaron Schindeler
Publikováno v:
PLoS ONE, Vol 19, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/3d82683821c04af29c99c8f53b0d24f7
Autor:
Aiken Dao, Alexandra K. O'Donohue, Emily R. Vasiljevski, Justin D. Bobyn, David G. Little, Aaron Schindeler
Publikováno v:
Journal of Bone and Joint Infection. 8:81-89
Introduction: Osteomyelitis remains a major clinical challenge. Many published rodent fracture infection models are costly compared with murine models for rapid screening and proof-of-concept studies. We aimed to develop a dependable and cost-effecti
Autor:
Alexandra K. O'Donohue, Aiken Dao, Justin D. Bobyn, Craig F. Munns, David G. Little, Aaron Schindeler
Publikováno v:
Journal of Orthopaedic Research. 41:808-814
Osteogenesis imperfecta (OI) is a genetic bone fragility disorder that features frequent fractures. Bone healing outcomes are contingent on a proper balance between bone formation and resorption, and drugs such as bone morphogenetic proteins (BMPs) a
Publikováno v:
Journal of Bone and Mineral Research. 37:826-836
Osteogenesis imperfecta (OI) describes a series of genetic bone fragility disorders that can have a substantive impact on patient quality of life. The multidisciplinary approach to management of children and adults with OI primarily involves the admi
Autor:
Alexandra K. O'Donohue, Ya Xiao, Lucinda R. Lee, Timothy Schofield, Tegan L. Cheng, Craig F. Munns, Paul A. Baldock, Aaron Schindeler
Publikováno v:
Bone. 167:116636
The creation of murine gene knockout models to study bone gene functions often requires the resource intensive crossbreeding of Cre transgenic and gene-floxed strains. The developmental versus postnatal roles of genes can be difficult to discern in s
Autor:
Christopher J. Davey, Emily R. Vasiljevski, Alexandra K. O’Donohue, Simon C. Fleming, Aaron Schindeler
Publikováno v:
Journal of Biomedical Optics
Significance: Current methods for analyzing pathological muscle tissue are time consuming and rarely quantitative, and they involve invasive biopsies. Faster and less invasive diagnosis of muscle disease may be achievable using marker-free in vivo op
Autor:
Lucinda R. Lee, Aimee E. Holman, Xiaoying Li, Emily R. Vasiljevski, Alexandra K. O'Donohue, Tegan L. Cheng, David G. Little, Aaron Schindeler, Andrew Biggin, Craig F. Munns
Publikováno v:
Bone. 159:116378
Osteogenesis imperfecta (OI) or brittle bone disease is a genetic disorder that results in bone fragility. Bisphosphonates such as zoledronic acid (ZA) are used clinically to increase bone mass and reduce fracture risk. Human growth hormone (hGH) has
Autor:
Susan Smith, Christopher B Little, Aiken Dao, Sohel M Julovi, Katie Trinh, Alexandra K O’Donohue, Cindy Shu, Meena Shingde, Aaron Schindeler, Natasha M Rogers
Publikováno v:
RMD Open, Vol 9, Iss 3 (2023)
Objective The prevalence of comorbid chronic kidney disease (CKD) and osteoarthritis (OA) is increasing globally. While sharing common risk factors, the mechanism and consequences of concurrent CKD-OA are unclear. The aims of the study were to develo
Externí odkaz:
https://doaj.org/article/021c4b04613d4ee987918595fcef8583