Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexandra J. Van Ingelgom"'
Autor:
Na Zhao, Chia-Chen Liu, Alexandra J. Van Ingelgom, Cynthia Linares, Aishe Kurti, Joshua A. Knight, Michael G. Heckman, Nancy N. Diehl, Mitsuru Shinohara, Yuka A. Martens, Olivia N. Attrebi, Leonard Petrucelli, John D. Fryer, Zbigniew K. Wszolek, Neill R. Graff-Radford, Richard J. Caselli, Monica Y. Sanchez-Contreras, Rosa Rademakers, Melissa E. Murray, Shunsuke Koga, Dennis W. Dickson, Owen A. Ross, Guojun Bu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The APOE ε4 allele is a strong genetic risk factor for Alzheimer’s disease, whereas the APOE ε2 allele is protective. Here the authors show that mice expressing the human APOE ε2/ε2 genotype have increased tau pathology and related behavioral d
Externí odkaz:
https://doaj.org/article/47acaeff9b2f4fb58aa35f26dc4d2d72
Autor:
Mary D. Davis, Chia Chen Liu, Joshua Knight, Aishe Kurti, Fuyao Li, Guojun Bu, Cynthia Linares, Wenhui Qiao, John D. Fryer, Olivia N. Attrebi, Yingxue Ren, Marion Delenclos, Jiaying Zheng, Yan W. Asmann, Dennis W. Dickson, Pamela J. McLean, Owen A. Ross, Na Zhao, Francis Shue, Axel D. Meneses, Berkiye Sonustun, Yuka A. Martens, Yixing Chen, Alexandra J. Van Ingelgom
Publikováno v:
Sci Transl Med
The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease mainly by driving amyloid-β pathology. Recently, APOE4 has also been found to be a genetic risk factor for Lewy body dementia (LBD), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62676212be5002c8a8702f5c6ae0bc0
https://pubmed.ncbi.nlm.nih.gov/32107475
https://pubmed.ncbi.nlm.nih.gov/32107475
Autor:
Neill R. Graff-Radford, Na Zhao, Owen A. Ross, Zbigniew K. Wszolek, Richard J. Caselli, Joshua Knight, Guojun Bu, Nancy N. Diehl, Cynthia Linares, Olivia N. Attrebi, Melissa E. Murray, Mitsuru Shinohara, Chia Chen Liu, Dennis W. Dickson, John D. Fryer, Rosa Rademakers, Yuka A. Martens, Monica Sanchez-Contreras, Michael G. Heckman, Alexandra J. Van Ingelgom, Leonard Petrucelli, Shunsuke Koga, Aishe Kurti
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature communications
BASE-Bielefeld Academic Search Engine
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature communications
BASE-Bielefeld Academic Search Engine
Apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease mainly by modulating amyloid-β pathology. APOE ε4 is also shown to exacerbate neurodegeneration and neuroinflammation in a tau transgenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758af5de77182df0f0e2e93cecb3281e
http://europepmc.org/articles/PMC6197187
http://europepmc.org/articles/PMC6197187
Autor:
Chia Chen Liu, Joshua Knight, Alexandra J. Van Ingelgom, Meghan M. Painter, Na Zhao, Cynthia Linares, Guojun Bu, Yuka A. Martens, Patrick Sullivan
Publikováno v:
Neuron. 96:115-129.e5
Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer’s disease (AD). The association between diabetes and AD-associated amyloid pathology is stronger among carriers of the apolipoprotein E (APOE) ε4 gene allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8452f4694e53a166bca34e6b3a63f10f
https://doi.org/10.1016/j.neuron.2017.09.003
https://doi.org/10.1016/j.neuron.2017.09.003