Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexandra J, Croockewit"'
Autor:
Harm Westdorp, Jeroen H. A. Creemers, Inge M. van Oort, Gerty Schreibelt, Mark A. J. Gorris, Niven Mehra, Michiel Simons, Anna L. de Goede, Michelle M. van Rossum, Alexandra J. Croockewit, Carl G. Figdor, J. Alfred Witjes, Erik H. J. G. Aarntzen, Roel D. M. Mus, Mareke Brüning, Katja Petry, Martin Gotthardt, Jelle O. Barentsz, I. Jolanda M. de Vries, Winald R. Gerritsen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background Clinical benefit of cellular immunotherapy has been shown in patients with castration-resistant prostate cancer (CRPC). We investigated the immunological response and clinical outcome of vaccination with blood-derived CD1c+ myeloi
Externí odkaz:
https://doaj.org/article/4dc02aee961d45088f68d31ad80e605a
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
PDF file, 96K, Detection of tumor-specific T cells in SKIL cultures does not require challenge with defined epitopes. Tetramer analysis of SKILs cultured from biopsies of DTH reactions to DCs pulsed with tumor peptides (upper plots) or DCs electropor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b4ecc83c583c748182584f602a6fdd
https://doi.org/10.1158/1078-0432.22454442.v1
https://doi.org/10.1158/1078-0432.22454442.v1
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
Purpose: Electroporation of dendritic cells (DC) with mRNA encoding tumor-associated antigens (TAA) has multiple advantages compared to peptide loading. We investigated the immunologic and clinical responses to vaccination with mRNA-electroporated DC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f20607083d68d6b75c913531bcc4e
https://doi.org/10.1158/1078-0432.c.6522750.v1
https://doi.org/10.1158/1078-0432.c.6522750.v1
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
PDF file, 149K, CONSORT flow chart.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595a4d8dee7924abc9129d7e8cfd7422
https://doi.org/10.1158/1078-0432.22454448
https://doi.org/10.1158/1078-0432.22454448
Autor:
Gosse J. Adema, Cornelis J. A. Punt, Carl G. Figdor, I. Jolanda M. de Vries, Kris Thielemans, Roel Mus, Danita H. Schuurhuis, Tjitske Duiveman-de Boer, Joannes F. M. Jacobs, Willeke A. M. Blokx, Michelle M. van Rossum, Johannes H. W. de Wilt, Alexandra J. Croockewit, W. Joost Lesterhuis, Kalijn Bol, Gerty Schreibelt, Erik H. J. G. Aarntzen
PDF file, 1359K, Vaccine characteristics of first cycle of all patients. (A) Expression of HLA-ABC, HLA-DR/DP, HLA-DQ, CD80, CD86, CD83, and CCR7 was analyzed by flow cytometry. (B) Tumor antigen expression by DCs 2-4 hrs after electroporation with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9972bd46e8e67d96947535baab7380c
https://doi.org/10.1158/1078-0432.22454445
https://doi.org/10.1158/1078-0432.22454445
Autor:
Lieke L. van der Woude, W. Joost Lesterhuis, Winald R. Gerritsen, Martine Bloemendal, Cornelis J. A. Punt, Michelle M. van Rossum, Marieke E. B. Welzen, Winette T. A. van der Graaf, Stanleyson V. Hato, Erik H.J.G. Aarntzen, Nienke de Haas, Mark A.J. Gorris, Kalijn F. Bol, Steve Boudewijns, I. Jolanda M. de Vries, Carl G. Figdor, Rutger H. T. Koornstra, Gerty Schreibelt, Harm Westdorp, Alexandra J. Croockewit, Anna L. de Goede
Publikováno v:
Cancer Immunology, Immunotherapy
Cancer immunology, immunotherapy, 69(3), 477-488. Springer Science and Business Media Deutschland GmbH
Cancer Immunology Immunotherapy, 69, 477-488
Cancer Immunology Immunotherapy, 69, 3, pp. 477-488
Cancer immunology, immunotherapy, 69(3), 477-488. Springer Science and Business Media Deutschland GmbH
Cancer Immunology Immunotherapy, 69, 477-488
Cancer Immunology Immunotherapy, 69, 3, pp. 477-488
BackgroundAutologous dendritic cell (DC) vaccines can induce tumor-specific T cells, but their effect can be counteracted by immunosuppressive mechanisms. Cisplatin has shown immunomodulatory effects in vivo which may enhance efficacy of DC vaccinati
Autor:
Pieter Sonneveld, Meral Beksac, Bronno Van Der Holt, Meletios A Dimopoulos, Angelo Michele Carella, Heinz Ludwig, Sonja Zweegman, Thilo Zander, Ruth Wester, Roman Hajek, Lucia Pantani, Luca Dozza, Francesca Gay, Anna Maria Cafro, Luca De Rosa, Francesca Fioritoni, Ulf-Henrik Mellqvist, Rossella Troia, Niels Frost Andersen, Ka Lung Wu, Christoph Driessen, Susana Carvalho, Alexandra J. Croockewit, Fredrik Schjesvold, Massimo Offidani, Michele Cavo, Mario Boccadoro
Publikováno v:
Blood. 136:46-48
Background The role of consolidation treatment for newly diagnosed, transplant eligible MM (NDMM) patients has never been prospectively addressed in a randomised trial. Methods The EMN02/HOVON95 trial was designed to compare intensification therapy u
Autor:
Carl G. Figdor, Michelle M. van Rossum, Gerty Schreibelt, Jelle O. Barentsz, Inge M. van Oort, I. Jolanda M. de Vries, Alexandra J. Croockewit, Niven Mehra, Mark A.J. Gorris, J. Alfred Witjes, Michiel Simons, Erik H.J.G. Aarntzen, Harm Westdorp, Anna L. de Goede, Roel Mus, Mareke Brüning, Winald R. Gerritsen, Katja Petry, Martin Gotthardt, Jeroen H A Creemers
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Journal for Immunotherapy of Cancer, 7, 302
Journal for Immunotherapy of Cancer, 7, 1, pp. 302
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 7, 302
Journal for Immunotherapy of Cancer, 7, 1, pp. 302
Journal for Immunotherapy of Cancer
Contains fulltext : 215390pub.pdf (Publisher’s version ) (Open Access) Contains fulltext : 215390.pdf (Author’s version preprint ) (Open Access) BACKGROUND: Clinical benefit of cellular immunotherapy has been shown in patients with castration-res
Autor:
Pieter Sonneveld, Bronno van der Holt, Christine M. Segeren, Edo Vellenga, Alexandra J. Croockewit, Gregor E.G. Verhoef, Jan J. Cornelissen, Martijn R. Schaafsma, Marinus H.J. van Oers, Pierre W. Wijermans, Petra H.M. Westveer, Henk M. Lokhorst
Publikováno v:
Haematologica, Vol 92, Iss 7 (2007)
Background and Objectives The Dutch-Belgian HOVON group performed a randomized phase 3 trial to compare single non-myeloablative intensive treatment with double, intensive treatment in previously untreated patients with multiple myeloma (MM).Design a
Externí odkaz:
https://doaj.org/article/d70d7d0c55504bca96ffbccecc056912
Autor:
Liane te Boome, Georgine E. de Greef, Ellen P. A. Kramer, Cynthia Huisman, Yavuz M. Bilgin, Erik A M Beckers, Alexandra J. Croockewit, Otto Visser, Paula F. Ypma, Tanja Netelenbos
Publikováno v:
Transfusion. 55:1021-1027
BACKGROUND: Plerixafor in combination with granulocyte-colony-stimulating factor (G-CSF) is approved for the use of stem cell collection in patients who fail to mobilize on G-CSF. In 2009 the Stem Cell Working Party of the Dutch-Belgian Cooperative T