Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexandra Isabel Rosa"'
Autor:
Alexandra Isabel Rosa, Sofia Grade, Sofia Duque Santos, Liliana Bernardino, Thomas C Chen, João Relvas, Florence M Hofman, Fabienne Agasse
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
Neurogenesis in the subventricular zone (SVZ) is regulated by diffusible factors and cell-cell contacts. In vivo, SVZ stem cells are associated with the abluminal surface of blood vessels and such interactions are thought to regulate their neurogenic
Externí odkaz:
https://doaj.org/article/b1048b209ec0442d89ddd13aa67fdd81
Autor:
Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005328 (2015)
Notch signalling is a fundamental pathway that shapes the developing embryo and sustains adult tissues by direct communication between ligand and receptor molecules on adjacent cells. Among the ligands are two Delta paralogues, DLL1 and DLL4, that ar
Externí odkaz:
https://doaj.org/article/2ffcaf61c0d248b7a18b07854ece2d6f
Autor:
Maria João Gama, Maria João Nunes, Margarida Castro-Caldas, Elsa Rodrigues, Pedro A. Dionísio, Andreia Neves Carvalho, Cecília M. P. Rodrigues, Alexandra Isabel Rosa, Sara Duarte-Silva, Mariana Oliveira Mendes, Patrícia Maciel, Daniela Costa
Publikováno v:
Molecular and Cellular Neuroscience. 114:103626
Autor:
Elsa Rodrigues, Cecília M. P. Rodrigues, Sara Moreira, Maria João Nunes, Margarida Castro-Caldas, Maria João Gama, Andreia Neves Carvalho, Tiago F. Outeiro, Luísa Lemos, Alexandra Isabel Rosa, Inês T.E. Fonseca
Publikováno v:
Experimental Neurology. 295:77-87
Parkinson's disease (PD) is a progressive neurological disorder, mainly characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. Although the cause of PD remains elusive, mitochondrial dysfunction and severe oxidative
Autor:
Patrícia Maciel, Elsa Rodrigues, Sara Duarte-Silva, Andreia Neves Carvalho, Mariana Oliveira Mendes, Maria João Gama, Maria João Nunes, Cecília M. P. Rodrigues, Margarida Castro-Caldas, Alexandra Isabel Rosa, Pedro A. Dionísio, Daniela Costa
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Parkinson's disease (PD) is a progressive neurological disorder, mainly characterized by the progressive loss of dopaminergic neurons in the Substantia nigra pars compacta (SNpc) and by the presence of intracellular inclusions, known as Lewy bodies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebfe39a48f6564c038f99249bf4aa8a
Autor:
Alexandra Isabel Rosa, Andreia Neves Carvalho, Anabela Silva-Fernandes, Maria João Nunes, Patrícia Maciel, Margarida Castro-Caldas, Elsa Rodrigues, Maria João Gama, Cecília M. P. Rodrigues, Sara Duarte-Silva
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Parkinson's disease (PD) is characterized by severe motor symptoms, and currently there is no treatment that retards disease progression or reverses damage prior to the time of clinical diagnosis. Tauroursodeoxycholic acid (TUDCA) is neuroprotective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0d356aa607a3c097a44065b40e592c
https://hdl.handle.net/10362/114755
https://hdl.handle.net/10362/114755
Autor:
Liliana Bernardino, João O. Malva, Fabienne Agasse, Luísa Cortes, Joana Gonçalves, Alexandra Isabel Rosa
Publikováno v:
The Journal of Neuroscience. 30:4573-4584
In the adult mammalian brain, the subventricular zone (SVZ) hosts stem cells constantly generating new neurons. Angiopoietin-1 (Ang-1) is an endothelial growth factor with a critical role in division, survival, and adhesion of endothelial cells via T
Autor:
Adelaide Fernandes, Ana S. Falcão, Rui F.M. Silva, D. Allan Butterfield, Maria Alexandra Brito, Dora Brites, Alexandra Isabel Rosa
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 1, Pp 30-40 (2008)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
We investigated whether nerve cell damage by unconjugated bilirubin (UCB) is mediated by oxidative stress and ascertained the neuronal and astroglial susceptibility to injury. Several oxidative stress biomarkers and cell death were determined followi
Autor:
Alexandra Isabel Rosa, Karin Schuster-Gossler, Michael Stauber, Lena Tveriakhina, Domingos Henrique, Achim Gossler, Kristina Preuße, Cláudia Gaspar
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005328 (2015)
PLOS Genetics
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Genetics
PLOS Genetics
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Genetics
Copyright: © 2015 Preuße et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and s
Autor:
David P.D. Woldbye, Tiago Santos, Raquel Ferreira, Thomas Harnois, Liliana Bernardino, Laura Sardà-Arroyo, Nicolas Bourmeyster, Fabienne Agasse, José Bragança, Alexandra Isabel Rosa, João O. Malva, Søren H. Christiansen, Clarissa S. Schitine, Sara Xapelli, Valérie Coronas
Publikováno v:
Stem cells and development. 22(11)
Neural stem cells of the subventricular zone (SVZ) represent a potentially important source of surrogate cells for the treatment of brain damage. Proper use of these cells for neuronal replacement depends on the ability to drive neuronal differentiat