Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alexandra I. Thompson"'
Autor:
Stuart McPherson, Matthew J Armstrong, Jeremy F Cobbold, Lynsey Corless, Quentin M Anstee, Richard J Aspinall, Stephen T Barclay, Paul N Brennan, Tessa M Cacciottolo, Robert D Goldin, Kate Hallsworth, Vanessa Hebditch, Kathryn Jack, Helen Jarvis, Jill Johnson, Wenhao Li, Dina Mansour, Mary McCallum, Ashis Mukhopadhya, Richard Parker, Valerie Ross, Ian A Rowe, Ankur Srivastava, Prarthana Thiagarajan, Alexandra I Thompson, Jeremy Tomlinson, Emmanuel A Tsochatzis, Andrew Yeoman, William Alazawi
Publikováno v:
The Lancet Gastroenterology & Hepatology. 7:755-769
Non-alcoholic fatty liver disease (NAFLD) is common, affecting approximately 25% of the general population. The evidence base for the investigation and management of NAFLD is large and growing, but there is currently little practical guidance to supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30989b61d08fed024a6fc847f036cf2d
https://doi.org/10.1016/s2468-1253(22)00061-9
https://doi.org/10.1016/s2468-1253(22)00061-9
P19 Patient assessment and characteristics in a single-centre Fontan-associated liver disease cohort
Publikováno v:
Abstracts.
Background The Fontan operation is performed in individuals born with a single functional ventricle. The procedure separates venous return from the heart and allows normal arterial oxygen saturations. It extends the life span of these patients, who a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a8566f077a1c525d0e017dca72b9dd2
https://doi.org/10.1136/gutjnl-2020-basl.30
https://doi.org/10.1136/gutjnl-2020-basl.30
Autor:
John P. Iredale, Jacco Van Rheenen, Martin Lee, Kenneth J. Simpson, Alexandra I. Thompson, Kylie P. Conroy, Stephen N. Greenhalgh, Alan Serrels, Neil Henderson
Publikováno v:
Journal of Hepatology. 70:e378-e379
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6095b3e3376cf13ef2d8da95047b6e4a
https://doi.org/10.1016/s0618-8278(19)30742-x
https://doi.org/10.1016/s0618-8278(19)30742-x
Publikováno v:
Robertson, M, Thompson, A I & Hayes, P 2017, ' The management of bleeding from anorectal varices ', vol. 16, no. 4 . https://doi.org/10.1007/s11901-017-0382-6
The purpose of this review is to summarize available strategies for the diagnosis and management of bleeding anorectal varices. Interventional radiological procedures, including TIPS, BRTO and/or embolization, have been established as efficacious tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a9334cb5987ca1510120a752bcc2eb
https://hdl.handle.net/20.500.11820/d15ad97b-50d2-408f-8dc4-340eb4ec28f9
https://hdl.handle.net/20.500.11820/d15ad97b-50d2-408f-8dc4-340eb4ec28f9
Autor:
Zara Hannoun, Claire N. Medine, Sebastian Greenhough, John P. Iredale, Salvatore Pernagallo, Mark Bradley, James A. Ross, Judy Fletcher, James R. Black, Alexandra I. Thompson, Juan J. Díaz-Mochón, Donna Dalgetty, Joerg Schrader, Stuart J. Forbes, David C. Hay, Philip N. Newsome
Publikováno v:
Stem Cell Research. 6(2):92-102
Maintaining stable differentiated somatic cell function in culture is essential to a range of biological endeavors. However, current technologies, employing, for example, primary hepatic cell culture (essential to the development of a bio-artificial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9017e6c999f57faa2ba90afcc1f70b
Autor:
Charlie W. Lees, Alexandra I. Thompson
Publikováno v:
Inflammatory Bowel Diseases. 17:831-848
Ulcerative colitis (UC) and Crohn's disease (CD) are related polygenic inflammatory bowel diseases (IBDs), with distinct and overlapping susceptibility loci. Recently, hypothesis-free genome-wide association (GWA) studies have revolutionized the fiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be64673a115f5d68bf81dd308d702a6
https://doi.org/10.1002/ibd.21375
https://doi.org/10.1002/ibd.21375
Autor:
J Fennell, Alan G. Shand, David C. Wilson, P Rogers, Rachael O. Forsythe, Stuart Aitken, I. D. R. Arnott, Alexandra I. Thompson, Ian D. Penman, Charlie W. Lees, Gwo-Tzer Ho, K. R. Palmer, A. I. Ali, Jack Satsangi, L. Marquez, C. J. Cochrane
Publikováno v:
Alimentary Pharmacology & Therapeutics. 29:286-297
Summary Background Anti-TNF agents are now widely used in Crohn’s disease (CD), and in ulcerative colitis (UC). Aim To review the safety profile of anti-TNF agents in all patients treated with infliximab in Edinburgh from 1999 to 2007. Methods Comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb73266925bfcccb9f3680182e945b7e
https://doi.org/10.1111/j.1365-2036.2008.03882.x
https://doi.org/10.1111/j.1365-2036.2008.03882.x
Autor:
Neil C. Henderson, D G Craig, Andrea Caporali, Laura E J Peeters, Kenneth J. Simpson, Jonathan M Shaffer, A. D. B. Vliegenthart, Alexandra I. Thompson, Joanna I. Clarke, David J. Webb, Joanna Moore, James W. Dear, Jack Sharkey, Eric Lader, B.K. Park, D. N. Bateman, Paul I. Dargan, Matthew A. Bailey, D.J. Antoine, David M. Wood
Publikováno v:
Scientific Reports
Vliegenthart, A D B, Shaffer, J M, Clarke, J I, Peeters, L E J, Caporali, A, Bateman, D N, Wood, D M, Dargan, P I, Craig, D G, Moore, J K, Thompson, A I, Henderson, N C, Webb, D J, Sharkey, J, Antoine, D J, Park, B K, Bailey, M A, Lader, E, Simpson, K & Dear, J W 2015, ' Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury ', Scientific Reports, vol. 5, pp. 15501 . https://doi.org/10.1038/srep15501
Vliegenthart, A D B, Shaffer, J M, Clarke, J I, Peeters, L E J, Caporali, A, Bateman, D N, Wood, D M, Dargan, P I, Craig, D G, Moore, J K, Thompson, A I, Henderson, N C, Webb, D J, Sharkey, J, Antoine, D J, Park, B K, Bailey, M A, Lader, E, Simpson, K & Dear, J W 2015, ' Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury ', Scientific Reports, vol. 5, pp. 15501 . https://doi.org/10.1038/srep15501
Our objective was to identify microRNA (miRNA) biomarkers of drug-induced liver and kidney injury by profiling the circulating miRNome in patients with acetaminophen overdose. Plasma miRNAs were quantified in age- and sex-matched overdose patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb470e32852d05c62c02f667bbc9359
Publikováno v:
Thompson, A I, Conroy, K P & Henderson, N C 2015, ' Hepatic stellate cells : central modulators of hepatic carcinogenesis ', BMC gastroenterology, vol. 15, pp. 63 . https://doi.org/10.1186/s12876-015-0291-5
BMC Gastroenterology
BMC Gastroenterology
Hepatocellular carcinoma (HCC) represents the second most common cause of cancer-related death worldwide, and is increasing in incidence. Currently, our therapeutic repertoire for the treatment of HCC is severely limited, and therefore effective new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80918949fac2400dd3cc3c22460cddd
https://www.pure.ed.ac.uk/ws/files/20045990/Hepatic_stellate_cells.pdf
https://www.pure.ed.ac.uk/ws/files/20045990/Hepatic_stellate_cells.pdf
Publikováno v:
Oxidative Stress in Applied Basic Research and Clinical Practice ISBN: 9783319155388
The inflammatory response is of prime importance in liver disease, irrespective of inciting cause, and is inextricably linked to oxidative stress and the generation of reactive oxygen species (ROS). During the inflammatory response, ROS in Kupffer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54e141de4a28dfe49fe08e58dd021741
https://doi.org/10.1007/978-3-319-15539-5_6
https://doi.org/10.1007/978-3-319-15539-5_6