Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Alexandra I. Soto‐Beasley"'
Autor:
Shunsuke Koga, Aya Murakami, Alexandra I. Soto-Beasley, Ronald L. Walton, Matthew C. Baker, Monica Castanedes-Casey, Keith A. Josephs, Owen A. Ross, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Frontotemporal lobar degeneration (FTLD) is a group of disorders characterized by degeneration of the frontal and temporal lobes, leading to progressive decline in language, behavior, and motor function. FTLD can be further subdivided into t
Externí odkaz:
https://doaj.org/article/ac89a41380b2423b8c85b9f8a0592b72
Autor:
Shunsuke Koga, Michael A. Metrick, Lawrence I. Golbe, Alessia Santambrogio, Minji Kim, Alexandra I. Soto-Beasley, Ronald L. Walton, Matthew C. Baker, Cristhoper Fernandez De Castro, Michael DeTure, David Russell, Bradford A. Navia, Christine Sandiego, Owen A. Ross, Michele Vendruscolo, Byron Caughey, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are distinct clinicopathological subtypes of frontotemporal lobar degeneration. They both have atypical parkinsonism, and they usually have distinct clinical features.
Externí odkaz:
https://doaj.org/article/5b670a275ffd416fa2fba930681c881b
Autor:
Rebecca R. Valentino, Chloe Ramnarine, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Koji Kasanuki, Melissa E. Murray, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin-Taner, Rodolfo Savica, Jonathan Graff-Radford, Ronald C. Petersen, Joseph E. Parisi, R. Ross Reichard, Neill R. Graff-Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Dementia with Lewy bodies (DLB) is clinically diagnosed when patients develop dementia less than a year after parkinsonism onset. Age is the primary risk factor for DLB and mitochondrial health influences ageing through effective oxidative p
Externí odkaz:
https://doaj.org/article/3ccebbf408344276a4d599bfa2266e82
Autor:
Shunsuke Koga, Aya Murakami, Alexandra I. Soto-Beasley, Ronald L. Walton, Matthew C. Baker, Monica Castanedes-Casey, Keith A. Josephs, Owen A. Ross, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/22aa5abb71504c85ae64ae258edf3eac
Autor:
Diana A. Olszewska, Allan McCarthy, Alexandra I. Soto-Beasley, Ronald L. Walton, Owen A. Ross, Tim Lynch
Publikováno v:
Journal of Movement Disorders, Vol 15, Iss 1, Pp 83-85 (2022)
Externí odkaz:
https://doaj.org/article/50c67ce1d13f463d997c0f5e67e306cb
Autor:
Rebecca R. Valentino, Shunsuke Koga, Ronald L. Walton, Alexandra I. Soto-Beasley, Naomi Kouri, Michael A. DeTure, Melissa E. Murray, Patrick W. Johnson, Ronald C. Petersen, Bradley F. Boeve, Ryan J. Uitti, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross, Michael G. Heckman
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-9 (2020)
Abstract The microtubule-associated protein tau (MAPT) H1 haplotype is the strongest genetic risk factor for corticobasal degeneration (CBD). However, the specific H1 subhaplotype association is not well defined, and it is not clear whether any MAPT
Externí odkaz:
https://doaj.org/article/5fc49e4942314738a9faeede291c7e80
Autor:
Angela B. Deutschlander, Takuya Konno, Alexandra I. Soto‐Beasley, Ronald L. Walton, Jay A. vanGerpen, Ryan J. Uitti, Michael G. Heckman, Zbigniew K. Wszolek, Owen A. Ross
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1557-1563 (2020)
Abstract Objective To determine whether distinct microtubule‐associated protein tau MAPT H1 subhaplotypes are associated with clinical and demographic features in Parkinson’s disease. Methods A retrospective cohort study included 855 unrelated Ca
Externí odkaz:
https://doaj.org/article/eec7aa4a232c4597b7bd767393b8c22b
Autor:
Rebecca R. Valentino, Nikoleta Tamvaka, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Ryan J. Uitti, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract Mitochondrial health is important in ageing and dysfunctional oxidative phosphorylation (OXPHOS) accelerates ageing and influences neurodegeneration. Mitochondrial DNA (mtDNA) codes for vital OXPHOS subunits and mtDNA background has been ass
Externí odkaz:
https://doaj.org/article/41a930b15db74bc3bbf3b57ab6921724
Autor:
Benjamin J. Broadway, Paige K. Boneski, Jenny M. Bredenberg, Ana Kolicheski, Xu Hou, Alexandra I. Soto-Beasley, Owen A. Ross, Wolfdieter Springer, Fabienne C. Fiesel
Publikováno v:
Cells, Vol 11, Iss 15, p 2426 (2022)
Loss of either PINK1 or PRKN causes an early onset Parkinson’s disease (PD) phenotype. Functionally, PINK1 and PRKN work together to mediate stress-activated mitochondrial quality control. Upon mitochondrial damage, PINK1, a ubiquitin kinase and PR
Externí odkaz:
https://doaj.org/article/745458ca5f5e4e5aaaecae28887ee189
Autor:
Lukasz M. Milanowski, Olajumoke Oshinaike, Benjamin J. Broadway, Jennifer A. Lindemann, Alexandra I. Soto-Beasley, Ronald L. Walton, Rana Hanna Al-Shaikh, Audrey J. Strongosky, Fabienne C. Fiesel, Owen A. Ross, Wolfdieter Springer, Shamsideen Abayomi Ogun, Zbigniew K. Wszolek
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Introduction: Nigeria is one of the most populated countries in the world; however, there is a scarcity of studies in patients with age-related neurodegenerative diseases, such as Parkinson disease (PD). The aim of this study was to screen patients w
Externí odkaz:
https://doaj.org/article/53171b24c12d4f2ea92cd65fbb54a435