Výsledky vyhledávání - "Alexandra Hickman"

Therapies for head and neck squamous cell carcinoma (HNSCC) are, at best, moderately effective, underscoring the need for new therapeutic strategies. Ceramide treatment leads to cell death as a consequence of mitochondrial damage by generating oxidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e9505519539f89dd00230139069196
https://doi.org/10.1158/1535-7163.c.6542178

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Supplemental Table 1 from Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome–Induced Cell Death in Head and Neck Squamous Cell Carcinoma

Inhibitors and Inducers of Autophagy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f892e467e660f8b88fcf8f61ded1f8e
https://doi.org/10.1158/1535-7163.22518906

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Supplemental Figure 3 from Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome–Induced Cell Death in Head and Neck Squamous Cell Carcinoma

Methylpyruvate Partially Rescues from CNL+CQ-driven Autophagic/Mitophagic Response in UNC-10 Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80461fa334c9112bdd3647bab301271b
https://doi.org/10.1158/1535-7163.22518912

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Supplemental Figure 4 from Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome–Induced Cell Death in Head and Neck Squamous Cell Carcinoma

Methylpyruvate Rescues from CNL+CQ-driven Oxidative Stress and Mitochondrial Function in UNC-10 Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143a4252c64fb91518fa16bb5311b1e3
https://doi.org/10.1158/1535-7163.22518909.v1

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Supplemental Figure 1 from Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome–Induced Cell Death in Head and Neck Squamous Cell Carcinoma

IC50 Values of CNL-Induced Decreases in Cell Viability at 48 hours in Seven HNSCC Cell Lines and Non-Transformed PGF Cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634037b3eb33874e706fa235dfc8bc15
https://doi.org/10.1158/1535-7163.22518918

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Characterization and comparison of innate and adaptive immune responses at vaccine sites in melanoma vaccine clinical trials

Autor: Marit M, Melssen, Karlyn E, Pollack, Max O, Meneveau, Mark E, Smolkin, Joel, Pinczewski, Alexander F, Koeppel, Stephen D, Turner, Katia, Sol-Church, Alexandra, Hickman, Donna H, Deacon, Gina R, Petroni, Craig L, Slingluff

Publikováno v: Cancer immunology, immunotherapy : CII. 70(8)

The strength and durability of systemic anti-tumor immune responses induced by cancer vaccines depends on adjuvants to support an immunogenic vaccine site microenvironment (VSME). Adjuvants include water-in-oil emulsions with incomplete Freund's adju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d6e262a1f7f0fd682ff8fd8de03e2665
https://pubmed.ncbi.nlm.nih.gov/33454795

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