Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexandra Helleux"'
Autor:
Bujamin H. Vokshi, Guillaume Davidson, Nassim Tawanaie Pour Sedehi, Alexandra Helleux, Marc Rippinger, Alexandre R. Haller, Justine Gantzer, Jonathan Thouvenin, Philippe Baltzinger, Rachida Bouarich, Valeria Manriquez, Sakina Zaidi, Priya Rao, Pavlos Msaouel, Xiaoping Su, Hervé Lang, Thibault Tricard, Véronique Lindner, Didier Surdez, Jean-Emmanuel Kurtz, Franck Bourdeaut, Nizar M. Tannir, Irwin Davidson, Gabriel G. Malouf
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Renal medullary carcinoma (RMC) is an aggressive tumour driven by bi-allelic loss of SMARCB1 and tightly associated with sickle cell trait. However, the cell-of-origin and oncogenic mechanism remain poorly understood. Using single-cell seque
Externí odkaz:
https://doaj.org/article/01f90a34514d4d2a88792568e2a609ad
Autor:
Bjorn Thor Adalsteinsson, Thordis Kristjansdottir, William Merre, Alexandra Helleux, Julia Dusaucy, Mathilde Tourigny, Olafur Fridjonsson, Gudmundur Oli Hreggvidsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Thermophilic organisms are extensively studied in industrial biotechnology, for exploration of the limits of life, and in other contexts. Their optimal growth at high temperatures presents a challenge for the development of genetic tools for
Externí odkaz:
https://doaj.org/article/71aa805bce4a4201afdca651fc406aba
Autor:
Susanna Säisä-Borreill, Guillaume Davidson, Thomas Kleiber, Andréa Thevenot, Elisabeth Martin, Stanislas Mondot, Hervé Blottière, Alexandra Helleux, Gabrielle Mengus, Michelina Plateroti, Isabelle Duluc, Irwin Davidson, Jean-Noel Freund
Publikováno v:
Cell Death & Differentiation. 30:839-853
Taf4 (TATA-box binding protein-associated factor 4) is a subunit of the general transcription factor TFIID, a component of the RNA polymerase II pre-initiation complex that interacts with tissue-specific transcription factors to regulate gene express
Autor:
Xiaofan Lu, Yann Vano, Alexandra Helleux, Xiaoping Su, Véronique Lindner, Guillaume Davidson, Roger Mouawad, Jean-Philippe Spano, Morgan Rouprêt, Reza Elaidi, Eva Compérat, Virginie Verkarre, Chengming Sun, Christine Chevreau, Mostefa Bennamoun, Hervé Lang, Thibault Tricard, Wenxuan Cheng, Li Xu, Irwin Davidson, Fangrong Yan, Wolf Herman Fridman, Catherine Sautes-Fridman, Stéphane Oudard, Gabriel G. Malouf
Publikováno v:
Clinical Cancer Research. 29:1279-1291
Purpose: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of patients with clear-cell renal cell carcinomas (ccRCC). Although analyses of transcriptome, genetic alterations, and the tumor microenvironment (TME) have shed light int
Autor:
Gabriel G. Malouf, Stéphane Oudard, Catherine Sautes-Fridman, Wolf Herman Fridman, Fangrong Yan, Irwin Davidson, Li Xu, Wenxuan Cheng, Thibault Tricard, Hervé Lang, Mostefa Bennamoun, Christine Chevreau, Chengming Sun, Virginie Verkarre, Eva Compérat, Reza Elaidi, Morgan Rouprêt, Jean-Philippe Spano, Roger Mouawad, Guillaume Davidson, Véronique Lindner, Xiaoping Su, Alexandra Helleux, Yann Vano, Xiaofan Lu
Purpose:Immune checkpoint inhibitors (ICI) have revolutionized the treatment of patients with clear-cell renal cell carcinomas (ccRCC). Although analyses of transcriptome, genetic alterations, and the tumor microenvironment (TME) have shed light into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d565608e16d885770979fdf98b23e457
https://doi.org/10.1158/1078-0432.c.6532839
https://doi.org/10.1158/1078-0432.c.6532839
Autor:
Gabriel G. Malouf, Stéphane Oudard, Catherine Sautes-Fridman, Wolf Herman Fridman, Fangrong Yan, Irwin Davidson, Li Xu, Wenxuan Cheng, Thibault Tricard, Hervé Lang, Mostefa Bennamoun, Christine Chevreau, Chengming Sun, Virginie Verkarre, Eva Compérat, Reza Elaidi, Morgan Rouprêt, Jean-Philippe Spano, Roger Mouawad, Guillaume Davidson, Véronique Lindner, Xiaoping Su, Alexandra Helleux, Yann Vano, Xiaofan Lu
Figure S2. Focal copy number deletion identified by the GISTIC algorithm for a) 𝑇𝐸𝐷+ and b) 𝑇𝐸𝐷−, respectively, in the TCGA-KIRC cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fcf5cf8adfb56e1748fafb0760265b
https://doi.org/10.1158/1078-0432.22494933
https://doi.org/10.1158/1078-0432.22494933
Autor:
Gabriel G. Malouf, Stéphane Oudard, Catherine Sautes-Fridman, Wolf Herman Fridman, Fangrong Yan, Irwin Davidson, Li Xu, Wenxuan Cheng, Thibault Tricard, Hervé Lang, Mostefa Bennamoun, Christine Chevreau, Chengming Sun, Virginie Verkarre, Eva Compérat, Reza Elaidi, Morgan Rouprêt, Jean-Philippe Spano, Roger Mouawad, Guillaume Davidson, Véronique Lindner, Xiaoping Su, Alexandra Helleux, Yann Vano, Xiaofan Lu
Supplementary Tables S1-S23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68ff291fc643ecd8eeabdb1d73045e5
https://doi.org/10.1158/1078-0432.22488930
https://doi.org/10.1158/1078-0432.22488930
Autor:
Gabriel Malouf, Xiaofan Lu, Yann Vano, Alexandra Helleux, Xiaoping Su, Véronique Lindner, Guillaume Davidson, Roger Mouawad, Jean-Philippe Spano, Morgan Rouprêt, Reza Elaidi, Eva Compérat, Virginie Verkarre, Chengming Sun, Christine Chevreau, Mostefa Bennamoun, Hervé Lang, Thibault Tricard, Wenxuan Cheng, Li Xu, Irwin Davidson, Fangrong Yan, Wolf FRIDMAN, Catherine Sautès-Fridman, Stéphane Oudard
Immune checkpoint inhibitors have revolutionized the treatment of patients with clear-cell renal carcinomas. Although, analyses of transcriptome, genetic alterations, and the tumor microenvironment have shed light into mechanisms of response and resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ba383af6abe0a5fc4581f18492e2fe8
https://doi.org/10.21203/rs.3.rs-1673570/v1
https://doi.org/10.21203/rs.3.rs-1673570/v1
Autor:
Bujamin Vokshi, Guillaume Davidson, Alexandra Helleux, Marc Rippinger, Alexandre Haller, Justine Gantzer, Philippe Baltzinger, Jonathan Thouvenin, Rachida Bouarich-Bourimi, Valentina Manriquez, Sakina Zaidi, Pavlos Msaouel, Xiaoping Su, Hervé Lang, Thibault Tricard, Véronique Lindner, Didier Surdez, Jean-Emmanuel Kurtz, Franck BOURDEAUT, Nizar Tannir, Irwin Davidson, Gabriel Malouf
Renal medullary carcinoma (RMC) is an aggressive tumour driven by bi-allelic loss of SMARCB1 and tightly associated with sickle cell trait. However, the cell-of-origin and oncogenic mechanism remain poorly understood. Using single-cell sequencing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5a58b6653320a21103a472808302ca
https://doi.org/10.21203/rs.3.rs-1178801/v1
https://doi.org/10.21203/rs.3.rs-1178801/v1
We developed a simplified, highly efficient Gateway reaction that recombines target DNA to expression (destination) plasmids in vivo and subsequently conjugates the final vector into a recipient strain, all in a single step. This recipient strain doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe53a3b136503a7ff998c7eee066ad9
https://hdl.handle.net/10037/23307
https://hdl.handle.net/10037/23307