Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexandra Hebar"'
Autor:
Alexandra Hebar, Christiane Koller, Jan-Marcus Seifert, Monika Chabicovsky, Angelika Bodenteich, Andreas Bernkop-Schnürch, Andreas Grassauer, Eva Prieschl-Grassauer
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122911 (2015)
Carrageenan has been widely used as food additive for decades and therefore, an extended oral data set is available in the public domain. Less data are available for other routes of administration, especially intranasal administration. The current pu
Externí odkaz:
https://doaj.org/article/db3ca29dfd7e43558ebd00c137d2fa53
Autor:
Katharina Proestling, Alexandra Hebar, Nina Pruckner, Erika Marton, Ursula Vinatzer, Martin Schreiber
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47325 (2012)
BACKGROUND: The TP53 Arg72Pro polymorphism encodes two p53 variants with different biochemical properties. Here we investigated the impact of this polymorphism on the expression of key p53 target genes in a panel of human breast carcinomas, breast ca
Externí odkaz:
https://doaj.org/article/426a256e0abf47bf823e5e2af510f2d9
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45015 (2012)
The new molecular entity quinoxalinhydrazide derivative NVX-412 was identified as a promising drug candidate for the treatment of various cancer types due to its strong cytotoxic activity and relative specificity. Here, we provide first data about th
Externí odkaz:
https://doaj.org/article/6416bbfe2cc8453d8cc3d20413f7937f
Publikováno v:
Expert Review of Clinical Pharmacology. 6:23-34
The last decades were characterized by enormous technological advances resulting in a better understanding of disease pathologies and improvement of treatment strategies. The development of targeted drugs, whose beginning can be traced back to Paul E
Autor:
Otto Doblhoff-Dier, Thomas Muster, Monika Chabicovsky, Oliver H. J. Szolar, Joachim Seipelt, Alexandra Hebar, Eva Prieschl-Grassauer
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 107:758-767
Pyrrolidine dithiocarbamate (PDTC) was examined for its potential in the intranasal treatment of human rhinovirus infections. Prior to clinical testing, a comprehensive non-clinical programme was performed to evaluate the general toxicity of PDTC. Th
Autor:
Andreas Bernkop-Schnürch, Angelika Bodenteich, Alexandra Hebar, Jan-Marcus Seifert, Monika Chabicovsky, Andreas Grassauer, Eva Prieschl-Grassauer, Christiane Koller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0122911 (2015)
PLoS ONE, Vol 10, Iss 4, p e0122911 (2015)
Carrageenan has been widely used as food additive for decades and therefore, an extended oral data set is available in the public domain. Less data are available for other routes of administration, especially intranasal administration. The current pu
Autor:
Thomas W, Grunt, Alexandra, Hebar, Sylvia, Laffer, Renate, Wagner, Barbara, Peter, Harald, Herrmann, Alexandra, Graf, Martin, Bilban, Martin, Posch, Gregor, Hoermann, Matthias, Mayerhofer, Gregor, Eisenwort, Christoph C, Zielinski, Edgar, Selzer, Peter, Valent
Publikováno v:
American journal of cancer research. 5(2)
Advanced colorectal cancer is characterized by uncontrolled growth and resistance against anti-cancer agents, including ErbB inhibitors. Recent data suggest that cancer stem cells (CSC) are particularly resistant. These cells may reside within a CD13
Autor:
Alexandra Hebar, Edgar Selzer
Publikováno v:
Wiener medizinische Wochenschrift (1946). 162(3-4)
In order to understand the consequences of radiation a thorough understanding of the radiobiological mechanisms of the molecular up to the clinical level is of importance. Radiobiology therefore combines the basic principles of physics as well as bio
Autor:
Monika, Chabicovsky, Eva, Prieschl-Grassauer, Joachim, Seipelt, Thomas, Muster, Oliver H J, Szolar, Alexandra, Hebar, Otto, Doblhoff-Dier
Publikováno v:
Basicclinical pharmacologytoxicology. 107(3)
Pyrrolidine dithiocarbamate (PDTC) was examined for its potential in the intranasal treatment of human rhinovirus infections. Prior to clinical testing, a comprehensive non-clinical programme was performed to evaluate the general toxicity of PDTC. Th
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45015 (2012)
PLoS ONE
PLoS ONE
The new molecular entity quinoxalinhydrazide derivative NVX-412 was identified as a promising drug candidate for the treatment of various cancer types due to its strong cytotoxic activity and relative specificity. Here, we provide first data about th