Microtissues from mesenchymal stem cells and siRNA-loaded cross-linked gelatin microparticles for bone regeneration

Autor: Sandra Hinkelmann, Alexandra H. Springwald, Annett Starke, Hermann Kalwa, Christian Wölk, Michael C. Hacker, Michaela Schulz-Siegmund

Publikováno v: Materials Today Bio, Vol 13, Iss , Pp 100190- (2022)

The aim of this study was the evaluation of cross-linked gelatin microparticles (cGM) as substrates for osteogenic cell culture to assemble 3D microtissues and their use as delivery system for siRNA to cells in these assemblies.In a 2D transwell cult

Externí odkaz: https://doaj.org/article/aa7736821e854c35959eb81215a15189

Dual-Component Gelatinous Peptide/Reactive Oligomer Formulations as Conduit Material and Luminal Filler for Peripheral Nerve Regeneration

Autor: Caroline Kohn-Polster, Sandra Franz, Annett Starke, Joachim Kohn, Hilton M. Kaplan, Divya Bhatnagar, Alexandra H Springwald, Michaela Schulz-Siegmund, Derek J Woloszyn, Michael C. Hacker, Matthew Richtmyer

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 5, p 1104 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 5; Pages: 1104

Toward the next generation of nerve guidance conduits (NGCs), novel biomaterials and functionalization concepts are required to address clinical demands in peripheral nerve regeneration (PNR). As a biological polymer with bioactive motifs, gelatinous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a062bf6766f882c52bfce0080084ec
http://www.mdpi.com/1422-0067/18/5/1104