Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexandra H. Besser"'
Autor:
Fiona Simpkins, Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Wei Gao, Patricia Brafford, Gao Zhang, Zhi Wei, Mengnan Gu, Tan A. Ince, Alexandra H. Besser, Jun Sun, Dorraya El-Ashry, Philip C. Miller, Karina E. Hew
Supplementary Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bb84eead8700009de554900f61f323
https://doi.org/10.1158/1078-0432.22461041.v1
https://doi.org/10.1158/1078-0432.22461041.v1
Autor:
Fiona Simpkins, Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Wei Gao, Patricia Brafford, Gao Zhang, Zhi Wei, Mengnan Gu, Tan A. Ince, Alexandra H. Besser, Jun Sun, Dorraya El-Ashry, Philip C. Miller, Karina E. Hew
Purpose: Although 67% of high-grade serous ovarian cancers (HGSOC) express the estrogen receptor (ER), most fail antiestrogen therapy. Because MAPK activation is frequent in ovarian cancer, we investigated if estrogen regulates MAPK and if MEK inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3140986ec653370b0b3a08c01480ac
https://doi.org/10.1158/1078-0432.c.6524681
https://doi.org/10.1158/1078-0432.c.6524681
Autor:
Fiona Simpkins, Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Wei Gao, Patricia Brafford, Gao Zhang, Zhi Wei, Mengnan Gu, Tan A. Ince, Alexandra H. Besser, Jun Sun, Dorraya El-Ashry, Philip C. Miller, Karina E. Hew
Supplementary Figure 1. (A) Percent of HGSOCs from the TCGA cohort with mutations in 42 genes associated with the RAS/Raf/MEK/MAPK pathway (N=45/311); (B) Percent of HGSOCs from the TCGA cohort with copy number amplifications or mRNA overexpression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d1a7224b330419a1435cd90e157ef5
https://doi.org/10.1158/1078-0432.22461044.v1
https://doi.org/10.1158/1078-0432.22461044.v1
Autor:
Joyce M. Slingerland, Juan A. Marchal, Pablo Torné-Poyatos, Dorraya El-Ashry, Guy A. Howard, Richard J. Cote, Ram H. Datar, Burcu Ergonul, Bin Wang, Seth A. Wander, Diana J. Azzam, Tan A. Ince, Minsoon Kim, Cynthia Morata-Tarifa, Dekuang Zhao, Alexandra H. Besser, Kibeom Jang, Katherine Drews-Elger, Chendong Pan, Manuel Picon-Ruiz
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a4662e24af0c21e76bb5b675a0426a
https://doi.org/10.1158/0008-5472.22408617
https://doi.org/10.1158/0008-5472.22408617
Autor:
Joyce M. Slingerland, Juan A. Marchal, Pablo Torné-Poyatos, Dorraya El-Ashry, Guy A. Howard, Richard J. Cote, Ram H. Datar, Burcu Ergonul, Bin Wang, Seth A. Wander, Diana J. Azzam, Tan A. Ince, Minsoon Kim, Cynthia Morata-Tarifa, Dekuang Zhao, Alexandra H. Besser, Kibeom Jang, Katherine Drews-Elger, Chendong Pan, Manuel Picon-Ruiz
Consequences of the obesity epidemic on cancer morbidity and mortality are not fully appreciated. Obesity is a risk factor for many cancers, but the mechanisms by which it contributes to cancer development and patient outcome have yet to be fully elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa20f08db337200792380387f3be39ff
https://doi.org/10.1158/0008-5472.c.6507570.v1
https://doi.org/10.1158/0008-5472.c.6507570.v1
Autor:
Joyce M. Slingerland, Juan A. Marchal, Pablo Torné-Poyatos, Dorraya El-Ashry, Guy A. Howard, Richard J. Cote, Ram H. Datar, Burcu Ergonul, Bin Wang, Seth A. Wander, Diana J. Azzam, Tan A. Ince, Minsoon Kim, Cynthia Morata-Tarifa, Dekuang Zhao, Alexandra H. Besser, Kibeom Jang, Katherine Drews-Elger, Chendong Pan, Manuel Picon-Ruiz
hASC characterization (S1); Co-culture of immature adipocytes with mammary epithelial cells increases pro-inflammatory cytokine expression (S2); Immature adipocyte or cytokine exposure increases abundance of sphere and colony forming cells without ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1494ea3cd72106e731ec0263fc37fa98
https://doi.org/10.1158/0008-5472.22408620
https://doi.org/10.1158/0008-5472.22408620
Autor:
Alexandra H. Besser, Lauren K. Fang, Michelle W. Tong, Maren M. Sjaastad Andreassen, Haydee Ojeda-Fournier, Christopher C. Conlin, Stéphane Loubrie, Tyler M. Seibert, Michael E. Hahn, Joshua M. Kuperman, Anne M. Wallace, Anders M. Dale, Ana E. Rodríguez-Soto, Rebecca A. Rakow-Penner
Publikováno v:
Cancers
Cancers, vol 14, iss 13
Cancers; Volume 14; Issue 13; Pages: 3200
Cancers, vol 14, iss 13
Cancers; Volume 14; Issue 13; Pages: 3200
Diffusion-weighted MRI (DW-MRI) offers a potential adjunct to dynamic contrast-enhanced MRI to discriminate benign from malignant breast lesions by yielding quantitative information about tissue microstructure. Multi-component modeling of the DW-MRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ea7ac9609289b176720b60030258c0
https://hdl.handle.net/11250/3044314
https://hdl.handle.net/11250/3044314
Publikováno v:
Retson, Tara A; Besser, Alexandra H; Sall, Sean; Golden, Daniel; & Hsiao, Albert. (2019). Machine Learning and Deep Neural Networks in Thoracic and Cardiovascular Imaging.. Journal of thoracic imaging, 34(3), 192-201. doi: 10.1097/rti.0000000000000385. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6kb012qf
Journal of thoracic imaging, vol 34, iss 3
J Thorac Imaging
Journal of thoracic imaging, vol 34, iss 3
J Thorac Imaging
Advances in technology have always had the potential and opportunity to shape the practice of medicine, and in no medical specialty has technology been more rapidly embraced and adopted than radiology. Machine learning and deep neural networks promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61202f0001964bd9133c6dcf571489e
http://www.escholarship.org/uc/item/6kb012qf
http://www.escholarship.org/uc/item/6kb012qf
Autor:
Kibeom Jang, Joyce M. Slingerland, Xue Xiao, Minsoon Kim, Seth A. Wander, Alexandra H. Besser, Karoline J. Briegel, Hyunho Yoon, Miyoung Shin, Andy J. Minn, Dekuang Zhao, Lluis Morey
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(14)
p27 shifts from CDK inhibitor to oncogene when phosphorylated by PI3K effector kinases. Here, we show that p27 is a cJun coregulator, whose assembly and chromatin association is governed by p27 phosphorylation. In breast and bladder cancer cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6289b5975e7c6e895a5989b5c2dec4df
https://pubmed.ncbi.nlm.nih.gov/31689160
https://pubmed.ncbi.nlm.nih.gov/31689160
Autor:
Tae Kyoung Kwak, Marc E. Lippman, Alexandra H. Besser, Dekuang Zhao, Joyce M. Slingerland, Barry I. Hudson, Katherine Drews-Elger, Ayse Ergonul
Publikováno v:
Cancer Research. 76:P2-05
Breast cancer is most common malignant state in women, with 20% of these patients developing metastasis during the course of their disease. Further understanding is needed of the process and mechanisms of metastasis. Our lab and others have been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f981070133227cfc548d5632271db2c2
https://doi.org/10.1158/1538-7445.sabcs15-p2-05-07
https://doi.org/10.1158/1538-7445.sabcs15-p2-05-07