Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexandra Gouasmat"'
Autor:
Tohru Yamashita, Tatsuki Koike, Haruhide Kimura, Gilles Tamagnan, Kouta Matsumiya, Jumpei Aida, Olivier Barret, Yasushi Hattori, Paul McQuade, Satoru Matsuda, Christine M Sandiego, Alexandra Gouasmat, Vincent M. Carroll
Publikováno v:
Journal of Medicinal Chemistry. 64:12680-12690
Histone methylation is associated with the pathophysiology of neurodevelopmental disorders. Lysine-specific demethylase 1 (LSD1) catalyzes histone demethylation in a flavin adenine dinucleotide (FAD)-dependent manner. Thus, inhibiting LSD1 enzyme act
Autor:
David Alagille, Satoru Matsuda, Rina Baba, Gilles Tamagnan, Thomas J. Morley, Yasushi Hattori, Tatsuki Koike, Caroline Papin, Cristian Constantinescu, Alexandra Gouasmat, Vincent M. Carroll, Shinji Iwasaki, Kouta Matsumiya
Publikováno v:
Journal of Medicinal Chemistry. 64:3780-3793
Dysregulation of histone H3 lysine 4 (H3K4) methylation is implicated in the pathogenesis of neurodevelopmental disorders. Lysine-specific demethylase 1 (LSD1) determines the methylation status of H3K4 through flavin adenine dinucleotide (FAD)-mediat
Autor:
Xianhong Xiang, Cedric Tresse, Thomas J. Morley, Vijay Gottmukkala, Zhengxin Cai, Tyler Teceno, Shil Patel, Olivier Barret, Stephen Krause, Alexandra Gouasmat, Jan Passchier, Songye Li, Vincent M. Carroll, Yiyun Huang, Ashley Knight, Wenjie Zhang
Publikováno v:
Molecular Imaging and Biology. 22:832-841
Current synaptic vesicle 2A (SV2A) positron emission tomography (PET) imaging agents include the nanomolar affinity probes [11C]UCB-J and [18F]UCB-H derived from the anti-epileptic drug levitaracetam (Keppra®). An industry-utilized “de-risking”
Autor:
Satoru, Matsuda, Yasushi, Hattori, Kouta, Matsumiya, Paul, McQuade, Tohru, Yamashita, Jumpei, Aida, Christine M, Sandiego, Alexandra, Gouasmat, Vincent M, Carroll, Olivier, Barret, Gilles, Tamagnan, Tatsuki, Koike, Haruhide, Kimura
Publikováno v:
Journal of medicinal chemistry. 64(17)
Histone methylation is associated with the pathophysiology of neurodevelopmental disorders. Lysine-specific demethylase 1 (LSD1) catalyzes histone demethylation in a flavin adenine dinucleotide (FAD)-dependent manner. Thus, inhibiting LSD1 enzyme act
Autor:
Guillaume Despras, Boris Vauzeilles, Alexandra Gouasmat, Dominique Urban, Géraldine San Jose, Jean-Marie Beau, Yann Bourdreux
Publikováno v:
Protecting Groups
Autor:
Isabella de Jong, Herman Gill, Simon-Peter Williams, Jan Marik, Ohad Ilovich, Jian Yin, Jihong Yang, Alexandra Gouasmat, Minh Michael Phan, Richard Seipert, Vincent M. Carroll, Xiangdan Wang, Annie Ogasawara
Publikováno v:
The AAPS Journal. 22
Immuno-PET is a molecular imaging technique utilizing positron emission tomography (PET) to measure the biodistribution of an antibody species labeled with a radioactive isotope. When applied as a clinical imaging technique, an immuno-PET imaging age
Autor:
Ming-Qiang Zheng, Vincent M. Carroll, Cedric Tresse, John Seibyl, Laetitia Mistico, Cristian Constantinescu, Olivier Barret, David Alagille, Alexandra Gouasmat, Christine M. Sandiego, Kenneth Marek, Gilles Tamagnan, Caroline Papin
Publikováno v:
Molecular Imaging and Biology. 21:509-518
Synaptic vesicle protein 2A (SV2A) serves as a biomarker of synaptic density and positron emission tomography (PET) imaging of SV2A could provide a tool to assess progression of neurodegenerative diseases. Two tracers have primarily been reported and
Publikováno v:
European Journal of Organic Chemistry. 2017:3355-3361
Regioselective differentiation of the hydroxy groups of mono- and oligosaccharide substrates is necessary to form building blocks that can be used for synthetic transformations. In this paper, we show that iron(III) chloride hexahydrate catalyses the
Autor:
Herman, Gill, Richard, Seipert, Vincent M, Carroll, Alexandra, Gouasmat, Jian, Yin, Annie, Ogasawara, Isabella, de Jong, Minh Michael, Phan, Xiangdan, Wang, Jihong, Yang, Ohad, Ilovich, Jan, Marik, Simon-Peter, Williams
Publikováno v:
The AAPS journal. 22(2)
Immuno-PET is a molecular imaging technique utilizing positron emission tomography (PET) to measure the biodistribution of an antibody species labeled with a radioactive isotope. When applied as a clinical imaging technique, an immuno-PET imaging age
Autor:
Jean-Marie Beau, Yann Bourdreux, Francois-Didier Boyer, Stephanie Norsikian, Dominique Urban, Gilles Doisneau, Boris Vauzeilles, Alexandra Gouasmat, Aurelie Lemetais, Aurelie Mathieu, et al. et al.
Publikováno v:
ChemInform. 45