Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Alexandra Gauthier"'
Autor:
Evrim Goksel, Elif Ugurel, Elie Nader, Camille Boisson, Ingrid Muniansi, Philippe Joly, Celine Renoux, Alexandra Gauthier, Philippe Connes, Ozlem Yalcin
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Sickle cell disease (SCD) is an inherited hemoglobinopathy characterized by chronic anemia, intravascular hemolysis, and the occurrence of vaso-occlusive crises due to the mechanical obstruction of the microcirculation by poorly deformable red blood
Externí odkaz:
https://doaj.org/article/696fcdb0ef6c44958115c59db77ec523
Autor:
Sofia Esperti, Elie Nader, Antoine Stier, Camille Boisson, Romain Carin, Muriel Marano, Mélanie Robert, Marie Martin, Françoise Horand, Agnes Cibiel, Céline Renoux, Robin Van Bruggen, Colin Blans, Yesim Dargaud, Philippe Joly, Alexandra Gauthier, Solène Poutrel, Marc Romana, Damien Roussel, Philippe Connes
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Abnormal retention of mitochondria in mature red blood cells (RBC) has been recently reported in sickle cell anemia (SCA) but their functionality and their role in the pathophysiology of SCA remain unknown. The presence of mitochondria within RBC was
Externí odkaz:
https://doaj.org/article/384030a7517d42a8b9b05613491174cd
Autor:
Claire Falguière, Slimane Allali, Bassem Khazem, Annie Kamdem, Cécile Arnaud, Marie Belloy, Corinne Guitton, Marie-Hélène Odièvre, Sophie Pertuisel, Cecile Dumesnil, Cécile Guillaumat, Nathalie Garrec, Alexandra Gauthier, Perrine Mahe, Valerie Soussan-Banini, Laure Le-Carrer, Etienne Merlin, Audrey David, Beatrice Pellegrino, Catherine Paillard, Jean-Francois Brasme, Marie Lagarde, France Pirenne, Corinne Pondarre
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Externí odkaz:
https://doaj.org/article/55f34e53da9c4d878fc44b17019665a0
Autor:
Sachi Sant, Etienne Gouraud, Camille Boisson, Elie Nader, Mounika Goparaju, Giovanna Cannas, Alexandra Gauthier, Philippe Joly, Céline Renoux, Salima Merazga, Christophe Hautier, Philippe Connes, Marianne Fenech
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3621 (2023)
Patients with sickle cell disease (SCD) have poorly deformable red blood cells (RBC) that may impede blood flow into microcirculation. Very few studies have been able to directly visualize microcirculation in humans with SCD. Sublingual video microsc
Externí odkaz:
https://doaj.org/article/645c1e626e8a4c8eb8ee5354054b1ff5
Autor:
Viviana Clavería, Philippe Connes, Luca Lanotte, Céline Renoux, Philippe Joly, Romain Fort, Alexandra Gauthier, Christian Wagner, Manouk Abkarian
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Red blood cells in sickle cell anemia (sRBC) are more heterogeneous in their physical properties than healthy red blood cells, spanning adhesiveness, rigidity, density, size, and shape. sRBC with increased adhesiveness to the vascular wall would trig
Externí odkaz:
https://doaj.org/article/3940873705f7411a8008eda9a73fe28b
Autor:
Olivier Hequet, Camille Boisson, Philippe Joly, Daniela Revesz, Kamila Kebaili, Alexandra Gauthier, Celine Renoux, Severine Creppy, Elie Nader, Jean François Nicolas, Frédéric Berard, Fabrice Cognasse, Marc Vocanson, Yves Bertrand, Philippe Connes
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Red blood cell exchanges are frequently used to treat and prevent cerebrovascular complications in patients with sickle cell anemia (SCA). However, the low weight of young children represents serious concerns for this procedure. The Spectra Optia dev
Externí odkaz:
https://doaj.org/article/a0f00bdfa4ae42e1842279d3e3db4551
Autor:
Delphine Hoegy, Nathalie Bleyzac, Alexandra Gauthier-Vasserot, Giovanna Cannas, Angélique Denis, Arnaud Hot, Yves Bertrand, Pauline Occelli, Sandrine Touzet, Claude Dussart, Audrey Janoly-Dumenil, DREPADO study group
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Thanks to advancements in medical care, a majority of patients with sickle cell disease (SCD) worldwide live beyond 18 years of age, and therefore, patients initially followed in paediatric departments are then transferred to adul
Externí odkaz:
https://doaj.org/article/23902f8b88044cd9a45806f2a72e32ae
Autor:
Emeric Stauffer, Solène Poutrel, Giovanna Cannas, Alexandra Gauthier, Romain Fort, Yves Bertrand, Céline Renoux, Philippe Joly, Camille Boisson, Arnaud Hot, Laure Peter-Derex, Vincent Pialoux, Thierry PetitJean, Philippe Connes
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Although obstructive sleep apnea (OSA) could act as a modulator of clinical severity in sickle cell disease (SCD), few studies focused on the associations between the two diseases.Research Question: The aims of this study were: (1) to exp
Externí odkaz:
https://doaj.org/article/15d1bceb911b439fb6c1d480d4dd6d54
Autor:
Elie Nader, Marc Romana, Nicolas Guillot, Romain Fort, Emeric Stauffer, Nathalie Lemonne, Yohann Garnier, Sarah Chambers Skinner, Maryse Etienne-Julan, Mélanie Robert, Alexandra Gauthier, Giovanna Cannas, Sophie Antoine-Jonville, Benoît Tressières, Marie-Dominique Hardy-Dessources, Yves Bertrand, Cyril Martin, Céline Renoux, Philippe Joly, Marijke Grau, Philippe Connes
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO are known to modulate eryptosis in healthy red blood cells (RBCs); however, their
Externí odkaz:
https://doaj.org/article/327d7cbdbea248aeb284d431ff770a87
Autor:
Camille Boisson, Elie Nader, Céline Renoux, Alexandra Gauthier, Solène Poutrel, Yves Bertrand, Emeric Stauffer, Emilie Virot, Arnaud Hot, Romain Fort, Giovanna Cannas, Philippe Joly, Philippe Connes
Publikováno v:
Cells, Vol 11, Iss 3, p 585 (2022)
Oxygen gradient ektacytometry (oxygenscan) measures the changes in red blood cell (RBC) deformability in normoxia and during deoxygenation. We investigated the changes in RBC deformability, measured by both oxygenscan and classical shear-stress-gradi
Externí odkaz:
https://doaj.org/article/c5d5b719306a40bdb625b62e45abaa78