Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexandra GÖKE"'
Publikováno v:
British Journal of Pharmacology. 139:495-500
(1) Bisphenol A diglycidyl ether (BADGE) is a peroxisome proliferator-activated receptor-gamma (PPAR-gamma) antagonist, which is able to induce apoptosis in tumor cells independently of PPAR-gamma in caspase-dependent and -independent manners. Additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c97365a1838e6bb5aad745e57f0ca2f
https://doi.org/10.1038/sj.bjp.0705275
https://doi.org/10.1038/sj.bjp.0705275
Autor:
Anja Knolle, Ruaidhrí J. Carmody, Alexandra Göke, Burkhard Göke, Rüdiger Göke, Youhai H. Chen, Harald Schmidt, Andreas Wilmen, Heidi Trusheim
Publikováno v:
Biochemical and Biophysical Research Communications. 297:78-82
To elucidate the molecular mechanisms of cell death, we have cloned a new gene, designated death-upregulated gene (DUG), from rat insulinoma cells. DUG is constitutively expressed at very low levels in normal cells but is dramatically upregulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f352185c7c79cb5d77271c2df695af2
https://doi.org/10.1016/s0006-291x(02)02129-0
https://doi.org/10.1016/s0006-291x(02)02129-0
Publikováno v:
Biochemical Journal. 362:573-578
Peroxisome proliferator-activated receptors (PPARs) are nuclear transcription factors which are involved in many biological processes, such as regulation of cell differentiation, lipid metabolism, inflammation and cell death. PPARs consist of three f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f87cbf1f102e2f572257fc48bd92b5
https://doi.org/10.1042/bj3620573
https://doi.org/10.1042/bj3620573
Publikováno v:
Digestion. 64:75-80
Background/Aims: We investigated the effect of the peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist pioglitazone on growth and TRAIL-induced apoptosis in carcinoid cells. Methods: Carcinoid cells were incubated without and with pioglit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc1f99b9a85b951f83ac208658d4de3
https://doi.org/10.1159/000048843
https://doi.org/10.1159/000048843
Autor:
Rüdiger Göke, Kaimei Song, Alexandra Göke, Cheryl Seidel, Yiguang Chen, Brendan Hilliard, Youhai H. Chen, Andreas Wilmen
Publikováno v:
The Journal of Experimental Medicine
The tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) induces apoptosis of tumor cells but not normal cells; its role in normal nontransformed tissues is unknown. We report here that chronic blockade of TRAIL in mice exacerbated autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11312a063d6f7cad2012ef4d2103994f
https://doi.org/10.1084/jem.191.7.1095
https://doi.org/10.1084/jem.191.7.1095
Publikováno v:
Cellular immunology. 201(2)
In 1995, tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) was identified based on its sequence homology to other TNF family members (1). Among members of the TNF family, TRAIL shares the highest sequence homology with Fas ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547995706f496b3bc70bddff5520a702
https://pubmed.ncbi.nlm.nih.gov/10831316
https://pubmed.ncbi.nlm.nih.gov/10831316
Autor:
Rudolf Arnold, Alexandra Göke, C. Gregel, Rüdiger Göke, Harald Schmidt, Brigitte Lankat-Buttgereit
Publikováno v:
Annals of the New York Academy of Sciences. 1014:220-221
PDCD4 is a new tumor suppressor gene. In the current study, we show that overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation. This is most likely caused by a PDCD4-induced downregulation of carbonic anhydrase type I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f35304b14d5f5b21c5da3228ab9f68
https://doi.org/10.1196/annals.1294.024
https://doi.org/10.1196/annals.1294.024