Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexandra F. Putka"'
Autor:
Frederick J. Arnold, Alexandra F. Putka, Urmimala Raychaudhuri, Solomon Hsu, Richard S. Bedlack, Craig L. Bennett, Albert R. La Spada
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5587 (2024)
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disorder. While there are five FDA-approved drugs for treating this disease, each has only modest benefits. To design new and more effective therapies for ALS, particularly for spora
Externí odkaz:
https://doaj.org/article/d20eaf2f4c424d2b8c67b0bff66a8ea7
Autor:
Kristen H. Schuster, Danielle M. DiFranco, Alexandra F. Putka, Juan P. Mato, Sabrina I. Jarrah, Nicholas R. Stec, Vikram O. Sundararajan, Hayley S. McLoughlin
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disease caused by a CAG repeat expansion in the ATXN3 gene. Though the ATXN3 protein is expressed ubiquitously throughout the CNS, regional pathology in SCA3 patients is observed within sele
Externí odkaz:
https://doaj.org/article/6737c8cc4b5e49f8befd2d154d84aac9
Publikováno v:
Cells, Vol 12, Iss 4, p 601 (2023)
Human studies, in combination with animal and cellular models, support glial cells as both major contributors to neurodegenerative diseases and promising therapeutic targets. Among glial cells, oligodendrocytes and Schwann cells are the myelinating g
Externí odkaz:
https://doaj.org/article/5f245f6cf9ad4cd9ae3dafd71e480c2c
Publikováno v:
Cells, Vol 11, Iss 16, p 2615 (2022)
Emerging evidence has implicated non-neuronal cells, particularly oligodendrocytes, in the pathophysiology of many neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disea
Externí odkaz:
https://doaj.org/article/122c89bea9924dfda1ce58cefe476693
Autor:
Kristen H. Schuster, Annie J. Zalon, Danielle M. DiFranco, Alexandra F. Putka, Nicholas Stec, Sabrina Jarrah, Arsal Naeem, Zaid Haque, Hongjiu Zhang, Yuanfang Guan, Hayley S. McLoughlin
Spinocerebellar ataxia type 3 (SCA3) is the most common dominantly inherited ataxia. Currently, no preventative or disease-modifying treatments exist for this progressive neurodegenerative disorder, although efforts using gene silencing approaches ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c572e0f051424895909d2b7bfe4c0af
https://doi.org/10.1101/2022.07.18.500473
https://doi.org/10.1101/2022.07.18.500473
