Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexandra E. Paharik"'
Autor:
Alexandra E. Paharik, Henry L. Schreiber, Caitlin N. Spaulding, Karen W. Dodson, Scott J. Hultgren
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-4 (2017)
Editorial summary Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial mic
Externí odkaz:
https://doaj.org/article/f84b021d73e44538a9cc72a810556195
Autor:
Alexandra E. Paharik, Wilmara Salgado-Pabon, David K. Meyerholz, Mark J. White, Patrick M. Schlievert, Alexander R. Horswill
Publikováno v:
mSphere, Vol 1, Iss 5 (2016)
ABSTRACT The Spl proteases are a group of six serine proteases that are encoded on the νSaβ pathogenicity island and are unique to Staphylococcus aureus. Despite their interesting biochemistry, their biological substrates and functions in virulence
Externí odkaz:
https://doaj.org/article/12e10c29758d4e8abac34b089f61f88d
Autor:
Colin J. Worby, Henry L. Schreiber, Timothy J. Straub, Lucas R. van Dijk, Ryan A. Bronson, Benjamin S. Olson, Jerome S. Pinkner, Chloe L. P. Obernuefemann, Vanessa L. Muñoz, Alexandra E. Paharik, Philippe N. Azimzadeh, Bruce J. Walker, Christopher A. Desjardins, Wen-Chi Chou, Karla Bergeron, Sinéad B. Chapman, Aleksandra Klim, Abigail L. Manson, Thomas J. Hannan, Thomas M. Hooton, Andrew L. Kau, H. Henry Lai, Karen W. Dodson, Scott J. Hultgren, Ashlee M. Earl
Publikováno v:
Nature Microbiology. 7:630-639
Recurrent urinary tract infections (rUTIs) are a major health burden worldwide, with history of infection being a significant risk factor. While the gut is a known reservoir for uropathogenic bacteria, the role of the microbiota in rUTI remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d5ca8ef67bcf11c4e13ee2d5ffd68f
https://doi.org/10.1038/s41564-022-01107-x
https://doi.org/10.1038/s41564-022-01107-x
Autor:
Alexandra E. Paharik, Karla Bergeron, Thomas J. Hannan, Timothy J. Straub, Ashlee M. Earl, Scott J. Hultgren, Wen-Chi Chou, Henry L. Schreiber, Andrew L. Kau, Christopher A. Desjardins, Abigail L. Manson, Ryan A. Bronson, Lucas R. van Dijk, Karen W. Dodson, Aleksandra Klim, Sinéad B. Chapman, Vanessa L. Muñoz, Chloe L. P. Obernuefemann, Jerome S. Pinkner, Colin J. Worby, Bruce J. Walker, H. Henry Lai, Benjamin Olson, Thomas M. Hooton
Recurrent urinary tract infections (rUTIs) are a major health burden worldwide, with history of infection being a significant risk factor. While the gut is a known reservoir for uropathogenic bacteria, the role of the microbiota in rUTI remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c2ec320be5191412a9b591cb5e5f7f
https://doi.org/10.1101/2021.11.15.21266268
https://doi.org/10.1101/2021.11.15.21266268
Autor:
Caitlin N. Spaulding, Karen W. Dodson, Alexandra E. Paharik, Scott J. Hultgren, Henry L. Schreiber
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-4 (2017)
Genome Medicine
Genome Medicine
Editorial summary Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00589cd7b7c7953f024dd35e041711af
http://link.springer.com/article/10.1186/s13073-017-0504-3
http://link.springer.com/article/10.1186/s13073-017-0504-3
Autor:
Tra My N. Hoang, Marta Kotasinska, Henning Büttner, Paul D. Fey, Holger Rohde, Anna Both, Paroma Roy, Alexandra E. Paharik, Alexander R. Horswill
Publikováno v:
Molecular Microbiology. 103:860-874
The otherwise harmless skin inhabitant Staphylococcus epidermidis is a major cause of healthcare-associated medical device infections. The species' selective pathogenic potential depends on its production of surface adherent biofilms. The Cell wall-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81cd424570198c6d568cd9fdbb43c19c
https://doi.org/10.1111/mmi.13594
https://doi.org/10.1111/mmi.13594
Publikováno v:
ACS Chemical Biology. 11:1982-1991
Staphylococcus epidermidis is frequently implicated in human infections associated with indwelling medical devices due to its ubiquity in the skin flora and formation of robust biofilms. The accessory gene regulator (agr) quorum sensing (QS) system p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5074bd54b306afc27c45339ad11218
https://doi.org/10.1021/acschembio.6b00120
https://doi.org/10.1021/acschembio.6b00120
Autor:
Sachinkumar B. Singh, Timothy D. Starner, Laynez W. Ackermann, Annie U. Shelton, Alexander R. Horswill, Megan R. Kiedrowski, Alexandra E. Paharik
Publikováno v:
Cellular Microbiology. 18:720-732
Staphylococcus aureus is a bacterial pathogen responsible for a wide range of diseases and is also a human commensal colonizing the upper respiratory tract. Strains belonging to the clonal complex group CC30 are associated with colonization, although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::112424cada7f6a27e61e4ca25a741efd
https://doi.org/10.1111/cmi.12543
https://doi.org/10.1111/cmi.12543
Autor:
G. Matt Longo, Paul D. Fey, Alexandra E. Paharik, Megan R. Kiedrowski, Keith M. Woods, Henning Büttner, Robert Boissy, Holger Rohde, Carolyn R. Schaeffer, Martin Christner, Alexander R. Horswill
Publikováno v:
Infection and Immunity. 83:214-226
Biofilm formation is the primary virulence factor of Staphylococcus epidermidis . S. epidermidis biofilms preferentially form on abiotic surfaces and may contain multiple matrix components, including proteins such as accumulation-associated protein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0200728d996555fad0d36da92df2f0c3
https://doi.org/10.1128/iai.02177-14
https://doi.org/10.1128/iai.02177-14