Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexandra E. Oxford"'
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2020 (2020)
Human clinical trials seek to ameliorate the disease states and symptomatic progression of illnesses that, as of yet, are largely untreatable according to clinical standards. Ideally, clinical trials test “disease-modifying drugs,” i.e., therapeu
Externí odkaz:
https://doaj.org/article/fa2b0c11b69a4d71b71066c134daf0ad
Publikováno v:
Pathogens, Vol 9, Iss 10, p 785 (2020)
Understanding of the clinical, histological and molecular features of the novel coronavirus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)) has remained elusive. Coronavirus disease 2019 (COVID-19) caused by this virus has unusual
Externí odkaz:
https://doaj.org/article/01d315ba20bc4d68bee17e5bdf57f556
Autor:
Alejandro Soto-Avellaneda, Alexandra E Oxford, Fabio Halla, Peyton Vasquez, Emily Oe, Anton D Pugel, Alyssa M Schoenfeld, Matthew C Tillman, André Cuevas, Eric A Ortlund, Brad E Morrison
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0300168 (2024)
The motor features of Parkinson's disease result from loss of dopaminergic neurons in the substantia nigra with autophagy dysfunction being closely linked to this disease. While a large body of work focusing on protein effectors of autophagy has been
Externí odkaz:
https://doaj.org/article/de46c7140f8a403d93f3dd9bc684fa6c
Autor:
Alejandro Soto-Avellaneda, Anton D. Pugel, Jocelyn R. Holmes, Alyssa M. Schoenfeld, Sara Z. Alsaifi, Gyandarshika Koirala, Alexandra E. Oxford, Brad Morrison
A growing number of studies have reported the transduction of a myriad of parenchymal cell types following an intravenous recombinant adeno-associated virus (rAAV) injection. This finding has significant implications for potential routes of minimally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f93f57ebe6c716495444b0aa3f141e
Autor:
Jacob P. Valarde, Abby R. Webb, Abir A Rahman, Brandon Wagner, Paige E. Urquhart, Alejandro Soto-Avellaneda, Iva Stojkovska, Brad E. Morrison, Nathan Lai, Joshua E Albright, Isabella Amado, Karin M Danzer, Hyun Yong Jin, Peyton B. Vasquez, Veselin Grozdanov, Connor J. Brown, Alexandra E. Oxford, Emily Oe, Nicholas Lehning, Xinzhu Pu
Publikováno v:
Neuroscience
The motor features of Parkinson’s disease (PD) result from the loss of dopaminergic (DA) neurons in the substantia nigra with autophagy dysfunction being closely linked to this disease. A PD-causing familial mutation in VPS35 (D620N) has been repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca38f06e6a4b425144498630f097cf2
https://europepmc.org/articles/PMC7390708/
https://europepmc.org/articles/PMC7390708/
Autor:
Ryan Day, Alexandra E. Oxford, Raquel J. Brown, Eric J. Hayden, Jacob M Mack, Brad E. Morrison, Noail F Isho, Troy T. Rohn, Tanner B Pollock
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Despite the fact that harboring the apolipoprotein E4 (APOE4) allele represents the single greatest risk factor for late-onset Alzheimer’s disease (AD), the exact mechanism by which apoE4 contributes to disease progression remains unknown. Recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c24ee4e4044c6f91fcb3789ec23bc1
https://pubmed.ncbi.nlm.nih.gov/31198491
https://pubmed.ncbi.nlm.nih.gov/31198491
Publikováno v:
Pathogens, Vol 9, Iss 785, p 785 (2020)
Pathogens
Pathogens
Understanding of the clinical, histological and molecular features of the novel coronavirus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)) has remained elusive. Coronavirus disease 2019 (COVID-19) caused by this virus has unusual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf25985336f09062ce2f7b1af8469693
https://doi.org/10.3390/pathogens9100785
https://doi.org/10.3390/pathogens9100785
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 3, p 665 (2017)
International Journal of Molecular Sciences, Vol 18, Iss 3, p 665 (2017)
Chondrocytes of the growth plate undergo apoptosis during the process of endochondral ossification, as well as during the progression of osteoarthritis. Although the regulation of this process is not completely understood, alterations in the precisel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb5777b71317ad4f6d37a8672bc23b6
https://pubmed.ncbi.nlm.nih.gov/28335520
https://pubmed.ncbi.nlm.nih.gov/28335520
Stuve-Wiedemann syndrome (STWS; OMIM #610559) is a rare disease that results in dysfunction of the autonomic nervous system, which controls involuntary processes such as breathing rate and body temperature. In infants, this can result in respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94968922d8b1a7c75c2fa0436c72a4c
https://europepmc.org/articles/PMC5207777/
https://europepmc.org/articles/PMC5207777/