Transcriptional regulation of two stage-specifically expressed genes in the protozoan parasite Toxoplasma gondii

Autor: Edwige Madec, Stanislas Tomavo, Edwige Meurice, Alexandra Coppin, Najoua Dendouga, Gabrielle Oria, Marlène Mortuaire, MK Kibe

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2005, 33(5), pp.1722-36
Nucleic Acids Research, 2005, 33(5), pp.1722-36

The protozoan parasite Toxoplasma gondii differentially expresses two distinct enolase isoenzymes known as ENO1 and ENO2, respectively. To understand differential gene expression during tachyzoite to bradyzoite conversion, we have characterized the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec18b5e4cc03d05257c1cefdd820db3
http://europepmc.org/articles/PMC1903550

Functional Analysis of Toxoplasma gondii Protease Inhibitor 1

Autor: Meredith Morris, Alexandra Coppin, Vern B. Carruthers, Stanislas Tomavo

Publikováno v: Journal of Biological Chemistry. 277:45259-45266

We have characterized a Kazal family serine protease inhibitor, Toxoplasma gondii protease inhibitor 1 (TgPI-1), in the obligate intracellular parasite Toxoplasma gondii. TgPI-1 contains four inhibitor domains predicted to inhibit trypsin, chymotryps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80dc7d665d4ad74570c79399cd0ccd13
https://doi.org/10.1074/jbc.m205517200

Synthesis and in vitro activities of ferrocenic aminohydroxynaphthoquinones against Toxoplasma gondii and Plasmodium falciparum

Autor: Alexandra Coppin, Apiwat Baramee, Jacques Brocard, Marlène Mortuaire, Lydie Pelinski, Stanislas Tomavo

Publikováno v: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, 2006, 14(5), pp.1294-302
Bioorganic and Medicinal Chemistry, Elsevier, 2006, 14(5), pp.1294-302

Fourteen ferrocenyl aminohydroxynaphthoquinones, analogues of atovaquone, were synthesized from the hydroxynaphthoquinone core. These novel atovaquone derivatives were tested for their in vitro activity against two apicomplexan parasites of medical i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d14813e1ecd3b93126f25968fc0266
https://hal.science/hal-00086276

Evolution of plant-like crystalline storage polysaccharide in the protozoan parasite Toxoplasma gondii argues for a red alga ancestry

Autor: Steven G. Ball, David Dauvillée, Marie-Odile Soyer-Gobillard, Alain Buléon, Stanislas Tomavo, Alexandra Coppin, Luc Liénard, Yann Guérardel, Jean-Stéphane Varré

Publikováno v: Journal of Molecular Evolution
Journal of Molecular Evolution, Springer Verlag, 2005, 60 (2), pp.257-267. ⟨10.1007/s00239-004-0185-6⟩
Journal of Molecular Evolution, Springer Verlag, 2005, 60, pp.257-267
Journal of Molecular Evolution, 2005, 60, pp.257-267
Journal of Molecular Evolution, 2005, 60 (2), pp.257-267. ⟨10.1007/s00239-004-0185-6⟩

International audience; Single-celled apicomplexan parasites are known to cause major diseases in humans and animals including malaria, toxoplasmosis, and coccidiosis. The presence of apicoplasts with the remnant of a plastid-like DNA argues that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b35cdc19ad4b6947199ebf44babafb
https://hal.inrae.fr/hal-02680299

Species-specificity of amphibia carbohydrate chains: the Bufo viridis case study

Autor: Emmanuel Maes, Gérard Strecker, Alexandra Coppin

Publikováno v: Carbohydrate research. 337(2)

The jelly coat surrounding the eggs of amphibia is composed of oviducal mucins and plays an important role in the fertilization process. From a structural and chemical point of view, these jellies are very different from one species to another. Bufo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398118bf5d16303e8debf7fa3d075e25
https://pubmed.ncbi.nlm.nih.gov/11814443