Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Alexandra Chloé Villani"'
Autor:
Emma Hajaj, Galit Eisenberg, Shiri Klein, Shoshana Frankenburg, Sharon Merims, Inna Ben David, Thomas Eisenhaure, Sarah E Henrickson, Alexandra Chloé Villani, Nir Hacohen, Nathalie Abudi, Rinat Abramovich, Jonathan E Cohen, Tamar Peretz, Andre Veillette, Michal Lotem
Publikováno v:
eLife, Vol 9 (2020)
SLAMF6 is a homotypic receptor of the Ig-superfamily whose exact role in immune modulation has remained elusive. Its constitutive expression on resting and activated T cells precludes it from being a bona fide exhaustion marker. By breeding Pmel-1 mi
Externí odkaz:
https://doaj.org/article/e3efe8d8e0754d8bbbe2714fbaaca6ec
Autor:
Felix Fischer, David S. Fischer, Roman Mukhin, Andrey Isaev, Evan Biederstedt, Alexandra-Chloé Villani, Fabian J. Theis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Identifying cellular identities is a key use case in single-cell transcriptomics. While machine learning has been leveraged to automate cell annotation predictions for some time, there has been little progress in scaling neural networks to l
Externí odkaz:
https://doaj.org/article/238bbc0e49e9451a9362de533c6f954c
Autor:
Dong Sun Oh, Eunha Kim, Rachelly Normand, Guangqing Lu, Lydia L. Shook, Amanda Lyall, Olyvia Jasset, Stepan Demidkin, Emily Gilbert, Joon Kim, Babatunde Akinwunmi, Jessica Tantivit, Alice Tirard, Benjamin Y. Arnold, Kamil Slowikowski, Marcia B. Goldberg, Michael R. Filbin, Nir Hacohen, Long H. Nguyen, Andrew T. Chan, Xu G. Yu, Jonathan Z. Li, Lael Yonker, Alessio Fasano, Roy H. Perlis, Ofer Pasternak, Kathryn J. Gray, Gloria B. Choi, David A. Drew, Pritha Sen, Alexandra-Chloé Villani, Andrea G. Edlow, Jun R. Huh
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114933- (2024)
Summary: Pregnancy is a risk factor for increased severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory infections, but the mechanisms underlying this risk are poorly understood. To gain insight into the role
Externí odkaz:
https://doaj.org/article/19213902db5944c8b54efbe17b095882
Autor:
Anna L.K. Gonye, Thomas J. LaSalle, Samuel S. Freeman, Miguel Reyes, Nir Hacohen, Alexandra-Chloé Villani, Moshe Sade-Feldman
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102125- (2023)
Summary: Although neutrophils are the most abundant leukocyte in healthy individuals and impact outcomes of diseases ranging from sepsis to cancer, they remain understudied due to technical constraints of isolation, preservation, and sequencing. We p
Externí odkaz:
https://doaj.org/article/9f70286ed7c742c8aa1618af8f718569
Autor:
Elizabeth H. Byrne, Mara Farcasanu, Seth M. Bloom, Nondumiso Xulu, Jiawu Xu, Barry L. Hykes, Nomfuneko A. Mafunda, Matthew R. Hayward, Mary Dong, Krista L. Dong, Thandeka Gumbi, Fransisca Xolisile Ceasar, Nasreen Ismail, Thumbi Ndung’u, Christina Gosmann, Musie S. Ghebremichael, Scott A. Handley, Caroline M. Mitchell, Alexandra-Chloé Villani, Douglas S. Kwon
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The microbiome of the female genital tract (FGT) is closely linked to reproductive health outcomes. Diverse, anaerobe-dominated communities with low Lactobacillus abundance are associated with a number of adverse reproductive outcomes, such as preter
Externí odkaz:
https://doaj.org/article/86849ac40fd74dae97d282ac9d69d495
Autor:
Michael R. Filbin, Arnav Mehta, Alexis M. Schneider, Kyle R. Kays, Jamey R. Guess, Matteo Gentili, Bánk G. Fenyves, Nicole C. Charland, Anna L.K. Gonye, Irena Gushterova, Hargun K. Khanna, Thomas J. LaSalle, Kendall M. Lavin-Parsons, Brendan M. Lilley, Carl L. Lodenstein, Kasidet Manakongtreecheep, Justin D. Margolin, Brenna N. McKaig, Maricarmen Rojas-Lopez, Brian C. Russo, Nihaarika Sharma, Jessica Tantivit, Molly F. Thomas, Robert E. Gerszten, Graham S. Heimberg, Paul J. Hoover, David J. Lieb, Brian Lin, Debby Ngo, Karin Pelka, Miguel Reyes, Christopher S. Smillie, Avinash Waghray, Thomas E. Wood, Amanda S. Zajac, Lori L. Jennings, Ida Grundberg, Roby P. Bhattacharyya, Blair Alden Parry, Alexandra-Chloé Villani, Moshe Sade-Feldman, Nir Hacohen, Marcia B. Goldberg
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100287- (2021)
Summary: Mechanisms underlying severe coronavirus disease 2019 (COVID-19) disease remain poorly understood. We analyze several thousand plasma proteins longitudinally in 306 COVID-19 patients and 78 symptomatic controls, uncovering immune and non-imm
Externí odkaz:
https://doaj.org/article/c08db236b856403b84bbe1685b762818
Autor:
Jehan Alladina, Neal P. Smith, Tristan Kooistra, Kamil Slowikowski, Isabela J. Kernin, Jacques Deguine, Henry L. Keen, Kasidet Manakongtreecheep, Jessica Tantivit, Rod A. Rahimi, Susan L. Sheng, Nhan D. Nguyen, Alexis M. Haring, Francesca L. Giacona, Lida P. Hariri, Ramnik J. Xavier, Andrew D. Luster, Alexandra-Chloé Villani, Josalyn L. Cho, Benjamin D. Medoff
Publikováno v:
Science Immunology. 8
Asthma is a chronic disease most commonly associated with allergy and type 2 inflammation. However, the mechanisms that link airway inflammation to the structural changes that define asthma are incompletely understood. Using a human model of allergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac21e1ceafad0c752193c03305d44e3
https://doi.org/10.1126/sciimmunol.abq6352
https://doi.org/10.1126/sciimmunol.abq6352
Autor:
Rebecca A. Ward, George R. Thompson, Alexandra-Chloé Villani, Bo Li, Michael K. Mansour, Marcel Wuethrich, Jenny M. Tam, Bruce S. Klein, Jatin M. Vyas
Publikováno v:
Journal of Fungi, Vol 7, Iss 5, p 377 (2021)
Coccidioidomycosis, otherwise known as Valley Fever, is caused by the dimorphic fungi Coccidioides immitis and C. posadasii. While most clinical cases present with self-limiting pulmonary infection, dissemination of Coccidioides spp. results in prolo
Externí odkaz:
https://doaj.org/article/261d681f7cf84125916fca4d51db38db
Autor:
Maria S. Asdourian, Tracey S. Otto, Ted V. Jacoby, Nishi Shah, Leah L. Thompson, Steven M. Blum, Kerry L. Reynolds, Yevgeniy R. Semenov, Donald P. Lawrence, Ryan J. Sullivan, Genevieve M. Boland, Alexandra-Chloé Villani, Steven T. Chen
Publikováno v:
Journal of the American Academy of Dermatology. 87:1147-1149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d00d60d62f04224738b1a989349991e
https://doi.org/10.1016/j.jaad.2022.02.024
https://doi.org/10.1016/j.jaad.2022.02.024
Autor:
Daniel E. Leisman, Arnav Mehta, B. Taylor Thompson, Nicole C. Charland, Anna L. K. Gonye, Irena Gushterova, Kyle R. Kays, Hargun K. Khanna, Thomas J. LaSalle, Kendall M. Lavin-Parsons, Brendan M. Lilley, Carl L. Lodenstein, Kasidet Manakongtreecheep, Justin D. Margolin, Brenna N. McKaig, Maricarmen Rojas-Lopez, Brian C. Russo, Nihaarika Sharma, Jessica Tantivit, Molly F. Thomas, Blair Alden Parry, Alexandra-Chloé Villani, Moshe Sade-Feldman, Nir Hacohen, Michael R. Filbin, Marcia B. Goldberg
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 205:507-519
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9dbc201c2fb4719c77af179901bc4a
https://doi.org/10.1164/rccm.202106-1514oc
https://doi.org/10.1164/rccm.202106-1514oc