Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexandra C. Turmon"'
Autor:
Tianyang Yan, Ashley R. Julio, Miranda Villanueva, Anthony E. Jones, Andréa B. Ball, Lisa M. Boatner, Alexandra C. Turmon, Stephanie L. Yen, Heta S. Desai, Ajit S. Divakaruni, Keriann M. Backus
Publikováno v:
bioRxiv
Proteinaceous cysteines function as essential sensors of cellular redox state. Consequently, defining the cysteine redoxome is a key challenge for functional proteomic studies. While proteome-wide inventories of cysteine oxidation state are readily a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cbb4e1c414583c633afd453ab7ccff
https://europepmc.org/articles/PMC9882296/
https://europepmc.org/articles/PMC9882296/
Autor:
Alexandra C Turmon, Matthew R. Naylor, R. Scott Lokey, Okimasa Okada, Hao-Yuan Wang, Walter M. Bray, Joshua Schwochert, Quinn Edmondson, Satoshi Ono, Jack Taunton, Victoria G. Klein, Justin H Faris
Publikováno v:
ACS Chem Biol
Cordyheptapeptide A is a lipophilic cyclic peptide from the prized Cordyceps fungal genus that shows potent cytotoxicity in multiple cancer cell lines. To better understand the bioactivity and physicochemical properties of cordyheptapeptide A with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ef22094d2527c9d53b0e48af95ef1d
https://doi.org/10.1021/acschembio.1c00094
https://doi.org/10.1021/acschembio.1c00094
Drug‐Like Properties in Macrocycles above MW 1000: Backbone Rigidity versus Side‐Chain Lipophilicity
Autor:
R. Scott Lokey, Victoria G. Klein, Daigo Asano, Quinn Edmondson, Cameron R. Pye, Akihiro Furukawa, Joshua Schwochert, Satoshi Ono, Okimasa Okada, Alexandra C Turmon
Publikováno v:
Angew Chem Int Ed Engl
Large, macrocyclic peptides can achieve surprisingly high membrane permeability, although the properties that govern permeability in this chemical space are only beginning to come into focus. We generated two libraries of cyclic decapeptides with sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1093734f1141e2862b09aace99f0bac8
https://doi.org/10.1002/anie.202004550
https://doi.org/10.1002/anie.202004550