Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Alexandra C. Racanelli"'
Autor:
Manyu Zhao, Liqun Wang, Mengzhu Wang, Shijie Zhou, Ying Lu, Huijie Cui, Alexandra C. Racanelli, Ling Zhang, Tinghong Ye, Bisen Ding, Ben Zhang, Jinliang Yang, Yuqin Yao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-21 (2022)
Abstract Fibrosis is characterized by the excessive extracellular matrix deposition due to dysregulated wound and connective tissue repair response. Multiple organs can develop fibrosis, including the liver, kidney, heart, and lung. Fibrosis such as
Externí odkaz:
https://doaj.org/article/8f258342cf4047a987ea70b05d80f6a6
Autor:
Barbara D. Summers, Kihwan Kim, Cristina C. Clement, Zohaib Khan, Sangeetha Thangaswamy, Jacob McCright, Katharina Maisel, Sofia Zamora, Stephanie Quintero, Alexandra C. Racanelli, David Redmond, Jeanine D’Armiento, Jisheng Yang, Amy Kuang, Laurel Monticelli, Mark L. Kahn, Augustine M. K. Choi, Laura Santambrogio, Hasina Outtz Reed
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The lymphatic vasculature is critical for lung function, but defects in lymphatic function in the pathogenesis of lung disease is understudied. In mice, lymphatic dysfunction alone is sufficient to cause lung injury that resembles human emph
Externí odkaz:
https://doaj.org/article/65625e4b867f4e81924ccad4d01752a0
Autor:
Mustafa Buyukozkan, Sergio Alvarez-Mulett, Alexandra C. Racanelli, Frank Schmidt, Richa Batra, Katherine L. Hoffman, Hina Sarwath, Rudolf Engelke, Luis Gomez-Escobar, Will Simmons, Elisa Benedetti, Kelsey Chetnik, Guoan Zhang, Edward Schenck, Karsten Suhre, Justin J. Choi, Zhen Zhao, Sabrina Racine-Brzostek, He S. Yang, Mary E. Choi, Augustine M.K. Choi, Soo Jung Cho, Jan Krumsiek
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104612- (2022)
Summary: The coronavirus disease-19 (COVID-19) pandemic has ravaged global healthcare with previously unseen levels of morbidity and mortality. In this study, we performed large-scale integrative multi-omics analyses of serum obtained from COVID-19 p
Externí odkaz:
https://doaj.org/article/a62f77fb3df5497ebf2ec8150d80ce78
Autor:
Chang Su, PhD, Katherine L. Hoffman, MS, Zhenxing Xu, PhD, Elizabeth Sanchez, MD, Ilias I. Siempos, MD, Dsc, John S. Harrington, MD, Alexandra C. Racanelli, MD, PhD, Maria Plataki, MD, PhD, Fei Wang, PhD, Edward J. Schenck, MD, MS
Publikováno v:
Critical Care Explorations, Vol 3, Iss 12, p e0589 (2021)
OBJECTIVES:. This report aims to characterize the kinetics of serum albumin in critically ill patients with coronavirus disease 2019 compared with critically ill patients with sepsis-induced acute respiratory distress syndrome. DESIGN:. Retrospective
Externí odkaz:
https://doaj.org/article/eb20a3dcb11046ef8e5660f1048d18fb
Publikováno v:
American Journal of Respiratory and Critical Care Medicine.
Autor:
David R. Price, Elisa Benedetti, Katherine L. Hoffman, Luis Gomez-Escobar, Sergio Alvarez-Mulett, Allyson Capili, Hina Sarwath, Christopher N. Parkhurst, Elyse Lafond, Karissa Weidman, Arjun Ravishankar, Jin Gyu Cheong, Richa Batra, Mustafa Büyüközkan, Kelsey Chetnik, Imaani Easthausen, Edward J. Schenck, Alexandra C. Racanelli, Hasina Outtz Reed, Jeffrey Laurence, Steven Z. Josefowicz, Lindsay Lief, Mary E. Choi, Frank Schmidt, Alain C. Borczuk, Augustine M.K. Choi, Jan Krumsiek, Shahin Rafii
Publikováno v:
The American Journal of Pathology. 192:1001-1015
Vascular injury is a well-established, disease-modifying factor in acute respiratory distress syndrome (ARDS) pathogenesis. Recently, coronavirus disease 2019 (COVID-19)-induced injury to the vascular compartment has been linked to complement activat
Autor:
Mark L. Kahn, Barbara D. Summers, Jacob McCright, Katharina Maisel, Zohaib Khan, Laurel Monticelli, Sofia Zamora, Sangeetha Thangaswamy, Augustine M.K. Choi, Jisheng Yang, Cristina C. Clement, Kihwan Kim, Laura Santambrogio, Hasina Outtz Reed, Stephanie Quintero, Jeanine D'Armiento, Alexandra C. Racanelli
The lymphatic vasculature is critical for lung function, but defects in lymphatic function in the pathogenesis of lung disease is understudied. In mice, lymphatic dysfunction alone is sufficient to cause lung injury that resembles human emphysema. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf01c49fa4aa5209824f12cd2e9a173
https://doi.org/10.21203/rs.3.rs-1024379/v1
https://doi.org/10.21203/rs.3.rs-1024379/v1
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Autor:
Mustafa Buyukozkan, Sergio Alvarez-Mulett, Alexandra C. Racanelli, Frank Schmidt, Richa Batra, Katherine L. Hoffman, Hina Sarwath, Rudolf Engelke, Luis Gomez-Escobar, Will Simmons, Elisa Benedetti, Kelsey Chetnik, Guoan Zhang, Edward Schenck, Karsten Suhre, Justin J. Choi, Zhen Zhao, Sabrina Racine-Brzostek, He S. Yang, Mary E. Choi, Augustine M.K. Choi, Soo Jung Cho, Jan Krumsiek
Publikováno v:
iScience. 25(7)
The novel coronavirus disease-19 (COVID-19) pandemic caused by SARS-CoV-2 has ravaged global healthcare with previously unseen levels of morbidity and mortality. To date, methods to predict the clinical course, which ranges from the asymptomatic carr
Autor:
Elisa Benedetti, Hina Sarwath, Kelsey Chetnik, Steven Z. Josefowicz, Mustafa Buyukozkan, Sergio Alvarez-Mulett, Jan Krumsiek, Augustine M.K. Choi, Jin Gyu Cheong, Shahin Rafii, Imaani Easthausen, Hasina Outtz Reed, Alain C. Borczuk, Frank Schmidt, Jeffrey Laurence, Luis Gomez-Escobar, Elyse LaFond, Katherine Hoffman, Christopher N. Parkhurst, Karissa Weidman, Lindsay Lief, Alexandra C. Racanelli, David R. Price, Arjun Ravishankar, Edward J. Schenck, Allyson Capili, Mary E. Choi, Richa Batra
Vascular injury is a menacing element of acute respiratory distress syndrome (ARDS) pathogenesis. To better understand the role of vascular injury in COVID-19 ARDS, we used lung autopsy immunohistochemistry and blood proteomics from COVID-19 subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df3897bed3ca39428e01ddc7597431f9
https://doi.org/10.1101/2021.05.20.21257542
https://doi.org/10.1101/2021.05.20.21257542