Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexandra C Brown"'
Autor:
Jemma R Mayall, Jay C Horvat, Niamh E Mangan, Anne Chevalier, Huw McCarthy, Daniel Hampsey, Chantal Donovan, Alexandra C Brown, Antony Y Matthews, Nicole A de Weerd, Eveline D de Geus, Malcolm R Starkey, Richard Y Kim, Katie Daly, Bridie J Goggins, Simon Keely, Steven Maltby, Rennay Baldwin, Paul S Foster, Michael J Boyle, Pradeep S Tanwar, Nicholas D Huntington, Paul J Hertzog, Philip M Hansbro
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 2, Pp 267-293 (2024)
Abstract The uterus is a unique mucosal site where immune responses are balanced to be permissive of a fetus, yet protective against infections. Regulation of natural killer (NK) cell responses in the uterus during infection is critical, yet no studi
Externí odkaz:
https://doaj.org/article/27c077dad3a5489b8adb434699dbf324
Autor:
Alexandra C. Brown, Daniel L. M. Suess
Publikováno v:
Journal of the American Chemical Society. 145:2075-2080
Autor:
Celine Vidaillac, Valerie Fei Lee Yong, Marie-Stephanie Aschtgen, Jing Qu, Shuowei Yang, Guangfu Xu, Zi Jing Seng, Alexandra C. Brown, Md Khadem Ali, Tavleen K. Jaggi, Jagadish Sankaran, Yong Hwee Foo, Francesco Righetti, Anu Maashaa Nedumaran, Micheál Mac Aogáin, Dan Roizman, Jean-Alexandre Richard, Thomas R. Rogers, Masanori Toyofuku, Dahai Luo, Edmund Loh, Thorsten Wohland, Bertrand Czarny, Jay C. Horvat, Philip M. Hansbro, Liang Yang, Liang Li, Staffan Normark, Birgitta Henriques-Normark, Sanjay H. Chotirmall
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
Externí odkaz:
https://doaj.org/article/c28fd07a0c564aec9c94a5818f69e570
Autor:
Celine Vidaillac, Valerie Fei Lee Yong, Marie-Stephanie Aschtgen, Jing Qu, Shuowei Yang, Guangfu Xu, Zi Jing Seng, Alexandra C. Brown, Md Khadem Ali, Tavleen K. Jaggi, Jagadish Sankaran, Yong Hwee Foo, Francesco Righetti, Anu Maashaa Nedumaran, Micheál Mac Aogáin, Dan Roizman, Jean-Alexandre Richard, Thomas R. Rogers, Masanori Toyofuku, Dahai Luo, Edmund Loh, Thorsten Wohland, Bertrand Czarny, Jay C. Horvat, Philip M. Hansbro, Liang Yang, Liang Li, Staffan Normark, Birgitta Henriques-Normark, Sanjay H. Chotirmall
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Estrogen, a major female sex steroid hormone, has been shown to promote the selection of mucoid Pseudomonas aeruginosa in the airways of patients with chronic respiratory diseases, including cystic fibrosis. This results in long-term persist
Externí odkaz:
https://doaj.org/article/a70f533655e045bc87d30e38bc6cedeb
Autor:
Henry M. Gomez, Amber L. Pillar, Alexandra C. Brown, Richard Y. Kim, Md Khadem Ali, Ama-Tawiah Essilfie, Rebecca L. Vanders, David M. Frazer, Gregory J. Anderson, Philip M. Hansbro, Adam M. Collison, Megan E. Jensen, Vanessa E. Murphy, Daniel M. Johnstone, David Reid, Elizabeth A. Milward, Chantal Donovan, Jay C. Horvat
Publikováno v:
Nutrients, Vol 13, Iss 12, p 4461 (2021)
Maternal iron deficiency occurs in 40–50% of all pregnancies and is associated with an increased risk of respiratory disease and asthma in children. We used murine models to examine the effects of lower iron status during pregnancy on lung function
Externí odkaz:
https://doaj.org/article/86616bff9e1545e4b15983abc69196c7
Autor:
Rebecca J. Marshall, Pornthida Armart, Katina D. Hulme, Keng Yih Chew, Alexandra C. Brown, Philip M. Hansbro, Conor J. Bloxham, Melanie Flint, Katharina Ronacher, Helle Bielefeldt-Ohmann, Linda A. Gallo, Kirsty R. Short
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT People with diabetes are two times more likely to die from influenza than people with no underlying medical condition. The mechanisms underlying this susceptibility are poorly understood. In healthy individuals, small and short-lived postpra
Externí odkaz:
https://doaj.org/article/e7526e11425e4113be3ebc0f2d499ad6
Publikováno v:
J Am Chem Soc
Synthetic [Fe(4)S(4)] clusters with Fe–R groups (R = alkyl/benzyl) are shown to release organic radicals on an [Fe(4)S(4)](3+)–R/[Fe(4)S(4)](2+) redox couple, the same that has been proposed for a radical-generating intermediate in the superfamil
Autor:
Alexandra C. Brown, Daniel L. M. Suess
Publikováno v:
Inorg Chem
Reported herein are alkyne and alkene adducts of synthetic [Fe(4)S(4)](+) clusters that model intermediates and inhibitor-bound states in enzymes involved in isoprenoid biosynthesis. Treatment of the N-heterocyclic carbene-ligated cluster [(IMes)(3)F
Publikováno v:
Nature Synthesis.
Autor:
Shu Ren, Philip M. Hansbro, Wichat Srikusalanukul, Jay C. Horvat, Tegan Hunter, Alexandra C. Brown, Roseanne Peel, Jack Faulkner, Tiffany-Jane Evans, Shu Chuen Li, David Newby, Alexis Hure, Walter P. Abhayaratna, Sotirios Tsimikas, Ayelet Gonen, Joseph L. Witztum, John Attia, Walter Abhayaratna, Catherine D'Este, Andrew Tonkin, Ingrid Hopper, Amanda Thrift, Christopher Levi, Jonathan Sturm, David Durrheim, Joseph Hung, Tom Briffa, Derek Chew, Phil Anderson, Lynelle Moon, Mark McEvoy
Publikováno v:
Atherosclerosis. 346:68-74
Observational studies have demonstrated that the pneumococcal polysaccharide vaccine (PPV) is associated with reduced risk of cardiovascular events. This may be mediated through IgM antibodies to OxLDL, which have previously been associated with card