Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexandra B. Sassi"'
Autor:
Alexander M Cole, Dorothy L Patton, Lisa C Rohan, Amy L Cole, Yvonne Cosgrove-Sweeney, Nicole A Rogers, Deena Ratner, Alexandra B Sassi, Carol Lackman-Smith, Patrick Tarwater, Bharat Ramratnam, Piotr Ruchala, Robert I Lehrer, Alan J Waring, Phalguni Gupta
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15111 (2010)
RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell c
Externí odkaz:
https://doaj.org/article/e2d818de95fa4083945b9aaca638183a
Publikováno v:
Journal of Pharmaceutical Sciences. 93:2009-2016
The increased incidence of human immunodeficiency virus infection in women has identified an urgent need to develop a female-controlled method to prevent acquisition of human immunodeficiency virus and other sexually transmitted diseases. Women would
Autor:
Lisa C. Rohan, Dorothy L. Patton, Charles E. Isaacs, Lin Wang, Alexandra B. Sassi, Bernard J. Moncla, Phalguni Gupta
Publikováno v:
Drug development and industrial pharmacy. 38(8)
The feasibility of using a liposome drug delivery system to formulate octylglycerol (OG) as a vaginal microbicide product was explored. A liposome formulation was developed containing 1% OG and phosphatidyl choline in a ratio that demonstrated in vit
Autor:
Brian L. Hood, Phalguni Gupta, Lisa C. Rohan, Alexandra B. Sassi, Katherine E. Bunge, Alexander M. Cole, Thomas P. Conrads
Publikováno v:
AIDS Research and Therapy, Vol 8, Iss 1, p 27 (2011)
AIDS Research and Therapy
AIDS Research and Therapy
Background RC-101, a cationic peptide retrocyclin analog, has in vitro activity against HIV-1. Peptide drugs are commonly prone to conformational changes, oxidation and hydrolysis when exposed to excipients in a formulation or biological fluids in th
Autor:
Carol Lackman-Smith, Nicole A. Rogers, Alan J. Waring, Alexander M. Cole, Yvonne Cosgrove-Sweeney, Piotr Ruchala, Alexandra B. Sassi, Dorothy L. Patton, Patrick M. Tarwater, Deena Ratner, Robert I. Lehrer, Phalguni Gupta, Lisa C. Rohan, Amy L. Cole, Bharat Ramratnam
Publikováno v:
PloS one, vol 5, iss 11
PLoS ONE, Vol 5, Iss 11, p e15111 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e15111 (2010)
PLoS ONE
Author(s): Cole, Alexander M; Patton, Dorothy L; Rohan, Lisa C; Cole, Amy L; Cosgrove-Sweeney, Yvonne; Rogers, Nicole A; Ratner, Deena; Sassi, Alexandra B; Lackman-Smith, Carol; Tarwater, Patrick; Ramratnam, Bharat; Ruchala, Piotr; Lehrer, Robert I;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db034964d5335f65bbd6ee394604302
https://escholarship.org/uc/item/262455ww
https://escholarship.org/uc/item/262455ww
Publikováno v:
Pharmaceutical research. 26(3)
Nanoparticles formulated from the biodegradable co-polymer poly(lactic-co-glycolic acid) (PLGA), were investigated as a drug delivery system to enhance tissue uptake, permeation, and targeting for PSC-RANTES anti-HIV-1 activity.PSC-RANTES nanoparticl
Autor:
Alexandra B. Sassi, Lisa C. Rohan
Publikováno v:
The AAPS journal. 11(1)
Microbicides have become a principal focus for HIV prevention strategies. The successful design of drug delivery systems for vaginal microbicide drug candidates brings with it a multitude of challenges. It is imperative that the chemical and physical
Autor:
Charles E. Isaacs, Alexandra B. Sassi, Lisa C. Rohan, Bernard J. Moncla, Phalguni Gupta, Sharon L. Hillier
Publikováno v:
Journal of pharmaceutical sciences. 97(8)
The increased incidence of HIV infection in women has identified a need to develop a female controlled method to prevent sexually transmitted infections (STIs), including HIV. Formulations have been developed in our laboratory for two potential micro