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pro vyhledávání: '"Alexandra Bähre"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Bladder cancer is a frequent malignancy and has a clinical need for new therapeutic approaches. Antibody and protein technologies came a long way in recent years and new engineering approaches were applied to generate innovative therapeutic entities
Externí odkaz:
https://doaj.org/article/2baf03aa60ca4d78ac97ae835d7c5f92
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Bladder cancer is a frequent malignancy and has a clinical need for new therapeutic approaches. Antibody and protein technologies came a long way in recent years and new engineering approaches were applied to generate innovative therapeutic entities
Publikováno v:
5.1 Airway Pharmacology and Treatment.
Monoclonal antibodies (mAb) have transformed medicine but their ∼160 kD molecular weight and fragility make inhalation technically difficult, limiting utility in lung disease. Lipocalin-1 (LCN1) is a 17kD endogenous non-glycosylated, nest-like prot
Autor:
Hartmut Goldschmidt, Sergey Kipriyanov, Thomas Moehler, Holger J. Schäfer, Marike J. J. G. Stassar, Alexandra Bähre, Björn Cochlovius, Jana Schlenzka, Axel Benner, Melvyn Little, Martin Kornacker
Publikováno v:
Anti-Cancer Drugs. 15:915-919
Combining different treatment strategies offers the possibility of improving treatment results for cancer patients. The aim of our study was therefore to investigate the combination of treatment of established s.c. human B non-Hodgkin's lymphoma in s
Autor:
Björn Cochlovius, Stefan Knackmuss, Sergey Kipriyanov, Melvyn Little, Alexandra Bähre, Fabrice Le Gall, Gerhard Moldenhauer, Holger J. Schäfer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(1)
To target NK cells against non-Hodgkin’s lymphoma, we constructed a bispecific diabody (BsDb) with reactivity against both human CD19 and FcγRIII (CD16). Bacterially produced CD19 × CD16 BsDb specifically interacted with both CD19+ and CD16+ cell
Publikováno v:
Immunology letters. 80(2)
ScOKT3-gammaDeltaIgM VAEVD is a recombinant chimeric anti-CD3 antibody variant consisting of the light and heavy variable binding domains of the OKT3 monoclonal antibody and the CH3 and CH4 domains of a human IgM mutation linked by a human IgG3 hinge