Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alexandra A. Tsitrina"'
Autor:
Noreen Halimani, Mikhail Nesterchuk, Alexandra A. Tsitrina, Marat Sabirov, Irina N. Andreichenko, Nataliya O. Dashenkova, Elizaveta Petrova, Alexey M. Kulikov, Timofei S. Zatsepin, Roman A. Romanov, Arsen S. Mikaelyan, Yuri V. Kotelevtsev
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Hepatic fibrosis remains a significant clinical challenge due to ineffective treatments. 4-methylumbelliferone (4MU), a hyaluronic acid (HA) synthesis inhibitor, has proven safe in phase one clinical trials. In this study, we aimed to amelio
Externí odkaz:
https://doaj.org/article/bf1761999a1a4425962a2dc2b2b8b341
Autor:
Alina S. Magnaeva, Anna V. Tregubova, Alexandra A. Tsitrina, Alexandra V. Asaturova, Marina V. Shamarakova, Guzal I. Tabeeva, Larisa S. Ezhova, Elena A. Kalinina, Vladimir K. Bozhenko
Publikováno v:
Гинекология, Vol 24, Iss 3, Pp 186-192 (2022)
Introduction. The main function of the endometrium is to create the optimal environment for embryo implantation, controlled by multicomponent signaling pathways. They are modulated by progesterone and estradiol acting through related estrogen recepto
Externí odkaz:
https://doaj.org/article/3437714d48cf44d995859beb7da5c132
Autor:
Anna V. Polikarpova, Tatiana V. Egorova, Evgenii A. Lunev, Alexandra A. Tsitrina, Svetlana G. Vassilieva, Irina M. Savchenko, Yuliya Y. Silaeva, Alexey V. Deykin, Maryana V. Bardina
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
The development of personalized medicine for genetic diseases requires preclinical testing in the appropriate animal models. GNAO1 encephalopathy is a severe neurodevelopmental disorder caused by heterozygous de novo mutations in the GNAO1 gene. GNAO
Externí odkaz:
https://doaj.org/article/23346d150ced45478ada50824f70075c
Autor:
Noreen Halimani, Mikhail Nesterchuk, Irina N. Andreichenko, Alexandra A. Tsitrina, Andrey Elchaninov, Anastasia Lokhonina, Timur Fatkhudinov, Nataliya O. Dashenkova, Vera Brezgina, Timofei S. Zatsepin, Arsen S. Mikaelyan, Yuri V. Kotelevtsev
Publikováno v:
Cells, Vol 11, Iss 16, p 2498 (2022)
Autologous macrophage transfer is an emerging platform for cell therapy. It is anticipated that conventional macrophage reprogramming based on ex vivo polarization using cytokines and ligands of TLRs may enhance the therapeutic effect. We describe an
Externí odkaz:
https://doaj.org/article/15fdbb37cfd446388d971bcc2e8cf3f5
Autor:
Sergei K. Trufanov, Elena Yu. Rybakova, Piotr P. Avdonin, Alexandra A. Tsitrina, Irina L. Zharkikh, Nikolay V. Goncharov, Richard O. Jenkins, Pavel V. Avdonin
Publikováno v:
Cells, Vol 8, Iss 10, p 1144 (2019)
Second messenger nicotinic acid adenine dinucleotide phosphate (NAADP) triggers Ca2+ release via two-pore channels (TPCs) localized in endolysosomal vesicles. The aim of the present work is to evaluate the role of TPCs in the action of norepinephrine
Externí odkaz:
https://doaj.org/article/afbc9e2aa2e54fb280188e6de720ad61
Autor:
Pavel V. Avdonin, Elena Yu. Rybakova, Piotr P. Avdonin, Sergei K. Trufanov, Galina Yu. Mironova, Alexandra A. Tsitrina, Nikolay V. Goncharov
Publikováno v:
Cells, Vol 8, Iss 2, p 196 (2019)
In this study, we investigated the effects of NAD(P)H oxidase (NOX) inhibitor VAS2870 (3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine) on the histamine-induced elevation of free cytoplasmic calcium concentration ([Ca2+]i) and the sec
Externí odkaz:
https://doaj.org/article/3f70f47e463d4e6094624e33ce9f5020
Autor:
Anastasiia Yu. Sapach, Olga A. Sindeeva, Mikhail V. Nesterchuk, Alexandra A. Tsitrina, Oksana A. Mayorova, Ekaterina S. Prikhozhdenko, Roman A. Verkhovskii, Arsen S. Mikaelyan, Yuri V. Kotelevtsev, Gleb B. Sukhorukov
Publikováno v:
ACS Applied Materials & Interfaces. 14:51579-51592
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a005e9eddfbde6d410d50d8c8e955d
https://doi.org/10.1021/acsami.2c12004
https://doi.org/10.1021/acsami.2c12004
Autor:
Anastasiia Yu, Sapach, Olga A, Sindeeva, Mikhail V, Nesterchuk, Alexandra A, Tsitrina, Oksana A, Mayorova, Ekaterina S, Prikhozhdenko, Roman A, Verkhovskii, Arsen S, Mikaelyan, Yuri V, Kotelevtsev, Gleb B, Sukhorukov
Publikováno v:
ACS applied materialsinterfaces. 14(46)
A new promising trend in personalized medicine is the use of autologous cells (macrophages or stem cells) for cell-based therapy and also as a "Trojan horse" for targeted delivery of a drug carrier. The natural ability of macrophages for chemotaxis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b14195b9bdc15f21764eb82ebe56a525
https://pubmed.ncbi.nlm.nih.gov/36367877
https://pubmed.ncbi.nlm.nih.gov/36367877
Autor:
Mikhail V. Nesterchuk, A. S. Mikaelyan, Nataliya O Dashenkova, V. P. Khilya, Irina N Andreichenko, Alexandra A Tsitrina, Vera Shashkovskaya, Dmitry N. Ivankov, Dmitry I Maltsev, Igor V Krasylov, Viktoria S. Moskvina, Yuri Kotelevtsev, Elena V Bulgakova
Publikováno v:
Glycobiology
Elevated plasma levels of hyaluronic acid (HA) is a disease marker in liver pathology and other inflammatory disorders. Inhibition of HA synthesis with coumarin 4-methylumbelliferone (4MU) has a beneficial effect in animal models of fibrosis, inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab651c990af92492155d6832a71d60bb
http://europepmc.org/articles/PMC8434796
http://europepmc.org/articles/PMC8434796
Autor:
Alexandra A. Tsitrina, Noreen Halimani, Irina N. Andreichenko, Marat Sabirov, Mikhail Nesterchuk, Nataliya O. Dashenkova, Roman Romanov, Elena V. Bulgakova, Arsen Mikaelyan, Yuri Kotelevtsev
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2129
Volume 24
Issue 3
Pages: 2129
4-methylumbelliferone (4MU) is a well-known hyaluronic acid synthesis inhibitor and an approved drug for the treatment of cholestasis. In animal models, 4MU decreases inflammation, reduces fibrosis, and lowers body weight, serum cholesterol, and insu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df41a3e95c144422665948b2d5df0154
https://doi.org/10.3390/ijms24032129
https://doi.org/10.3390/ijms24032129