Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexandra A. Kroshilina"'
Autor:
Marta Olah, Vilas Menon, Naomi Habib, Mariko F. Taga, Yiyi Ma, Christina J. Yung, Maria Cimpean, Anthony Khairallah, Guillermo Coronas-Samano, Roman Sankowski, Dominic Grün, Alexandra A. Kroshilina, Danielle Dionne, Rani A. Sarkis, Garth R. Cosgrove, Jeffrey Helgager, Jeffrey A. Golden, Page B. Pennell, Marco Prinz, Jean Paul G. Vonsattel, Andrew F. Teich, Julie A. Schneider, David A. Bennett, Aviv Regev, Wassim Elyaman, Elizabeth M. Bradshaw, Philip L. De Jager
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Imbalance of microglial phenotypes in the aging brain might underlie their involvement in late onset neurodegenerative diseases. Here we report the population structure of microglia in the aged human brain and the reduction of a particular microglia
Externí odkaz:
https://doaj.org/article/70f5aedb5f20425e97be8410947e4a81
Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.
Autor:
Roostaei T; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Klein HU; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Ma Y; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Felsky D; Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada., Kivisäkk P; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Connor SM; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Kroshilina A; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Yung C; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA., Kaskow BJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Shao X; Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA, USA., Rhead B; Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA, USA., Ordovás JM; Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA., Absher DM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA., Liu J; Advanced Science Research Center at the Graduate Center, Neuroscience Initiative, City University of New York, New York, NY, USA., Patsopoulos N; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Barcellos LF; Genetic Epidemiology and Genomics Laboratory, University of California, Berkeley, CA, USA., Weiner HL; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., De Jager PL; Center for Translational and Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's disease and the Aging brain, Columbia University Irving Medical Center, New York, NY, USA. pld2115@cumc.columbia.edu.
Publikováno v:
Nature communications [Nat Commun] 2021 Dec 06; Vol. 12 (1), pp. 7078. Date of Electronic Publication: 2021 Dec 06.
Autor:
Taga M; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, USA., Petyuk VA; Pacific Northwest National Laboratory, Richland, WA, USA., White C; Cell Circuits Program, Broad Institute, Cambridge, MA, USA., Marsh G; Biogen, 225 Binney St, Cambridge, MA, 02142, USA., Ma Y; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA., Klein HU; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, USA., Connor SM; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, USA., Kroshilina A; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA., Yung CJ; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA., Khairallah A; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA., Olah M; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, USA., Schneider J; Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Karhohs K; Imaging Platform, Broad Institute, Cambridge, MA, USA., Carpenter AE; Imaging Platform, Broad Institute, Cambridge, MA, USA., Ransohoff R; Third Rock Ventures, 29 Newbury Street, Suite 301, Boston, MA, 02116, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Bennett DA; Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Crotti A; Biogen, 225 Binney St, Cambridge, MA, 02142, USA., Bradshaw EM; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA.; Cell Circuits Program, Broad Institute, Cambridge, MA, USA., De Jager PL; Center for Translational & Computational Neuroimmunology, Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, 630 West 168th st, PH19-311, New York, NY, 10032, USA. pld2115@cumc.columbia.edu.; Cell Circuits Program, Broad Institute, Cambridge, MA, USA. pld2115@cumc.columbia.edu.
Publikováno v:
Molecular neurodegeneration [Mol Neurodegener] 2020 Jul 29; Vol. 15 (1), pp. 44. Date of Electronic Publication: 2020 Jul 29.
Autor:
Ruan C; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Sun L; Department of Anesthesiology, Columbia University, New York, NY, USA., Kroshilina A; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Beckers L; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., De Jager P; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Bradshaw EM; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA., Hasson SA; Pfizer Inc., Cambridge, MA, USA; Amgen Research, Cambridge, MA, USA., Yang G; Department of Anesthesiology, Columbia University, New York, NY, USA., Elyaman W; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University, New York, NY, USA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA. Electronic address: we2152@cumc.columbia.edu.
Publikováno v:
Brain, behavior, and immunity [Brain Behav Immun] 2020 Jan; Vol. 83, pp. 180-191. Date of Electronic Publication: 2019 Oct 08.