Výsledky vyhledávání - "Alexandra A. Holubec"

Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition

Autor: Akio Kakefuda, Ran N. Tao, Joshua J. Day, Masami Ohtsuka, John L. Wood, Julie A. Dixon, Noah A. Dieterich, Matthew W. Weiss, Rishi G. Vaswani, Hidenori Ohki, Brian M. Stoltz, Sarah E. Reisman, David Freeman, Alexandra A. Holubec, Brian D. Doan, Munenori Inoue

Described is the construction of the N-methylwelwitindolinone C core via an efficient strategy that employs a sequential rhodium carbenoid-mediated O–H insertion, Claisen rearrangement and transannular [3+2] nitrone cycloaddition.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c485147a4fb835078c70257d99e77d
https://europepmc.org/articles/PMC2924776/

Zobrazit plný text záznamu

ChemInform Abstract: Development of a Rhodium Carbenoid Initiated Claisen Rearrangement for the Enantioselective Synthesis of α-Hydroxy Carbonyl Compounds

Autor: John L. Wood, Derek A. Pflum, Brian M. Stoltz, Alexandra A. Holubec, George A. Moniz, Hans-Juergen Dietrich

Publikováno v: ChemInform. 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efb9489e0312be4b03b19ece8e1b73e5
https://doi.org/10.1002/chin.199929024

Zobrazit plný text záznamu

Application of Reactive Enols in Synthesis: A Versatile, Efficient, and Stereoselective Construction of the Welwitindolinone Carbon Skeleton

Autor: Matthew M. Weiss, Brian D. Doan, John L. Wood, Mohammed F. Shamji, Alexandra A. Holubec, and Jennifer M. Chen, Timothy P. Heffron, Brian M. Stoltz, Julie A. Dixon

Publikováno v: Journal of the American Chemical Society. 121:6326-6327

Recently, efforts to identify biologically important natural products from cyanobacteria resulted in the isolation of several welwitindolinone alkaloids, two of which have been identified as antagonists of the P-glycoprotein P-170 and hence as MDRrev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9766ea1709322f72ca505a790e95b025
https://doi.org/10.1021/ja991022s

Zobrazit plný text záznamu

Development of a Rhodium Carbenoid-Initiated Claisen Rearrangement for the Enantioselective Synthesis of α-Hydroxy Carbonyl Compounds

Autor: John L. Wood, George A. Moniz, Hans-Juergen Dietrich, Brian M. Stoltz, Derek A. Pflum, Alexandra A. Holubec

Publikováno v: Journal of the American Chemical Society. 121:1748-1749

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b22a85633b8aad2c1647d383c4e9e680
https://doi.org/10.1021/ja983294l

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání