In vivo Expression of the Murine c-myc Oncogene Driven by the Rat Surfactant Protein A Promoter

Autor: J. Bourbon, Alexandra A. Henrion, T. Lacaze-Masmonteil, A Kahn, A. Porteu, Michel Raymondjean, C. Fraslon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::903d6ba67ef9e784a399f4db90174691
https://doi.org/10.1159/000423036

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

Autor: Monique Fabre, Alexandre Mignon, Arlette Porteu, Nicolas Rouquet, Paule Varlet, Axel Kahn, Thierry Jo Molina, Virginie Joulin, Alexandra A. Henrion, Benoit Viollet, Virginie Lacronique, Dldier Bouscary

Publikováno v: Nature Medicine. 2:80-86

Fas is an apoptosis-signalling cell surface antigen that has been shown to trigger cell death upon specific ligand or antibody binding. Treatment of mice with an anti-Fas antibody causes fulminant hepatic failure due to massive apoptosis. To test a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21d9f49a470bc1535f6a9abe7e6a83a
https://doi.org/10.1038/nm0196-80

Differential roles of upstream stimulatory factors 1 and 2 in the transcriptional response of liver genes to glucose

Autor: Marta Casado, Axel Kahn, Virginie S. Vallet, Michel Raymondjean, Alexandra A. Henrion, Danielle Bucchini, Sophie Vaulont

Publikováno v: The Journal of biological chemistry. 273(32)

USF1 and USF2 are ubiquitous transcription factors of the basic helix-loop-helix leucine zipper family. They form homo- and heterodimers and recognize a CACGTG motif termed E box. In the liver, USF binding activity is mainly accounted for by the USF1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d5451a4eb6a9be34c1599cb2dc1a38
https://pubmed.ncbi.nlm.nih.gov/9685363

Mouse USF1 gene cloning: comparative organization within the c-myc gene family

Autor: Sophie Vaulont, Alexandra A. Henrion, Michel Raymondjean, Axel Kahn

Publikováno v: Mammalian genome : official journal of the International Mammalian Genome Society. 7(11)

Upstream stimulatory factors (USF/MLTF) belong to the c-myc family of transcription factors. Through binding to target DNA as dimers, the ubiquitous USF proteins regulate a variety of genes. USF proteins are encoded by two genes, USF1 and USF2. Prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0fa27cd0ef00bdf589fa39e46de31d
https://pubmed.ncbi.nlm.nih.gov/8875887

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.

Autor: Lahrouchi N; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands., George A; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, Bethesda, MD, 20892, USA., Ratbi I; Centre de Recherche en Génomique des Pathologies Humaines (GENOPATH), Faculté de Médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Schneider R; Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Elalaoui SC; Centre de Recherche en Génomique des Pathologies Humaines (GENOPATH), Faculté de Médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Moosa S; Institute of Human Genetics, University Medical Center Goettingen, 37073, Goettingen, Germany.; Boston Children's Hospital and Harvard Medical School, Boston, MA, 02215, USA., Bharti S; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, Bethesda, MD, 20892, USA.; Unit on Ocular & Stem Cell Translational Research, National Eye Institute, NIH, Bethesda, MD, 20892, USA., Sharma R; Unit on Ocular & Stem Cell Translational Research, National Eye Institute, NIH, Bethesda, MD, 20892, USA., Abu-Asab M; Section of Histopathology, National Eye Institute, NIH, Bethesda, MD, 20892, USA., Onojafe F; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, Bethesda, MD, 20892, USA., Adadi N; Centre de Recherche en Génomique des Pathologies Humaines (GENOPATH), Faculté de Médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Lodder EM; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands., Laarabi FZ; Département de génétique médicale, Institut National d'Hygiène, BP 769 Agdal, 10090, Rabat, Morocco., Lamsyah Y; Service d'Ophtalmologie B, Hôpital des Spécialités, CHU Rabat, Faculté de médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Elorch H; Service d'Ophtalmologie B, Hôpital des Spécialités, CHU Rabat, Faculté de médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Chebbar I; Service d'Ophtalmologie B, Hôpital des Spécialités, CHU Rabat, Faculté de médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Postma AV; Amsterdam UMC, University of Amsterdam, Department of Anatomy, Embryology & Physiology, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam, The Netherlands., Lougaris V; Pediatrics Clinic and Institute for Molecular Medicine 'A. Nocivelli', Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia, 25123, Brescia, Italy., Plebani A; Pediatrics Clinic and Institute for Molecular Medicine 'A. Nocivelli', Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia, 25123, Brescia, Italy., Altmueller J; Cologne Center for Genomics University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, 50931, Germany.; Institute of Human Genetics, University of Cologne, 50931, Cologne, Germany., Kyrieleis H; Department of Pediatrics, Bethanien Hospital, Cologne, 42699, Germany., Meiner V; Department of Human Genetics and Metabolic Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, 91120, Israel., McNeill H; Department of Developmental Biology, Washington University School of Medicine, St. Louis, 63110, MO, USA., Bharti K; Unit on Ocular & Stem Cell Translational Research, National Eye Institute, NIH, Bethesda, MD, 20892, USA., Lyonnet S; Laboratory of embryology and genetics of human malformation, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR 1163, Paris Descartes-Sorbonne Paris Cité University, Institut Imagine, Paris, 75015, France., Wollnik B; Institute of Human Genetics, University Medical Center Goettingen, 37073, Goettingen, Germany., Henrion-Caude A; INSERM UMR-781, Département de Génétique, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris (APHP), Paris, 75015, France., Berraho A; Service d'Ophtalmologie B, Hôpital des Spécialités, CHU Rabat, Faculté de médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco., Hildebrandt F; Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Bezzina CR; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Meibergdreef 9, Amsterdam, 1105AZ, The Netherlands. c.r.bezzina@amc.uva.nl., Brooks BP; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, Bethesda, MD, 20892, USA. brooksb@nei.nih.gov., Sefiani A; Centre de Recherche en Génomique des Pathologies Humaines (GENOPATH), Faculté de Médecine et de Pharmacie, Mohammed V University of Rabat, 10100, Rabat, Morocco. sefianigen@hotmail.com.; Département de génétique médicale, Institut National d'Hygiène, BP 769 Agdal, 10090, Rabat, Morocco. sefianigen@hotmail.com.

Publikováno v: Nature communications [Nat Commun] 2019 Mar 12; Vol. 10 (1), pp. 1180. Date of Electronic Publication: 2019 Mar 12.