Bariatric surgery induces a new gastric mucosa phenotype with increased functional glucagon-like peptide-1 expressing cells

Autor: Lara Ribeiro-Parenti, Anne-Charlotte Jarry, Jean-Baptiste Cavin, Alexandra Willemetz, Johanne Le Beyec, Aurélie Sannier, Samira Benadda, Anne-Laure Pelletier, Muriel Hourseau, Thibaut Léger, Bastien Morlet, Anne Couvelard, Younes Anini, Simon Msika, Jean-Pierre Marmuse, Sévérine Ledoux, Maude Le Gall, André Bado

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

GLP-1 is a gastrointestinal peptide that regulates gastric acid secretion and emptying, and due to the rapid degradation of intestinally secreted GLP-1 local gastric production has been suggested. Here the authors report the presence of GLP-1 express

Externí odkaz: https://doaj.org/article/8b4354bf0d9d4f7480bedf22941d90e0

Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection

Autor: François Canonne-Hergaux, Alexandra Willemetz, Sean Beatty, Etienne Richer, Aude Rubio, Anne Auriac, Ruth J. Milkereit, Olivier Thibaudeau, Sophie Vaulont, Danielle Malo

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Retention of iron in tissue macrophages via upregulation of hepcidin (HAMP) and downregulation of the iron exporter ferroportin (FPN) is thought to participate in the establishment of anemia of inflammation after infection. However, an upregulation o

Externí odkaz: https://doaj.org/article/a0eda4eda26d42eaa102226c39f63c4f

Shortening the Biliopancreatic Limb Length of One Anastomosis Gastric Bypass Maintains Glucose Homeostasis Improvement with Limited Weight Loss

Autor: Lara Ribeiro-Parenti, Hounayda El Jindi, Alexandra Willemetz, Matthieu Siebert, Nathalie Kapel, Johanne Le Beyec, André Bado, Maude Le Gall

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 17; Pages: 4976

One anastomosis gastric bypass (OAGB) is associated with similar metabolic improvements and weight loss as Roux-en-Y gastric bypass (RYGB). However, this bariatric procedure is still controversial as it is suspected to result in undernutrition. Reduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fcf60df91f80dd76aad61cc617c138
https://doi.org/10.3390/jcm11174976

Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium

Autor: Giusy Sala, Riccardo Ghidoni, Monica Thelestam, Stuart E.H. Moore, Christelle Durrant, Jana I. Fuehring, Agnès Rötig, Alexandra Willemetz, Abram Katz, D Chretien, Myriam Ermonval

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6, p 2028 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2020, 21 (6), pp.2028. ⟨10.3390/ijms21062028⟩
Volume 21
Issue 6
International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2028. ⟨10.3390/ijms21062028⟩

UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase. Chinese hamster lu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfe91ea1573ac5fc8e267238aae14a8
https://www.mdpi.com/1422-0067/21/6/2028

Subcellular localization of iron and heme metabolism related proteins at early stages of erythrophagocytosis.

Autor: Constance Delaby, Christiane Rondeau, Cécile Pouzet, Alexandra Willemetz, Nathalie Pilard, Michel Desjardins, François Canonne-Hergaux

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e42199 (2012)

BACKGROUND: Senescent red blood cells (RBC) are recognized, phagocytosed and cleared by tissue macrophages. During this erythrophagocytosis (EP), RBC are engulfed and processed in special compartments called erythrophagosomes. We previously described

Externí odkaz: https://doaj.org/article/71afc09a348c44d68eac144d9d35f266