Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alexandra, Probst"'
Autor:
Lorencia Taljaard, Alexandra Probst, Robert Tornow, Jennifer Keiser, Richard K. Haynes, Frank van der Kooy
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 3, Pp 100279- (2022)
Background: Schistosomiasis, a neglected tropical disease, imposes substantial health and economic burdens on impoverished groups living in predominantly rural areas. Praziquantel (PZQ) is the only drug available for treatment, and it is not complete
Externí odkaz:
https://doaj.org/article/505302c9eb5b43359d033ce34cbf9493
Autor:
Alexandra Probst, Thi N. Nguyen, Nelly El-Sakkary, Danielle Skinner, Brian M. Suzuki, Frederick S. Buckner, Michael H. Gelb, Conor R. Caffrey, Anjan Debnath
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The protozoan parasite Entamoeba histolytica can induce amebic colitis and amebic liver abscess. First-line drugs for the treatment of amebiasis are nitroimidazoles, particularly metronidazole. Metronidazole has side effects and potential drug resist
Externí odkaz:
https://doaj.org/article/c2d0be25852b45c0916199092e9373e5
Publikováno v:
Royal Society Open Science, Vol 5, Iss 8 (2018)
Externí odkaz:
https://doaj.org/article/33bee51835384eefbbc35019bd420702
Publikováno v:
Royal Society Open Science, Vol 5, Iss 7 (2018)
Photogrammetry-based three-dimensional reconstruction of objects is becoming increasingly appealing in research areas unrelated to computer vision. It has the potential to facilitate the assessment of forest inventory-related parameters by enabling o
Externí odkaz:
https://doaj.org/article/df1823ea69dd44ba8ddde498e2d7567f
Autor:
Alexandra Probst, Daniela Hofmann, Olga S. Fedorova, Sofia V. Mazeina, Tatiana S. Sokolova, Ekaterina Golovach, Jennifer Keiser
Publikováno v:
Antimicrob Agents Chemother
Opisthorchiasis due to the liver fluke Opisthorchis felineus is highly prevalent in rural regions of Western Siberia, causing severe liver and bile duct maladies. Praziquantel administered as a three-dose regimen is the only drug used to treat O. fel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed1dc42a4438f523ac1a5d66d5904d6
https://europepmc.org/articles/PMC9578388/
https://europepmc.org/articles/PMC9578388/
Publikováno v:
Advances in parasitology. 117
Schistosomiasis is a poverty-associated tropical disease caused by blood dwelling trematodes that threaten approximately 10% of the world population. Praziquantel, the sole drug currently available for treatment, is insufficient to eliminate the dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8de4ea59041a1708b3e249da414f0bfa
https://pubmed.ncbi.nlm.nih.gov/35878949
https://pubmed.ncbi.nlm.nih.gov/35878949
Autor:
Kelly Chibale, Alexandra Probst, Jennifer Keiser, Kelly Chisanga, Godwin Akpeko Dziwornu, Cécile Haeberli
Publikováno v:
ACS Infectious Diseases. 7:1032-1043
Praziquantel is the only widely available drug to treat schistosomiasis. With very few candidates currently in the drug development pipeline, there is an urgent need to discover and develop novel antischistosomal drugs. In this regard, the pyrido[1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00b40fd85b8e5fb3812a8cdfaa39ad40
https://doi.org/10.1021/acsinfecdis.0c00278
https://doi.org/10.1021/acsinfecdis.0c00278
Publikováno v:
Advances in Parasitology ISBN: 9780323989497
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2570f4cb7dda1782f599408682e2c66e
https://doi.org/10.1016/bs.apar.2022.05.002
https://doi.org/10.1016/bs.apar.2022.05.002
Publikováno v:
Antimicrobial Agents and Chemotherapy. 65
In recent years, N,N'-diarylureas have emerged as a promising chemotype for the treatment of schistosomiasis, a parasite-caused disease that poses a considerable health burden to millions of people worldwide. Here, we report a novel series of N,N'-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d5364577a5720c74c21a194d171fb1
https://doi.org/10.1128/aac.00615-21
https://doi.org/10.1128/aac.00615-21
Autor:
Alexandra, Probst, Kelly, Chisanga, Godwin Akpeko, Dziwornu, Cécile, Haeberli, Jennifer, Keiser, Kelly, Chibale
Publikováno v:
ACS infectious diseases. 7(5)
Praziquantel is the only widely available drug to treat schistosomiasis. With very few candidates currently in the drug development pipeline, there is an urgent need to discover and develop novel antischistosomal drugs. In this regard, the pyrido[1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45304eb11fe8479a407b64004aa23108
https://pubmed.ncbi.nlm.nih.gov/32786285
https://pubmed.ncbi.nlm.nih.gov/32786285