Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Alexandra, Kehl"'
Autor:
Keijiro Mizukami, Angella Dorsey-Oresto, Karthik Raj, Anna Eringis, Eva Furrow, Errolyn Martin, Daisuke Yamanaka, Alexandra Kehl, Ana Kolicheski, Vidhya Jagannathan, Tosso Leeb, Michail S. Lionakis, Urs Giger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Mammals are generally resistant to Mycobacterium avium complex (MAC) infections. We report here on a primary immunodeficiency disorder causing increased susceptibility to MAC infections in a canine breed. Adult Miniature Schnauzers developin
Externí odkaz:
https://doaj.org/article/a177f7a1f6b44f2e9545cce2574d3ba7
Autor:
Argyrios Ginoudis, Bertrand Canard, Alexandra Kehl, Urs Giger, Christos Koutinas, Stella Christoforaki, Erasmia Smyroglou, Zoe Polizopoulou, Mathios E. Mylonakis
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 1, Pp 358-362 (2024)
Abstract An adult domestic short‐haired feline leukemia virus‐infected cat was referred for kidney failure and worsening anemia requiring transfusions. ABC blood typing was performed with an immunochromatographic strip assay at different occasion
Externí odkaz:
https://doaj.org/article/665ba09e9ee54f8889abec49b3c1dacd
Autor:
Annika Bartel, Heike Aupperle-Lellbach, Alexandra Kehl, Silvia Weidle, Leonore Aeschlimann, Robert Klopfleisch, Simone de Brot
Publikováno v:
Veterinary Sciences, Vol 11, Iss 11, p 584 (2024)
Alterations of the BRAF gene and the resulting changes in the BRAF protein are one example of molecular cancer profiling in humans and dogs. We tested 227 samples of canine carcinomas from different anatomical sites (anal sac (n = 23), intestine (n =
Externí odkaz:
https://doaj.org/article/dfc357bd42564118b182bab3f9e260bf
Autor:
Jana van Renen, Alexandra Kehl, Gesine Buhmann, Lara A. Matiasek, Yury Zablotski, Andrea Fischer
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionNecrotizing meningoencephalitis (NME) in pugs is a potentially fatal disease, which needs lifelong treatment with immunosuppressive or immunomodulatory drugs and shares parallels with acute fulminating multiple sclerosis. Genetic variants
Externí odkaz:
https://doaj.org/article/14c8b3ddadb14dd48803f1d0bda5e20e
Autor:
Alexandra Kehl, Henrike Kuder, Lily Parkinson, Amie Koenig, Ines Langbein-Detsch, Elisabeth Mueller, Urs Giger
Publikováno v:
Animals, Vol 14, Iss 16, p 2442 (2024)
Different blood group systems have been characterized in people and other mammals. In domestic cats, the ABC blood group system plays the most important clinical role and has been investigated extensively—from the phenotype to the molecular genetic
Externí odkaz:
https://doaj.org/article/ce6290eb2a834df7a7a1374e2144154b
Publikováno v:
Veterinary Sciences, Vol 11, Iss 5, p 199 (2024)
Molecular biomarkers are central to personalised medicine for human cancer patients. It is gaining traction as part of standard veterinary clinical practice for dogs and cats with cancer. Molecular biomarkers can be somatic or germline genomic altera
Externí odkaz:
https://doaj.org/article/0bf0230f197e48ac8d616e081d717c53
Publikováno v:
Animals, Vol 14, Iss 5, p 769 (2024)
Genetic molecular testing is starting to gain traction as part of standard clinical practice for dogs with cancer due to its multi-faceted benefits, such as potentially being able to provide diagnostic, prognostic and/or therapeutic information. Howe
Externí odkaz:
https://doaj.org/article/54a741f0d72a4ccc8a8402cdadaca79c
Autor:
Leonore Küchler, Caroline Posthaus, Kathrin Jäger, Franco Guscetti, Louise van der Weyden, Wolf von Bomhard, Jarno M. Schmidt, Dima Farra, Heike Aupperle-Lellbach, Alexandra Kehl, Sven Rottenberg, Simone de Brot
Publikováno v:
Animals, Vol 13, Iss 15, p 2404 (2023)
In dogs, the BRAF mutation (V595E) is common in bladder and prostate cancer and represents a specific diagnostic marker. Recent advantages in artificial intelligence (AI) offer new opportunities in the field of tumour marker detection. While AI histo
Externí odkaz:
https://doaj.org/article/fe40c346391d42939a8929ed25fcd364
Publikováno v:
Animals, Vol 13, Iss 10, p 1694 (2023)
Grading, immunohistochemistry and c-kit mutation status are criteria for assessing the prognosis and therapeutic options of canine cutaneous mast cell tumours (MCTs). As a subset, canine digital MCTs have rarely been explored in this context. Therefo
Externí odkaz:
https://doaj.org/article/262a422773df4253bf1605352ee8ddb9
Autor:
Alexandra Kehl, Mario Valkai, Anna-Lena Van de Weyer, Maria Brockmann, Katja Steiger, Benjamin Schusser, Heike Aupperle-Lellbach
Publikováno v:
Veterinary Sciences, Vol 10, Iss 2, p 125 (2023)
Most canine intestinal tumours are B-cell or T-cell lymphomas or carcinomas. They have to be distinguished from cases of enteritis. Non-invasive biomarkers such as miRNAs would be a step towards faster diagnosis. The aim of this study was to investig
Externí odkaz:
https://doaj.org/article/0ce46aaf08424be4a03d4e12ddbb6b7b