Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Alexandr Jegorov"'
Publikováno v:
CyTA - Journal of Food, Vol 18, Iss 1, Pp 644-652 (2020)
Beauverolides are hydrophobic cyclodepsipeptides that inhibit sterol O-acyltransferases and calmodulin, thereby reducing senile plaques in Alzheimer’s disease and preventing foam cell formation in atherosclerosis. Other sterol O-acyltransferase inh
Externí odkaz:
https://doaj.org/article/f00b350141b04b83ac1341bb7dd104af
Publikováno v:
Molecules, Vol 24, Iss 14, p 2548 (2019)
An aminoborane side product from the nicergoline manufacture process was identified by single-crystal X-ray diffraction. As boranes of pharmaceutical molecules are quite rare, the binding potential of the BH3 group was investigated and compared with
Externí odkaz:
https://doaj.org/article/7a12a48bc0224061ac7577f6c8df563e
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 6, Pp 879-880 (2016)
In the paper by Rohlicek et al. [Acta Cryst. (2009), E65, o1325–o1326], one H atom was placed incorrectly.
Externí odkaz:
https://doaj.org/article/edc94dd6389440488c3721ead782a580
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 12, Pp o3252-o3253 (2009)
The title compound {systematic name: 9,10-didehydro-N-[1-(hydroxymethyl)propyl]-d-lysergamide maleate}, C20H26N3O2+·C4H3O4−, contains a large rigid ergolene group. This group consists of an indole plane connected to a six-membered carbon ring adop
Externí odkaz:
https://doaj.org/article/6ee2d38c09504ba3995f081616b1fd3e
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 6, Pp o1325-o1326 (2009)
In the title compound [systematic name 5-deoxy-5-fluoro-N-(pentyloxycarbonyl)cytidine], C15H22FN3O6, the pentyl chain is disordered over two positions with refined occupancies of 0.53 (5) and 0.47 (5). The furan ring assumes an envelope conformation.
Externí odkaz:
https://doaj.org/article/1c8ff435ad1d4f9dbe722c1fe6a3c34b
Publikováno v:
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials. 78:781-788
Validation of a method for distinguishing between salts and cocrystals based on dispersion-corrected density functional theory is presented. Existing related works (van de Streek & Neumann, 2010; LeBlanc et al., 2018) indicate that this approach is p
Autor:
Samuel Mach, Jan Čejka, Václav Eigner, Alexandr Jegorov, Jakub Zápal, Marek Kuzma, Zdeněk Šimek
Publikováno v:
Environmental Science and Pollution Research. 26:34896-34904
Twenty juvenile individuals of brown bullhead (Ameiurus nebulosus), average weight 77 g, were fed by abiraterone acetate prodrug dissolved in olive oil via gastric probe. Dose applied was 3 mg/10 g fish weight. After feeding, they were let out into a
Autor:
Alexandr Jegorov, Pavel Vraspir, Andrew N. Fitch, Jan Rohlíček, Simona Žižková, Pavel Kolesa, Jiri Czernek, Jiri Brus, Michal Hušák
Publikováno v:
Crystal Growth & Design. 19:4625-4631
The determination of crystal structures from powder X-ray diffraction (PXRD) data by using direct-space methods is significantly limited by the degrees of conformational freedom (DOF). This limit c...
Autor:
Jiří Czernek, Alexandr Jegorov, Jan Rohlíček, Libor Kobera, Andrew N. Fitch, Michal Hušák, Jiří Brus
Publikováno v:
Crystal Growth & Design. 18:3616-3625
Uncertainties in the structure determination of peptide analogs of boronic acid, exacerbated by the many coordination modes of boron, represent an obstacle in understanding their role in living organisms and thus also in developing the next generatio
Autor:
Alexandr Jegorov, Frank Lehmann, Jens Geier, Libor Kobera, Martina Urbanova, Wolfgang Albrecht, Jiří Brus, Jiri Czernek
Publikováno v:
Molecular Pharmaceutics. 14:2070-2078
A general, easy-to-implement strategy for mapping the structure of organic phases integrated in mesoporous silica drug delivery devices is presented. The approach based on a few straightforward solid-state NMR techniques has no limitations regarding