Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alexandr A, Romanko"'
Autor:
Anna P. Sokolenko, Luisa V. Sultanova, Ilya A. Stepanov, Alexandr A. Romanko, Aigul R. Venina, Tatiana N. Sokolova, Hedi S. Musayeva, Marina Ya. Tovgereeva, Mareta Kh. Magomedova, Khusein U. Akhmatkhanov, Elisa I. Vagapova, Elkhan A. Suleymanov, Elena V. Vasilyeva, Elvina Kh. Bakaeva, Ilya V. Bizin, Svetlana N. Aleksakhina, Evgeny N. Imyanitov
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 3167-3171 (2023)
Abstract Coding sequences of BRCA1, BRCA2, ATM, TP53, and PALB2 genes were analyzed in 68 consecutive Chechen patients with high‐grade serous ovarian cancer (HGSOC). Pathogenic BRCA1/2 variants were identified in 15 (22%) out of 68 HGSOC cases. Nin
Externí odkaz:
https://doaj.org/article/f722a1ada1774d7089bbe69758a94d6b
Autor:
Natalia V. Mitiushkina, Alexandr A. Romanko, Elena V. Preobrazhenskaya, Vladislav I. Tiurin, Tatiana I. Ermachenkova, Alexandr S. Martianov, Rimma S. Mulkidjan, Tatiana N. Sokolova, Maksim M. Kholmatov, Ilya V. Bizin, Alexandr O. Ivantsov, Olga S. Yatsuk, Olga A. Zaitseva, Aglaya G. Iyevleva, Ekatherina Sh. Kuligina, Evgeny N. Imyanitov
Publikováno v:
Cancer Medicine, Vol 11, Iss 17, Pp 3226-3237 (2022)
Abstract Background Despite the progress in the development of next‐generation sequencing (NGS), diagnostic PCR assays remain to be utilized in clinical routine due to their simplicity and low cost. Tests for 5′‐/3′‐end mRNA unbalanced expr
Externí odkaz:
https://doaj.org/article/d38a620319e847078e9a0ddad75d9206
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 50, Iss 1, Pp 1-12 (2022)
Molecular genetic diagnostics is an essential element to plan for management of colorectal cancer (CRC) patients. The choice of systemic treatment for CRC is impossible without molecular testing of the tumor. For instance, the assessment of the KRAS
Externí odkaz:
https://doaj.org/article/848babb684154534b767c29709cb518b
Autor:
Sergey V. Orlov, Aglaya G. Iyevleva, Elena A. Filippova, Alexandra M. Lozhkina, Svetlana V. Odintsova, Tatiana N. Sokolova, Natalia V. Mitiushkina, Vladislav I. Tiurin, Elena V. Preobrazhenskaya, Alexandr A. Romanko, Alexandr S. Martianov, Alexandr O. Ivantsov, Svetlana N. Aleksakhina, Alexandr V. Togo, Evgeny N. Imyanitov
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101121- (2021)
Background: Lorlatinib is a novel potent ALK inhibitor, with only a few studies reporting the results of its clinical use. Methods: This study describes the outcomes of lorlatinib treatment for 35 non-small cell lung cancer patients with ALK rearrang
Externí odkaz:
https://doaj.org/article/7a54773d24a54c3d9f4951da25379307
Autor:
Natalia V. Mitiushkina, Grigory A. Yanus, Ekatherina Sh. Kuligina, Tatiana A. Laidus, Alexandr A. Romanko, Maksim M. Kholmatov, Alexandr O. Ivantsov, Svetlana N. Aleksakhina, Evgeny N. Imyanitov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4586 (2022)
DNA from formalin-fixed paraffin-embedded (FFPE) tissues, which are frequently utilized in cancer research, is significantly affected by chemical degradation. It was suggested that approaches that are based on duplex sequencing can significantly impr
Externí odkaz:
https://doaj.org/article/4a0c1b7ad30142a6836a79f6cd5a3cff
Autor:
Anna P. Sokolenko, Luisa V. Sultanova, Ilya A. Stepanov, Alexandr A. Romanko, Aigul R. Venina, Tatiana N. Sokolova, Hedi S. Musayeva, Marina Ya. Tovgereeva, Mareta Kh. Magomedova, Khusein U. Akhmatkhanov, Elisa I. Vagapova, Elkhan A. Suleymanov, Elena V. Vasilyeva, Elvina Kh. Bakaeva, Ilya V. Bizin, Svetlana N. Aleksakhina, Evgeny N. Imyanitov
Publikováno v:
Cancer Medicine. 12:3167-3171
Coding sequences of BRCA1, BRCA2, ATM, TP53, and PALB2 genes were analyzed in 68 consecutive Chechen patients with high-grade serous ovarian cancer (HGSOC). Pathogenic BRCA1/2 variants were identified in 15 (22%) out of 68 HGSOC cases. Nine out of te
Autor:
Khristina B Kotiv, Evgeny N. Imyanitov, Anna P. Sokolenko, Alexandr O. Ivantsov, Alexandr A. Romanko, Tatiana I Ermachenkova, Elena V. Preobrazhenskaya, Tatiana V. Gorodnova, Robert V Broyde, Tatiana N. Sokolova, Ilya V. Bizin, Ekaterina Sh Kuligina
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:439-450
Patients with advanced high-grade serous ovarian cancer (HGSOC) are usually treated with paclitaxel and carboplatin; however, predictive markers for this drug combination are unknown. Tumor samples from 71 consecutive HGSOC patients, who received neo
Autor:
Maxim M. Kholmatov, Tatiana A. Laidus, Grigoriy Yanus, Kirill A. Zagorodnev, T. V. Sokolova, O. Vlasova, Alexandr A. Romanko, Vladislav Tyurin, Ekatherina Sh. Kuligina, Roman Meerovich, Aleksandr Martyanov, Maria O. Anisimova
Publikováno v:
Problems in oncology. 66:391-397
«Liquid biopsy» is gradually becoming a mandatory procedure in cancer diagnostics. The aim of this procedure is to detect and monitor tumor-specific markers in various body fluids (blood, urine, pleural fluid, etc.). Significant efforts have been m
Autor:
Ilya V. Bizin, Alexandr A. Bessonov, Mikhail A Maydin, Aldon J. Whitehead, Olga A Volynshchikova, Albina A Avanesyan, Elena I Anisimova, Valeria I. Ni, Alexandr M Scherbakov, Alexandr A. Romanko, Evgeny N. Imyanitov, Oleg B Tkachenko, Grigory A. Raskin, Alexandr O. Ivantsov, Maxim A Kleshchev, Tatiana V. Gorodnova, Ksenia Shelekhova, Robert V Broyde, Anna P. Sokolenko
Publikováno v:
Pathobiology. 87:367-374
Introduction: There is some evidence suggesting a link between BRCA1/2 germline mutations and increased risk of gastric cancer. Methods: Endoscopic screening for stomach malignancies was performed in 120 BRCA1 mutation carriers in order to evaluate t
Autor:
Evgeny N. Suspitsin, Peter Schürmann, Ilya V. Bizin, Maria O. Anisimova, Darya Prokofyeva, Aigul R. Venina, Elza Khusnutdinova, Tatiana N. Sokolova, Natalia Bogdanova, Ashok K. Varma, Evgeny N. Imyanitov, Maria A. Mantseva, Ekaterina Sh Kuligina, Andrey V. Koloskov, Syed K. Hasan, Ana Marija Milanović, Svetlana N. Aleksakhina, Anna P. Sokolenko, Marina Bermisheva, Daria D. Krylova, Kirill A. Zagorodnev, Thilo Dörk, Valeria I. Ni, Alexandr A. Romanko, Elena I Anisimova
Publikováno v:
Breast Cancer Research and Treatment. 179:731-742
Germline variants in known breast cancer (BC) predisposing genes explain less than half of hereditary BC cases. This study aimed to identify missing genetic determinants of BC. Whole exome sequencing (WES) of lymphocyte DNA was performed for 49 Russi