Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexander Zolotoy"'
Autor:
Eric S. Hayes, Gregory B Beatch, Alexander Zolotoy, Michael J A Walker, Bertrand Plouvier, Richard A. Wall
Publikováno v:
Current Medicinal Chemistry-Cardiovascular & Hematological Agents. 1:225-241
The data on the activities of all previously described HERG blockers and of the most widely cited I(Kr) blockers were analyzed with respect to the effect of potential charged center(s) and its shielding by surrounding structural elements. The followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7328df53527791ebcd7988291b2566
https://doi.org/10.2174/1568016033477432
https://doi.org/10.2174/1568016033477432
Autor:
Gregory N. Beatch, Alexander Zolotoy, Bertrand Plouvier, Terrance D. Barrett, Richard A. Wall, Michael J A Walker, Grace Jung
Publikováno v:
Drug Development Research. 55:45-52
Ventricular antiarrhythmic drugs in current clinical use leave much to be desired in terms of safety and efficacy. With the exception of beta-adrenoreceptor blockers, none of the available antiarrhythmic drugs have significantly improved survival aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b37815eca1ed7dc0bddaca3e3cdf4ac8
https://doi.org/10.1002/ddr.10038
https://doi.org/10.1002/ddr.10038
Autor:
Michael J A Walker, Alexander Zolotoy, Terrance D. Barrett, Eric S Hayes, Shlomo Abraham, Sandro L. Yong
Publikováno v:
European Journal of Pharmacology. 398:365-374
Eight novel and three reference antiarrhythmics were investigated in anaesthetised rats for antiarrhythmic actions, as well as for effects on the electrocardiogram (ECG) under normal and “simulated ischaemic” conditions. In rats subjected to coro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3354e9a063fdc8aae3cfbe8136b5f64a
https://doi.org/10.1016/s0014-2999(00)00295-8
https://doi.org/10.1016/s0014-2999(00)00295-8
Autor:
Richard A. Wall, David Fedida, Allen I. Bain, Terrance D. Barrett, Eric S. Hayes, Alexander Zolotoy, Bertrand Plouvier, Michael K. Pugsley, Mariah L. Walker, Michael J A Walker, Gregory N. Beatch, Sandro L. Yong
Publikováno v:
Drug Development Research. 42:198-210
RSD1000 is one example of a series of compounds synthesized by Nortran Pharmaceuticals, Inc., to provide selective protection against arrhythmias due to myocardial ischaemia and so providing better therapeutic indices than existing drugs. RSD1019 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca8aa95b591d29376f147c44dbfd226
https://doi.org/10.1002/(sici)1098-2299(199711/12)42:3/4<198::aid-ddr11>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199711/12)42:3/4<198::aid-ddr11>3.0.co
Autor:
Bertrand Plouvier, Gregory N. Beatch, Grace L. Jung, Alexander Zolotoy, Tao Sheng, Lilian Clohs, Terrance D. Barrett, David Fedida, Wei Q. Wang, Jeff J. Zhu, Yuzhong Liu, Shlomo Abraham, Leah Lynn, Ying Dong, Richard A. Wall, Michael J. A. Walker
Publikováno v:
Journal of Medicinal Chemistry; Jun2007, Vol. 50 Issue 12, p2818-2841, 24p