Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Alexander Zien"'
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e42947 (2012)
We provide a novel interpretation of the dual of support vector machines (SVMs) in terms of scatter with respect to class prototypes and their mean. As a key contribution, we extend this framework to multiple classes, providing a new joint Scatter SV
Externí odkaz:
https://doaj.org/article/b209e9da2a884ef38b8207f4798cff9b
A comprehensive review of an area of machine learning that deals with the use of unlabeled data in classification problems: state-of-the-art algorithms, a taxonomy of the field, applications, benchmark experiments, and directions for future research.
Autor:
Alexander Zientek, Michael Schagerl, Matthias Nagy, Wolfgang Wanek, Petra Heinz, Sameh S. Ali, Michael Lintner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Foraminifera are single-celled protists which are important mediators of the marine carbon cycle. In our study, we explored the potential impact of polystyrene (PS) microplastic particles on two symbiont-bearing large benthic foraminifera sp
Externí odkaz:
https://doaj.org/article/3bacbe7582c24c2dabb39588e311e828
Autor:
Christian Hachenberg, Marcel K.-P. Kusch, Alexander Zien, Walter E. Haefeli, Hanna M. Seidling
Publikováno v:
International journal of medical informatics. 133
Background The drug information most commonly requested by patients is to learn more about potential adverse drug reactions (ADRs) of their drugs. Such information should be customizable to individual information needs. While approaches to automatica
Autor:
David B. Jackson, Martin Stein, Sasha Badbanchi, Theodoros G. Soldatos, Alexander Picker, Francesca Diella, Alexander Zien, Markus Hartenfeller, Sonia Vivas
Publikováno v:
Cancer Research. 75:A1-33
Introduction: To accelerate the translation of genome information in important biological and clinical insights requires systematic integration and analysis of functional genomic and proteomic information. In this way molecular landscapes of cancer p
Autor:
Shelly Gunn, Martin Stein, Anja Doerks, Yunfei Wang, Markus Hartenfeller, Alexander Zien, Sasha Badbanchi, Stephan Brock, Francesca Diella, Steve Jones, David A. Jackson, Lina Asmar
Publikováno v:
Cancer Research. 75:P3-06
Background Among 493 patients with early stage, lower risk (70% node negative), HER2 positive breast cancer, the 2-year DFS was 97% with adjuvant docetaxel and cyclophosphamide plus 1 year of trastuzumab (TCH) in a phase 2 study (Jones et al, Lancet
Autor:
Lixia Diao, Chang Gong Liu, David A. Jackson, Liana Adam, Alexander Zien, Colin P.N. Dinney, Wang Jing, Jitao D. Zhang, Matthew F. Wszolek
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 31:1701-1708
Bladder cancer (BC) is a burdensome disease with significant morbidity, mortality, and cost. The development of novel plasma-based biomarkers for BC diagnosis and surveillance could significantly improve clinical outcomes and decrease health expendit
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 94
Systems pharmacology is used to mechanistically analyze drug-adverse drug reaction (ADRs) pairs and is a promising solution to the complex problem of understanding mechanisms of toxicity. In this research, we have explored the feasibility of retrospe
Publikováno v:
Clinical Orthopaedics and Related Research
The cDNA array technology is a powerful tool to analyze a high number of genes in parallel. We investigated whether large-scale gene expression analysis allows clustering and identification of cellular phenotypes of chondrocytes in different in vivo
Publikováno v:
Cancer Letters
Gene expression profiling of three chondrosarcoma derived cell lines (AD, SM, 105 KC) showed an increased proliferative activity and a reduced expression of chondrocytic-typical matrix products compared to primary chondrocytes. The incapability to ma