Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Alexander Zharkovsky"'
Autor:
Ling Yan, Yanli Li, Fengmei Fan, Mengzhuang Gou, Fangling Xuan, Wei Feng, Keerthana Chithanathan, Wei Li, Junchao Huang, Hongna Li, Wenjin Chen, Baopeng Tian, Zhiren Wang, Shuping Tan, Alexander Zharkovsky, L. Elliot Hong, Yunlong Tan, Li Tian
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Microglia are known to regulate stress and anxiety in both humans and animal models. Psychosocial stress is the most common risk factor for the development of schizophrenia. However, how microglia/brain macrophages contribute to s
Externí odkaz:
https://doaj.org/article/3688731ab7f54d3e93ad89bc88e2f32a
Autor:
Ling Yan, Fang-Ling Xuan, Song Chen, Mengzhuang Gou, Wenjin Chen, Yanli Li, Zhiren Wang, Leilei Wang, Ting Xie, Fengmei Fan, Alexander Zharkovsky, Yunlong Tan, Li Tian
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
BackgroundMicroglia play an important role in the maintenance of brain and behavioral homeostasis. The protective effect of microglial replenishment was reported in neurological diseases, but whether microglial therapy would benefit psychiatric disor
Externí odkaz:
https://doaj.org/article/390ce4c531bb4161b3dfa451de77e719
Autor:
Fang-Ling Xuan, Ling Yan, Yanli Li, Fengmei Fan, Hu Deng, Mengzhuang Gou, Keerthana Chithanathan, Indrek Heinla, Liang Yuan, Kadri Seppa, Alexander Zharkovsky, Anti Kalda, L. Elliot Hong, Guo-Fu Hu, Yunlong Tan, Li Tian
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stress is a trigger for the development of psychiatric disorders. However, how stress trait differs in schizophrenia patients is still unclear. Stress also induces and exacerbates immune activation in psychiatric disorders. Plexins (Plxn) and its lig
Externí odkaz:
https://doaj.org/article/e80d7331dc744fa08484c69174c8f6e7
Autor:
Keerthana Chithanathan, Monika Jürgenson, Mithu Guha, Ling Yan, Tamara Žarkovskaja, Martin Pook, Nathaniel Magilnick, Mark P. Boldin, Ana Rebane, Li Tian, Alexander Zharkovsky
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The miR-146 family consists of two microRNAs (miRNAs), miR-146a and miR-146b (miR-146a/b), both of which are known to suppress immune responses in a variety of conditions. Here, we studied how constitutive deficiency of miR-146b (Mir146b-/-) affects
Externí odkaz:
https://doaj.org/article/28cdd8f7d6cb4b09bc5d34cb564b556a
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The coronavirus disease 2019 (COVID-19) pandemic has generated a lot of stress and anxiety among not only infected patients but also the general population across the globe, which disturbs cerebral immune homeostasis and potentially exacerbates the S
Externí odkaz:
https://doaj.org/article/e284ee987e3d4837b65950a904607958
Autor:
Keerthana Chithanathan, Kelli Somelar, Monika Jürgenson, Tamara Žarkovskaja, Kapilraj Periyasamy, Ling Yan, Nathaniel Magilnick, Mark P. Boldin, Ana Rebane, Li Tian, Alexander Zharkovsky
Publikováno v:
Cells, Vol 11, Iss 13, p 2002 (2022)
The miR-146 family consists of two microRNAs (miRNAs), miR-146a and miR-146b, which are both known to suppress a variety of immune responses. Here in this study, we show that miR-146b is abundantly expressed in neuronal cells, while miR-146a is mainl
Externí odkaz:
https://doaj.org/article/f0b902e15dbd449e92e550f49f74d86f
Publikováno v:
International Journal of Ophthalmology, Vol 11, Iss 10, Pp 1608-1615 (2018)
AIM: To investigate the impact of polysialylated neural cell adhesion molecule (PSA-NCAM) on the survival of retinal ganglion cells (RGCs) in the experimentally induced diabetes in mice. METHODS: Diabetes was induced in 2.5 months old Swiss Webster
Externí odkaz:
https://doaj.org/article/064dd284c316477691d506e95d346785
Autor:
Maj N. Enevoldsen, Artur Kochoyan, Monika Jurgenson, Külli Jaako, Oksana Dmytriyeva, Peter S. Walmod, Jesper D. Nielsen, Janne Nielsen, Shizhong Li, Irina Korshunova, Boris Klementiev, Tatiana Novikova, Alexander Zharkovsky, Vladimir Berezin, Elisabeth Bock
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 3, Pp 533-545 (2012)
The fibroblast growth factor receptor (FGFR) plays a vital role in the development of the nervous system regulating a multitude of cellular processes. One of the interaction partners of the FGFR is the neural cell adhesion molecule (NCAM), which is k
Externí odkaz:
https://doaj.org/article/9fcbe29b8a84470280cc234b1ecce148
Autor:
Li Tian, Ling Yan, Yanli Li, Fengmei Fan, Fang-Ling Xuan, Wei Feng, Keerthana Chithanathan, Wei Li, Junchao Huang, Hongna Li, Mengzhuang Gou, Wenjin Chen, Baopeng Tian, Zhiren Wan, Shuping Tan, Alexander Zharkovsky, Elliot Hong, Yunlong Tan
Whether and how microglia contribute to stress and anxiety in schizophrenia are not well established. We hypothesized that microglial colony stimulating factor 1 receptor (CSF1R) regulates stress susceptibility in schizophrenia via the hippocampus an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4645c6ee4c7939c899668255951209f0
https://doi.org/10.21203/rs.3.rs-1777009/v1
https://doi.org/10.21203/rs.3.rs-1777009/v1
Autor:
Daniel Granato, Marina Fidelis, Marjo Haapakoski, Amanda dos Santos Lima, Janeli Viil, Jarkko Hellström, Reelika Rätsep, Hedi Kaldmäe, Uko Bleive, Luciana Azevedo, Varpu Marjomäki, Alexander Zharkovsky, Nora Pap
The effects of commercial enzymes (pectinases, cellulases, beta-1-3-glucanases, and pectin lyases) on the recovery of anthocyanins and polyphenols from blackcurrant press cake were studied considering two solid:solvent ratios (1:10 and 1:4 w/v). β-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc5bb3211194dd4a28a129016ad5012
https://figshare.com/articles/journal_contribution/Enzyme-assisted_extraction_of_anthocyanins_and_other_phenolic_compounds_from_blackcurrant_Ribes_nigrum_L_press_cake_From_processing_to_bioactivities/22227454
https://figshare.com/articles/journal_contribution/Enzyme-assisted_extraction_of_anthocyanins_and_other_phenolic_compounds_from_blackcurrant_Ribes_nigrum_L_press_cake_From_processing_to_bioactivities/22227454