Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Alexander Yu. Nikitin"'
Autor:
Andrea Flesken-Nikitin, Coulter Q. Ralston, Dah-Jiun Fu, Andrea J. De Micheli, Daryl J. Phuong, Blaine A. Harlan, Christopher S. Ashe, Amanda P. Armstrong, David W. McKellar, Sangeeta Ghuwalewala, Lora H. Ellenson, John C. Schimenti, Benjamin D. Cosgrove, Alexander Yu. Nikitin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The distal region of the uterine (Fallopian) tube is commonly associated with high-grade serous carcinoma (HGSC), the predominant and most aggressive form of ovarian or extra-uterine cancer. Specific cell states and lineage dynamics of the a
Externí odkaz:
https://doaj.org/article/90512a4f897946e0b160380da2b3bd0c
Autor:
Dah-Jiun Fu, Andrea J. De Micheli, Blaine A. Harlan, Mallikarjun Bidarimath, Lora H. Ellenson, Benjamin D. Cosgrove, Andrea Flesken-Nikitin, Alexander Yu. Nikitin
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/5a74e5f4b99348fba6cff2da4c9d74bf
Autor:
Lucy Penfold, Angela Woods, Alice E. Pollard, Julia Arizanova, Eneko Pascual-Navarro, Phillip J. Muckett, Marian H. Dore, Alex Montoya, Chad Whilding, Louise Fets, Joao Mokochinski, Theodora A. Constantin, Anabel Varela-Carver, Damien A. Leach, Charlotte L. Bevan, Alexander Yu. Nikitin, Zoe Hall, David Carling
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112396- (2023)
Summary: Emerging evidence indicates that metabolic dysregulation drives prostate cancer (PCa) progression and metastasis. AMP-activated protein kinase (AMPK) is a master regulator of metabolism, although its role in PCa remains unclear. Here, we sho
Externí odkaz:
https://doaj.org/article/11a6b824917b48fc8d5c5b5a9e0faa99
Autor:
Dah-Jiun Fu, Lianghai Wang, Fouad K. Chouairi, Ian M. Rose, Danysh A. Abetov, Andrew D. Miller, Robert J. Yamulla, John C. Schimenti, Andrea Flesken-Nikitin, Alexander Yu. Nikitin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Cancers arising from the gastric squamous-columnar junction have high incidence and are characterized by a poor prognosis. Here, the authors use genetic mouse models to show that loss of p53 and Rb1 expression results in preferential tumour developme
Externí odkaz:
https://doaj.org/article/cc9b087fae6a467297a9cdf23f9d6ec2
Autor:
Dah-Jiun Fu, Andrea J. De Micheli, Mallikarjun Bidarimath, Lora H. Ellenson, Benjamin D. Cosgrove, Andrea Flesken-Nikitin, Alexander Yu. Nikitin
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 10 (2020)
Humans and mice have cyclical regeneration of the endometrial epithelium. It is expected that such regeneration is ensured by tissue stem cells, but their location and hierarchy remain debatable. A number of recent studies have suggested the presence
Externí odkaz:
https://doaj.org/article/371ff2ddb7c04827ae1de1664a9a50c3
Autor:
Chieh-Yang Cheng, Chang-Il Hwang, David C. Corney, Andrea Flesken-Nikitin, Longchang Jiang, Gülfem Meryem Öner, Robert J. Munroe, John C. Schimenti, Heiko Hermeking, Alexander Yu. Nikitin
Publikováno v:
Cell Reports, Vol 6, Iss 6, Pp 1000-1007 (2014)
The miR-34 family was originally found to be a direct target of p53 and is a group of putative tumor suppressors. Surprisingly, mice lacking all mir-34 genes show no increase in cancer formation by 18 months of age, hence placing the physiological re
Externí odkaz:
https://doaj.org/article/eb540098fec04f6a8ededd0404e03aaa
Publikováno v:
EBioMedicine, Vol 2, Iss 10, Pp 1268-1269 (2015)
Externí odkaz:
https://doaj.org/article/d4139d85ce7f475598269eefe74ce717
Autor:
Chieh-Yang Cheng, Chang-Il Hwang, David C. Corney, Andrea Flesken-Nikitin, Longchang Jiang, Gülfem Meryem Öner, Robert J. Munroe, John C. Schimenti, Heiko Hermeking, Alexander Yu. Nikitin
Publikováno v:
Cell Reports, Vol 12, Iss 12, p 2181 (2015)
Externí odkaz:
https://doaj.org/article/b2c16592bd084985a572ea2becd8d759
Autor:
David MacPherson, Nicholas Ingolia, Alexander Yu. Nikitin, Susan Parazzoli, Karina Conkrite, Michael Rongione, Arnaud Augert, Min Cui
XLSX file - 38KB, Supplemental Table 1. Primer sequences used for Real Time PCR Supplemental Table 2. Coverage of mouse exome samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1319093ef0c07c1a501aaa12427be207
https://doi.org/10.1158/1541-7786.22511250
https://doi.org/10.1158/1541-7786.22511250
Autor:
David MacPherson, Nicholas Ingolia, Alexander Yu. Nikitin, Susan Parazzoli, Karina Conkrite, Michael Rongione, Arnaud Augert, Min Cui
PDF file - 1172KB, S1. Neuroendocrine lung tumors in Rb/p53 AdCre model. S2. Neuroendocrine lung tumors in Rb/p53/Ptenlox/+AdCre model. S3. Analyses of Rb, p53 and Pten recombination in lung tumors. S4. Comparison of Rb/p53/Ptenlox/+ vs. Rb/p53/Ptenl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743e5daae561e65e2ef776eab2ad15d9
https://doi.org/10.1158/1541-7786.22511253.v1
https://doi.org/10.1158/1541-7786.22511253.v1