Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexander Y Jiu"'
Publikováno v:
Angewandte Chemie (International ed. in English), vol 60, iss 36
Angew Chem Int Ed Engl
Angew Chem Int Ed Engl
We report the first enantioselective addition of pyrazoles to 1,3-dienes. Secondary and tertiary allylic pyrazoles can be generated with excellent regioselectivity. Mechanistic studies support a pathway distinct from previous hydroaminations: a Pd(0)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4d6da49e068afbad34ddd0b2742a14
https://escholarship.org/uc/item/8g66d075
https://escholarship.org/uc/item/8g66d075
Autor:
Nick A. Paras, Daniel G Droege, Takao Ohyama, Jay Conrad, Shimpei Hirano, Roy J. Vaz, Stanley B. Prusiner, Sasaki Koji, Steven H. Olson, Alexander Y Jiu, John W West, Masahiro Inoue, Makoto Hirasawa, Benjamin C Tang, Jean-Marc M Grandjean, Manuel Elepano, Ryo Murakami, Joanne Lee, Masakazu Hirouchi, Atsushi Aoyagi
Publikováno v:
ACS medicinal chemistry letters, vol 11, iss 2
ACS Med Chem Lett
ACS Med Chem Lett
[Image: see text] Tau prions feature in the brains of patients suffering from Alzheimer’s disease and other tauopathies. For the development of therapeutics that target the replication of tau prions, a high-content, fluorescence-based cell assay wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f91271b5afcc886791b89cc2cad0e9
https://escholarship.org/uc/item/4cz02519
https://escholarship.org/uc/item/4cz02519
Autor:
Connor J O'Brien, Jay Conrad, Alexander Y Jiu, Shivaani S Gandhi, Daniel G Droege, Nick A. Paras, Steven H. Olson
Publikováno v:
The Journal of organic chemistry, vol 83, iss 16
The direct cyanomethylation of indoles at the 2- or 3-position was achieved via photoredox catalysis. The versatile nitrile synthon is introduced as a radical generated from bromoacetonitrile, a photocatalyst, and blue LEDs as a light source. The mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510ca1f2ad6d7a2e5a50ec5178bf400d
https://escholarship.org/uc/item/33w8z2g8
https://escholarship.org/uc/item/33w8z2g8