Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexander W. Sun"'
Autor:
Nikhita Kathuria-Prakash, Lauren Antrim, Nicholas Hornstein, Alexander W. Sun, Irene M. Kang, Nikita V. Baclig, Trevor E. Angell, Melissa G. Lechner, Noah Wald-Dickler, Gino K. In
Publikováno v:
Clinical breast cancer, vol 22, iss 4
Clinical Breast Cancer
Clinical Breast Cancer
BackgroundThe SARS-CoV-2 virus has infected and killed millions of people worldwide. Breast cancer is the most prevalent cancer in women and few studies have investigated the outcomes of patients with a history of breast cancer and COVID-19. We repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf4bfc875dcf58cc497f6539eb86ff0
https://escholarship.org/uc/item/9553q1zr
https://escholarship.org/uc/item/9553q1zr
Autor:
Dimitrios Stefanoudakis, Nikhita Kathuria-Prakash, Alexander W. Sun, Melissa Abel, Claire E. Drolen, Camille Ashbaugh, Shiliang Zhang, Gavin Hui, Yeganeh A. Tabatabaei, Yuliya Zektser, Lidia P. Lopez, Allan Pantuck, Alexandra Drakaki
Publikováno v:
Cancers, vol 15, iss 6
Immuno-oncology (IO) and targeted therapies, such as small molecule inhibitors, have changed the landscape of cancer treatment and prognosis; however, durable responses have been difficult to achieve due to tumor heterogeneity, development of drug re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6b1b7625dd1b75bd649550e65db0d6
https://doi.org/10.3390/cancers15061813
https://doi.org/10.3390/cancers15061813
Autor:
Heta S. Desai, Tianyang Yan, Fengchao Yu, Alexander W. Sun, Miranda Villanueva, Alexey I. Nesvizhskii, Keriann M. Backus
Publikováno v:
Molecular & cellular proteomics : MCP, vol 21, iss 4
Proteinaceous cysteine residues act as privileged sensors of oxidative stress. As reactive oxygen and nitrogen species have been implicated in numerous pathophysiological processes, deciphering which cysteines are sensitive to oxidative modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5787743b31eb8b92937195c6bbf1e67c
https://pubmed.ncbi.nlm.nih.gov/35219905
https://pubmed.ncbi.nlm.nih.gov/35219905
A variety of enantioenriched gem-disubstituted 4-imidazolidinones were prepared in up to >99% yield and 95% ee by the Pd-catalyzed decarboxylative asymmetric allylic alkylation of imidazolidinone-derived β-amidoesters. In the process of preparing th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016f9f6a3fe9b1bb8a7ceb46ca6fc970
https://resolver.caltech.edu/CaltechAUTHORS:20210823-170520379
https://resolver.caltech.edu/CaltechAUTHORS:20210823-170520379
Publikováno v:
Org Lett
A variety of enantioenriched gem-disubstituted 4-imidazolidinones were prepared in up to >99% yield and 95% ee by the Pd-catalyzed decarboxylative asymmetric allylic alkylation of imidazolidinone-derived β-amidoesters. In the process of preparing th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d5321d3f6e4e93520a8fc9798a3cd36
https://pubmed.ncbi.nlm.nih.gov/34346221
https://pubmed.ncbi.nlm.nih.gov/34346221
Publikováno v:
Trends in Chemistry. 1:630-643
As the field of synthetic chemistry seeks to tackle new frontiers, total synthesis is primed to address significant medical challenges such as the rise of antibiotic resistance and cancer. One emerging frontier focuses on increasingly concerted effor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156d42d203ebfb7b35b35ab4b9e0783e
https://doi.org/10.1016/j.trechm.2019.05.008
https://doi.org/10.1016/j.trechm.2019.05.008
Autor:
Alexander W. Sun, Brian M. Stoltz
Publikováno v:
Organic Syntheses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34334853720b6a20b92eadfeffeb515f
https://doi.org/10.1002/0471264229.os095.29
https://doi.org/10.1002/0471264229.os095.29
Publikováno v:
Chemical Science. 10:788-792
An enantioselective synthesis of diverse N4-Boc-protected α,α-disubstituted piperazin-2-ones using the palladium-catalyzed decarboxylative allylic alkylation reaction has been achieved. Using a chiral Pd-catalyst derived from an electron deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a3394b106721889f32d7c8ac914afc
https://doi.org/10.1039/c8sc03967d
https://doi.org/10.1039/c8sc03967d
Publikováno v:
Org Lett
We report the palladium-catalyzed asymmetric allylic alkylation of 1,4-diazepan-5-ones. This reaction proceeds smoothly to give gem-disubstituted diazepanone heterocycles bearing various functional groups in up to >99% yield and up to 95% ee. An elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c18b4ef21b912a5848b553fbfd41917
https://europepmc.org/articles/PMC8579948/
https://europepmc.org/articles/PMC8579948/
Autor:
O'boyle Brendan M, Peter Jorth, Philip L. Bulterys, Michael D. Bartberger, Alexander W. Sun, Scott C. Virgil, Brian M. Stoltz, Jeff F. Miller
Publikováno v:
Bioorg Med Chem Lett
gem-Disubstituted N-heterocycles are rarely found in drugs, despite their potential to improve the drug-like properties of small molecule pharmaceuticals. Linezolid, a morpholine heterocycle-containing oxazolidinone antibiotic, exhibits significant s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d9bb33f75380797dfa1674038bfb43
https://resolver.caltech.edu/CaltechAUTHORS:20190718-083115245
https://resolver.caltech.edu/CaltechAUTHORS:20190718-083115245