Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alexander W. Lange"'
Autor:
David H Tompkins, Valérie Besnard, Alexander W Lange, Susan E Wert, Angela R Keiser, April N Smith, Richard Lang, Jeffrey A Whitsett
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8248 (2009)
The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis. In the
Externí odkaz:
https://doaj.org/article/58b31ed016d04989aa5e0ec5a0d10e2c
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5711 (2009)
The Sry-related high mobility group box transcription factor Sox17 is required for diverse developmental processes including endoderm formation, vascular development, and fetal hematopoietic stem cell maintenance. Expression of Sox17 in mature respir
Externí odkaz:
https://doaj.org/article/a4d6833bc7d3455a9b64569a1f1f3a0b
Autor:
Barry R. Stripp, Alexander W. Lange, Anne-Karina T. Perl, Anusha Sridharan, Jeffrey A. Whitsett, Yan Xu
Publikováno v:
Journal of molecular cell biology, vol 7, iss 1
The Hippo/Yap pathway is a well-conserved signaling cascade that regulates cell proliferation and differentiation to control organ size and stem/progenitor cell behavior. Following airway injury, Yap was dynamically regulated in regenerating airway e
Autor:
Andrew M. Lowy, James M. Wells, Injune Kim, Jeffrey A. Whitsett, Suh Chin J. Lin, Klaus H. Kaestner, Jason R. Spence, Alexander W. Lange
Publikováno v:
Developmental Cell. 17:62-74
SummaryThe ventral pancreas, biliary system, and liver arise from the posterior ventral foregut, but the cell-intrinsic pathway by which these organ lineages are separated is not known. Here we show that the extrahepatobiliary system shares a common
Publikováno v:
Developmental Biology. 294(2):292-302
The mature heart valves are dynamic structures composed of highly organized cell lineages and extracellular matrices. The discrete architecture of connective tissue within valve leaflets and supporting structures allows the valve to withstand life-lo
Publikováno v:
Developmental Biology. 292:407-417
NFATc1 is necessary for remodeling endocardial cushions into mature heart valve leaflets and is also an essential effector of receptor activator of NFκB ligand (RANKL) signaling required for transcriptional activation of bone matrix remodeling enzym
Publikováno v:
Developmental Biology. 266(2):346-360
The Down syndrome critical region 1 (DSCR1) gene is present in the region of human chromosome 21 and the syntenic region of mouse chromosome 16, trisomy of which is associated with congenital heart defects observed in Down syndrome. DSCR1 encodes a r
Publikováno v:
C16. BEST OF PEDIATRICS.
Autor:
Caitlin M. Braitsch, Katherine E. Yutzey, Jeanne James, Michelle D. Combs, Alexander W. Lange
Epicardium-derived cells (EPDCs) contribute to formation of coronary vessels and fibrous matrix of the mature heart. Nuclear factor of activated T-cells cytoplasmic 1 (NFATC1) is expressed in cells of the proepicardium (PE), epicardium and EPDCs in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64cf7386481429825eade509328ee84
https://europepmc.org/articles/PMC3074451/
https://europepmc.org/articles/PMC3074451/
Autor:
Jeffrey A. Whitsett, David H. Tompkins, Richard A. Lang, Angela R. Keiser, Alexander W. Lange, Susan E. Wert, April N. Smith, Valérie Besnard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 12, p e8248 (2009)
PLoS ONE, Vol 4, Iss 12, p e8248 (2009)
The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis. In the