Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Alexander W Kay"'
Autor:
Tara E Ness, Ashish E Streatfield, Tandzile Simelane, Abiy Korsa, Sandile Dlamini, Danielle Guffey, Bhekumusa Lukhele, Alexander W Kay
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244247 (2021)
In a human immunodeficiency virus (HIV) clinic for children and their families in Eswatini, we sought to understand the use of antibiotics and identify specific areas for improvement. We performed a retrospective patient chart review as part of a qua
Externí odkaz:
https://doaj.org/article/67d990485b2f4590b299e48d644923d7
Autor:
Alexander W Kay, Neil Thivalapill, Donald Skinner, Gloria Sisi Dube, Nomathemba Dlamini, Bulisile Mzileni, Patricia Fuentes, Pilar Ustero, Lisa V Adams, Anna M Mandalakas
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243713 (2020)
This study identified factors associated with adherence to a 6-month isoniazid preventive therapy (IPT) course among adolescents and children living with HIV. Forty adolescents living with HIV and 48 primary caregivers of children living with HIV com
Externí odkaz:
https://doaj.org/article/cde6e3878b444fbf80c65ab7efb36007
Autor:
Piluca Alonzo Ustero, Alexander W Kay, Katherine Ngo, Rachel Golin, Bhekisisa Tsabedze, Bulisile Mzileni, Jessica Glickman, Mildred Wisile Xaba, Gcinile Mavimbela, Anna Maria Mandalakas
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178873 (2017)
BACKGROUND:Investigation of household contacts exposed to infectious tuberculosis (TB) is widely recommended by international guidelines to identify secondary cases of TB and limit spread. There is little data to guide the use of contact investigatio
Externí odkaz:
https://doaj.org/article/a0b79d76068d486f965111ac11698837
Autor:
Alexander W Kay, Catherine A Blish
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Pregnant women are at high risk from influenza due to disproportionate morbidity, mortality, and adverse pregnancy outcomes following infection. As such, they are classified as a high priority group for vaccination. However, changes in the maternal i
Externí odkaz:
https://doaj.org/article/2c3f4b18443f49e1a494002f4c8cb4b1
Autor:
Alexander W. Kay, Helena Rabie, Elizabeth Maleche-Obimbo, Moorine Penninah Sekadde, Mark F. Cotton, Anna M. Mandalakas
Publikováno v:
Pathogens, Vol 11, Iss 1, p 33 (2021)
Children and adolescents living with HIV continue to be impacted disproportionately by tuberculosis as compared to peers without HIV. HIV can impact TB screening and diagnosis by altering screening and diagnostic test performance and can complicate p
Externí odkaz:
https://doaj.org/article/02d8aa6d453e46cc877284a4affc0450
Autor:
Mathieu Le Gars, Christof Seiler, Alexander W. Kay, Nicholas L. Bayless, Elina Starosvetsky, Lindsay Moore, Shai S. Shen-Orr, Natali Aziz, Purvesh Khatri, Cornelia L. Dekker, Gary E. Swan, Mark M. Davis, Susan Holmes, Catherine A. Blish
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Pregnant women are particularly susceptible to complications of influenza A virus infection, which may result from pregnancy-induced changes in the function of immune cells, including natural killer (NK) cells. To better understand NK cell function d
Externí odkaz:
https://doaj.org/article/3ebfba4f605d4fb48eb479e2c9e2771d
Autor:
Alexander W Kay, Tara Ness, Sabine E Verkuijl, Kerri Viney, Annemieke Brands, Tiziana Masini, Lucia González Fernández, Michael Eisenhut, Anne K Detjen, Anna M Mandalakas, Karen R Steingart, Yemisi Takwoingi
Publikováno v:
The Cochrane Database of Systematic Reviews
Background Every year, at least one million children become ill with tuberculosis and around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization (WHO)‐recommended rapid molecular tests that simultaneously detect tuberc
Autor:
Angelina Kayabu, Alexander W. Kay, Moorine Penninah Sekadde, Andrew R. DiNardo, Sandile Dlamini, David Damba, Makhorong Matsoso, Mogo Matshaba, Richard S. Wanless, Rachel Golin, Lineo Thahane, Tara Devezin, Joseph Mhango, Saeed Ahmed, Bhekumusa Lukhele, Dilsher Dhillon, Katherine R Simon, Moses Chodota, Pauline Amuge, Jill Sanders, Gordon E. Schutze, Anna M. Mandalakas, Neway G Fida, Nodumo Chidah, Jason M. Bacha
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 12, Pp 2933-2943 (2020)
Emerging Infectious Diseases
Emerging Infectious Diseases
HIV-infected children and adolescents are at increased risk for tuberculosis (TB). Antiretroviral therapy (ART) reduces TB risk in HIV-infected adults, but its effectiveness in HIV-infected children and adolescents is unknown. We analyzed data from 7
Autor:
Zhen Huang, Sylvia M LaCourse, Alexander W Kay, Joshua Stern, Jaclyn N Escudero, Brady M Youngquist, Wenshu Zheng, Debrah Vambe, Muyalo Dlamini, Godwin Mtetwa, Lisa M Cranmer, Irene Njuguna, Dalton C Wamalwa, Elizabeth Maleche-Obimbo, Donald G Catanzaro, Christopher J Lyon, Grace John-Stewart, Andrew DiNardo, Anna M Mandalakas, Bo Ning, Tony Y Hu
Publikováno v:
The Lancet. Microbe. 3(7)
Tuberculosis remains a leading cause of global mortality, especially for adults and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum-based assays are needed to improve tuberculosis diagnosis and tuberculosis treatmen
Autor:
M. G. Dlamini, Alexander W. Kay, C. L. Jasumback, G. S. Dube, H. L. Kirchner, Andrew R. DiNardo, Anna M. Mandalakas, G. Maphalala, Qiniso Dlamini, J. Kahari
Publikováno v:
Public Health Action
TB disease diagnosis in children is difficult due to non-specific symptoms, paucibacillary disease and the need for invasive procedures to obtain diagnostic specimens. In many settings, these specimens are simply not collected and therefore stool, ea